ChemicalBook > CAS DataBase List > OPHIOBOLIN B

OPHIOBOLIN B

Product Name
OPHIOBOLIN B
CAS No.
5601-74-1
Chemical Name
OPHIOBOLIN B
Synonyms
OPHIOBOLIN B;Cochliobolin B;Ophiobolin B (Cochliobolin B);Cochliobolin B, Zizanin B, Ophiobolsin A;3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al;Dicyclopenta[a,d]cyclooctene-4-carboxaldehyde, 7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1,7-dihydroxy-1,9a-dimethyl-3-oxo-, (1R,3aS,6aR,7S,9aR,10aS)-
CBNumber
CB0202198
Molecular Formula
C25H38O4
Formula Weight
402.57
MOL File
5601-74-1.mol
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OPHIOBOLIN B Property

storage temp. 
Store at -20°C
solubility 
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form 
White to off-white solid.
color 
White to off-white
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Safety

HS Code 
2932190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
18432
Product name
Ophiobolin B
Purity
≥95%
Packaging
1mg
Price
$335
Updated
2024/03/01
Cayman Chemical
Product number
18432
Product name
Ophiobolin B
Purity
≥95%
Packaging
5mg
Price
$1085
Updated
2024/03/01
TRC
Product number
O669205
Product name
OphiobolinB
Packaging
1mg
Price
$265
Updated
2021/12/16
Usbiological
Product number
O7024-01
Product name
Ophiobolin B
Packaging
1mg
Price
$523
Updated
2021/12/16
Usbiological
Product number
461592
Product name
Ophiobolin B
Packaging
1mg
Price
$602
Updated
2021/12/16
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OPHIOBOLIN B Chemical Properties,Usage,Production

Uses

Calmodulin is a calcium-sensing protein that regulates a wide array of proteins involved in diverse cellular functions. Ophiobolin B is a sesterterpenoid fungal phytotoxin that binds and irreversibly antagonizes calmodulin, producing cytotoxic and antimicrobial effects. It induces apoptosis in chronic lymphocytic leukemia cells with an LC50 value of 2 nM and in different zygomycetes with MIC values ranging from 25-50 μg/ml.[Cayman Chemical]

Uses

Ophiobolin B is a fungal phytotoxin and inhibits calmodulin (a protein involved in calcium regulation). Ophiobolin B also exhibit antibacterial and antitumor activities.

Uses

Ophiobolin B is a minor member of a class of phytotoxic metabolites produced by Bipolaris and other genera of plant pathogenic fungi. Ophiobolin B acts by inhibiting calmodulin action in calcium regulation.

OPHIOBOLIN B Preparation Products And Raw materials

Raw materials

Preparation Products

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OPHIOBOLIN B Suppliers

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5601-74-1, OPHIOBOLIN BRelated Search:

OLIGOMYCIN B PATULIN OPHIOBOLIN A PAXILLINE Parthenolide ECHINOCANDIN B 7-(5-amino-5-carboxyvaleramido)cephalosporanic acid OPHIOBOLIN B

  • OPHIOBOLIN B
  • 3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al
  • Cochliobolin B
  • Cochliobolin B, Zizanin B, Ophiobolsin A
  • Dicyclopenta[a,d]cyclooctene-4-carboxaldehyde, 7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1,7-dihydroxy-1,9a-dimethyl-3-oxo-, (1R,3aS,6aR,7S,9aR,10aS)-
  • Ophiobolin B (Cochliobolin B)
  • 5601-74-1