OPHIOBOLIN B
- Product Name
- OPHIOBOLIN B
- CAS No.
- 5601-74-1
- Chemical Name
- OPHIOBOLIN B
- Synonyms
- OPHIOBOLIN B;Cochliobolin B;Ophiobolin B (Cochliobolin B);Cochliobolin B, Zizanin B, Ophiobolsin A;3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al;Dicyclopenta[a,d]cyclooctene-4-carboxaldehyde, 7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1,7-dihydroxy-1,9a-dimethyl-3-oxo-, (1R,3aS,6aR,7S,9aR,10aS)-
- CBNumber
- CB0202198
- Molecular Formula
- C25H38O4
- Formula Weight
- 402.57
- MOL File
- 5601-74-1.mol
OPHIOBOLIN B Property
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- White to off-white solid.
Safety
- HS Code
- 2932190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 18432
- Product name
- Ophiobolin B
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $335
- Updated
- 2024/03/01
- Product number
- 18432
- Product name
- Ophiobolin B
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $1085
- Updated
- 2024/03/01
- Product number
- O669205
- Product name
- OphiobolinB
- Packaging
- 1mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- O7024-01
- Product name
- Ophiobolin B
- Packaging
- 1mg
- Price
- $523
- Updated
- 2021/12/16
- Product number
- 461592
- Product name
- Ophiobolin B
- Packaging
- 1mg
- Price
- $602
- Updated
- 2021/12/16
OPHIOBOLIN B Chemical Properties,Usage,Production
Uses
Calmodulin is a calcium-sensing protein that regulates a wide array of proteins involved in diverse cellular functions. Ophiobolin B is a sesterterpenoid fungal phytotoxin that binds and irreversibly antagonizes calmodulin, producing cytotoxic and antimicrobial effects. It induces apoptosis in chronic lymphocytic leukemia cells with an LC50 value of 2 nM and in different zygomycetes with MIC values ranging from 25-50 μg/ml.[Cayman Chemical]
Uses
Ophiobolin B is a fungal phytotoxin and inhibits calmodulin (a protein involved in calcium regulation). Ophiobolin B also exhibit antibacterial and antitumor activities.
Uses
Ophiobolin B is a minor member of a class of phytotoxic metabolites produced by Bipolaris and other genera of plant pathogenic fungi. Ophiobolin B acts by inhibiting calmodulin action in calcium regulation.
OPHIOBOLIN B Preparation Products And Raw materials
Raw materials
Preparation Products
OPHIOBOLIN B Suppliers
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