BOC-LEU-GLY-OH

Product Name: BOC-LEU-GLY-OH
CAS No.: 32991-17-6
Chemical Name: BOC-LEU-GLY-OH
Synonyms: BOC-LEU-GLY-OH;Boc-L-Leu-Gly-OH;N-Boc-L-leucyl-glycine;Boc-Leu-Gly-OH≥ 99% (TLC);(Tert-Butoxy)Carbonyl Leu-Gly-OH;tert-(Butyloxycarbonyl)leucylglycine;(tert-Butoxycarbonyl)-L-leucylglycine;N-(tert-Butoxycarbonyl)-L-leucylglycine;N-[(1,1-Dimethylethoxy)carbonyl]-L-leucylglycine;Glycine, N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-
CBNumber: CB0189132
Molecular Formula: C13H24N2O5
Formula Weight: 288.34
MOL File: 32991-17-6.mol

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BOC-LEU-GLY-OH Property

Boiling point:: 499.6±30.0 °C(Predicted)
Density: 1.122±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
form: Solid
pka: 3.42±0.10(Predicted)
color: White to off-white
optical activity: Consistent with structure

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Safety

HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D473605
Product name: N-[N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl]-glycine
Packaging: 500mg
Price: $90
Updated: 2021/12/16

Usbiological

Product number: 264957
Product name: Boc-Leu-Gly-OH
Packaging: 500mg
Price: $375
Updated: 2021/12/16

Activate Scientific

Product number: AS35132
Product name: (S)-2-(2-((tert-Butoxycarbonyl)amino)-4-methylpentanamido)acetic acid
Purity: 97+% ee
Packaging: 1g
Price: $35
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB48201
Product name: Boc-Leu-Gly-OH
Packaging: 500mg
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: W5471
Product name: (S)-2-(2-((tert-Butoxycarbonyl)amino)-4-methylpentanamido)aceticacid
Packaging: 1g
Price: $89
Updated: 2021/12/16

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BOC-LEU-GLY-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

N-[N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl]-glycine is used to prepare aziridinedicarboxylic acid peptides as cysteine protease inhibitors. It is also used to prepare dipeptide monoester prodrugs of floxuridine with enhanced cancer cell growth inhibition.

Synthesis

27610-07-7

32991-17-6

General procedure for the synthesis of (S)-2-(2-((tert-butoxycarbonyl)amino)-4-methylpentanamido)acetic acid from (tert-butoxycarbonyl)-L-leucylglycine methyl ester: Compound 9a (2.6 g, 10 mmol) was dissolved in 50 mL of methanol, 1 M NaOH solution (30 mL) was added, and the reaction was stirred for 3 h at room temperature. Upon completion of the reaction, the solvent was removed by vacuum concentration and the pH of the residue was adjusted to 2-3 with 1 M HCl. Subsequently, the mixture was extracted three times with ethyl acetate (EtOAc). The organic phases were combined and dried over anhydrous sodium sulfate (Na2SO4). After filtration, ethyl acetate was evaporated under reduced pressure to give compound 10a as a white solid in 92.4% yield.

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 11, p. 3055 - 3064
[2] Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2009, vol. 64, # 2, p. 237 - 244
[3] Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 2, p. 887 - 895

BOC-LEU-GLY-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-LEU-GLY-OH Suppliers

China 73 India 2 United Kingdom 2 United States 9 Global 86

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Shanghai Balmxy Pharmaceutical Co., Ltd

Tel: 021-24206007 13764915196
Fax: 86-021-23027023
Email: sales@balmxy.com
Country: China
ProdList: 6874
Advantage: 55

NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4613
Advantage: 58

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7992
Advantage: 55

Shanghai GL Peptide Ltd.

Tel: +86-21-61263340; 17609490614 13764994101
Fax: 021-61263399
Email: fisherwang@glschina.com
Country: China
ProdList: 8258
Advantage: 55

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View Lastest Price from BOC-LEU-GLY-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-Leu-Gly-OH 32991-17-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-03-26

Henan Aochuang Chemical Co.,Ltd.

Product: BOC-LEU-GLY-OH 32991-17-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

Shaanxi Dideu Medichem Co. Ltd

Product: BOC-LEU-GLY-OH 32991-17-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-14

32991-17-6, BOC-LEU-GLY-OHRelated Search:

BOC-D-PHE-PRO-OH BOC-VAL-GLY-OH N-(tert-Butoxycarbonyl)-L-glutamine BOC-Glycine Boc-L-Glutamic acid 5-benzylester BOC-LEU-LEU-OH BOC-LEU-OSU BOC-DAP(FMOC)-OH N-Boc-N'-trityl-L-glutamine BOC-DAP(Z)-OH Boc-L-Glutamic acid 1-benzyl ester BOC-LEU-MET-OH BOC-LEU-LEU-OME BOC-LEU-GLY-OH BOC-LEU-LEU-OH BOC-LEU-PRO-OH (3S)-4-BOC-1-CARBOXYMETHYL-3-ISOBUTYL-PIPERAZIN-2-ONE BOC-LEU-MET-OME

BOC-LEU-GLY-OH

N-[(1,1-Dimethylethoxy)carbonyl]-L-leucylglycine

Boc-L-Leu-Gly-OH

N-(tert-Butoxycarbonyl)-L-leucylglycine

(S)-2-(2-((tert-Butoxycarbonyl)aMino)-4-MethylpentanaMido)acetic acid

tert-(Butyloxycarbonyl)leucylglycine

Boc-Leu-Gly-OH≥ 99% (TLC)

(Tert-Butoxy)Carbonyl Leu-Gly-OH

(tert-Butoxycarbonyl)-L-leucylglycine

2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-methylpentanamido]acetic acid

Glycine, N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-

2-[[(2S)-4-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoyl]amino]acetic acid

N-Boc-L-leucyl-glycine

32991-17-6