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Quinapril hydrochloride

Product Name
Quinapril hydrochloride
CAS No.
82586-55-8
Chemical Name
Quinapril hydrochloride
Synonyms
ACCUPRIL;QUINAPRIL HCL;Korec;Conan;CI-906;Acupril;ccupril;ACCUPRO;Acequin;Acuitel
CBNumber
CB8100984
Molecular Formula
C25H31ClN2O5
Formula Weight
474.98
MOL File
82586-55-8.mol
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Quinapril hydrochloride Property

Melting point:
120-130°C
alpha 
D23 +14.5° (c = 1.2 in ethanol) (Klutchko); D25 +15.4° (c = 2 in methanol) (Goel, Krolls)
storage temp. 
2-8°C
solubility 
H2O: >10mg/mL
form 
solid
color 
white
CAS DataBase Reference
82586-55-8(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
2
RTECS 
NW7176000
HS Code 
2933492250
Hazardous Substances Data
82586-55-8(Hazardous Substances Data)
Toxicity
Freely sol in aq solvents. LD50 in male, female mice, rats (mg/kg): 1739, 1840, 4280, 3541 orally; 504, 523, 158, 107 i.v. (Kaplan, 1989)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Q0632
Product name
Quinapril hydrochloride
Purity
≥98% (HPLC), solid
Packaging
250mg
Price
$654
Updated
2024/03/01
Sigma-Aldrich
Product number
BP1193
Product name
Quinapril hydrochloride
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$229
Updated
2024/03/01
Sigma-Aldrich
Product number
1593401
Product name
Quinapril hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
400mg
Price
$364.4
Updated
2024/03/01
Alfa Aesar
Product number
J61913
Product name
Quinapril hydrochloride, 98%
Packaging
1g
Price
$255.65
Updated
2024/03/01
Alfa Aesar
Product number
J61913
Product name
Quinapril hydrochloride, 98%
Packaging
5g
Price
$650.65
Updated
2024/03/01
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Quinapril hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

Antihypertensive;Dopamine receptor agonist

Uses

Quinapril is an angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.

Uses

Quinapril hydrochloride has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on renal tubular epithelial cell proliferation in human renal tubular epithelial cells. It has also been used as an ACE inhibitor to evaluate its effects on the expression of angiotensin II (AII) in patient-derived Atheroma samples.

Definition

ChEBI: Quinapril hydrochloride is a hydrochloride resulting from the reaction of equimolar amounts of quinapril and hydrogen chloride. A prodrug for quinaprilat hydrochloride (by hydrolysis of the ethyl ester to the corresponding carboxylic acid), it is used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure. It has a role as an antihypertensive agent and an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. It contains a quinapril(1+).

brand name

Accupril (Pfizer); Quinapril (Lupin); Quinapril (Ranbaxy) .

General Description

Quinapril hydrochloride,(S)-[(S)-N-[(S)21-carboxy3-phenylpropyl]alanyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid 1-ethyl ester hydrochloride(Acuretic), forms the diacid quinaprilate in thebody. It is more potent than captopril and equipotent to theactive form of enalapril.

Biochem/physiol Actions

Quinapril is a short-acting angiotensin converting enzyme (ACE) inhibitor.

Quinapril hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Quinapril hydrochloride Suppliers

Zhejiang Huahai Pharmaceutical Co., Ltd
Tel
057685016990 15014006640
Fax
86-21-53086382
Email
qiangl999@sina.com
Country
China
ProdList
111
Advantage
75
Wuhan Dingxintong Pharmaceutical Co. , Ltd.
Tel
027-027-52344656 15871722230
Fax
2796190295
Email
15871722230@163.com
Country
China
ProdList
4710
Advantage
58
Jiangxi ravel Biotechnology Co.,Ltd
Tel
185-0276-2003 18502762003;
Email
435918333@qq.com
Country
China
ProdList
2285
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8844
Advantage
52
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
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View Lastest Price from Quinapril hydrochloride manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Quinapril hydrochloride 82586-55-8
Price
US $99.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1 ton
Release date
2021-12-21
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Quinapril hydrochloride 82586-55-8
Price
US $19.00/KG
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20tons
Release date
2021-12-31
Zhuozhou Wenxi import and Export Co., Ltd
Product
Quinapril hydrochloride 82586-55-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

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