ChemicalBook > CAS DataBase List > L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Description- Product Name
- L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
- CAS No.
- 74163-81-8
- Chemical Name
- L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
- Synonyms
- Tic-OH;(S)-TIC;L-TIC HCL;L-1,2,3,4-Tetrahydro;Icatibant Impurity 14;Quinapril Bicyclic Acid;Quinapril EP Impurity A;(S)-1,2,3,4-Tetrahydro-3-isoquinoL;Quinapril Hydrochloride Impurity A;(3S)-1,2,3,4-Tetrahydroisoquinoline
- CBNumber
- CB0197924
- Molecular Formula
- C10H11NO2
- Formula Weight
- 177.2
- MOL File
- 74163-81-8.mol
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L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Property
- Melting point:
- >300 °C(lit.)
- alpha
- -157.4 º (24 ºC)
- Boiling point:
- 309.12°C (rough estimate)
- Density
- 1.1607 (rough estimate)
- refractive index
- -166 ° (C=1, 1mol/L NaOH)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- soluble in Hot Water, Basic Water
- pka
- 2.21±0.20(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- optical activity
- [α]20/D 168°, c = 1.8 in 1.4 M NaOH
- BRN
- 4842199
- InChIKey
- BWKMGYQJPOAASG-VIFPVBQESA-N
- CAS DataBase Reference
- 74163-81-8(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- HS Code
- 29334900
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 421626
- Product name
- (S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $25
- Updated
- 2024/03/01
TCI Chemical
- Product number
- T1515
- Product name
- (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $72
- Updated
- 2024/03/01
TCI Chemical
- Product number
- T1515
- Product name
- (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $208
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L14422
- Product name
- (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, 97%
- Packaging
- 1g
- Price
- $23.65
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L14422
- Product name
- (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, 97%
- Packaging
- 5g
- Price
- $65.65
- Updated
- 2024/03/01
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L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Chemical Properties,Usage,Production
Description
(S)-(-)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is a quinoline derivative, which is used as an intermediate in the synthesis of quinapril. Quinapril, a product developed by Pfizer, was approved by the US FDA in 1991 for the treatment of hypertension, congestive heart failure and angioedema.
Chemical Properties
white to light yellow crystal powde
Uses
(S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid (Quinapril EP Impurity A) is a Quinapril intermediate.
L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Suppliers
- Tel
- --
- Fax
- --
- fo@acros.com
- Country
- Belgium
- ProdList
- 3824
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@acros.com
- Country
- Belgium
- ProdList
- 6772
- Advantage
- 81
- Tel
- --
- Fax
- --
- eburon@innet.be
- Country
- Belgium
- ProdList
- 490
- Advantage
- 66
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View Lastest Price from L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid manufacturers
Henan Aochuang Chemical Co.,Ltd.
- Product
- L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid 74163-81-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-09
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid 74163-81-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid 74163-81-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
74163-81-8, L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acidRelated Search:
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