ChemicalBook > CAS DataBase List > P-nitrophenyl butyrate

P-nitrophenyl butyrate

Product Name
P-nitrophenyl butyrate
CAS No.
2635-84-9
Chemical Name
P-nitrophenyl butyrate
Synonyms
4-Nitrophenol butyrate;P-NITROPHENYL BUTYRATE;4-NITROPHENYL BUTYRATE;PARA-NITROPHENYLBUTYRATE;(4-nitrophenyl) butanoate;4-Nitrophenyl butyrate >=98%;BUTYRIC ACID 4-NITROPHENYL ESTER;Butanoic acid p-nitrophenyl ester;Butanoic acid, 4-nitrophenyl ester;p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester
CBNumber
CB0202840
Molecular Formula
C10H11NO4
Formula Weight
209.2
MOL File
2635-84-9.mol
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P-nitrophenyl butyrate Property

Boiling point:
184-185 °C
Density 
1.19 g/mL at 20 °C(lit.)
storage temp. 
-20°C
solubility 
chloroform: 0.1 g/mL, clear, faintly yellow
form 
A neat oil
color 
Colorless to light yellow
BRN 
1879729
InChIKey
DVDUMIQZEUTAGK-UHFFFAOYSA-N
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Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
WGK Germany 
3
HS Code 
29156000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N9876
Product name
4-Nitrophenyl butyrate
Purity
≥98%
Packaging
1g
Price
$77.6
Updated
2024/03/01
Sigma-Aldrich
Product number
N9876
Product name
4-Nitrophenyl butyrate
Purity
≥98%
Packaging
5g
Price
$276
Updated
2024/03/01
Cayman Chemical
Product number
25439
Product name
4-Nitrophenyl Butyrate
Purity
≥95%
Packaging
1g
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
25439
Product name
4-Nitrophenyl Butyrate
Purity
≥95%
Packaging
5g
Price
$202
Updated
2024/03/01
Sigma-Aldrich
Product number
N9876
Product name
4-Nitrophenyl butyrate
Purity
≥98%
Packaging
10g
Price
$465
Updated
2024/03/01
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P-nitrophenyl butyrate Chemical Properties,Usage,Production

Description

P-nitrophenyl butyrate also kown as 4-nitrophenyl butyrate, is a probe for lipase activity. It is hydrolyzed by lipase in the water ambient condition, giving rise to p-nitrophenol and butyric acid. P-nitrophenol actually occurs in the anionic form, p-nitrophenolate, giving a yellowish coloration and absorbing light at 410 nm in an alkaline buffer such as Tris-HCl pH 7.5.

Uses

4-Nitrophenyl butyrate is a substrate for esterase, and lipase enzyme. Hydrolysis of 4-nitrophenyl butyrate by these enzymes releases the chromophore, 4-nitrophenolate which is spectrophotometrically analysed at 415 nm.

Definition

ChEBI: P-nitrophenyl butyrate is a butyrate ester resulting from the formal condensation of the hydroxy group of 4-nitrophenol with the carboxy group of butyric acid. It is a butyrate ester and a C-nitro compound. It is functionally related to a 4-nitrophenol.

References

[1] POHANKA M. Biosensors and Bioassays Based on Lipases, Principles and Applications, a Review.[J]. Molecules, 2019. DOI:10.3390/molecules24030616.
[2] WENTING SHANG. Enzymatic hydrolysis of p-nitrophenyl butyrate in CO2-based micelle systems[J]. Journal of chemical technology and biotechnology, 2013, 89 9: 1324-1329. DOI:10.1002/jctb.4246.
[3] SIGRUN H. STERRI Frode F Bj?rn A Johnsen. A radiochemical assay method for carboxylesterase, and comparison of enzyme activity towards the substrates methyl [1-14C] butyrate and 4-nitrophenyl butyrate[J]. Biochemical pharmacology, 1985, 34 15: Pages 2779-2785. DOI:10.1016/0006-2952(85)90579-9.
[4] BISHNU PRASAD PANDEY. Bergenia pacumbis from Nepal, an astonishing enzymes inhibitor.[J]. BMC Complementary Medicine and Therapies, 2020: 198. DOI:10.1186/s12906-020-02989-2.

P-nitrophenyl butyrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from P-nitrophenyl butyrate manufacturers

Career Henan Chemical Co
Product
P-NITROPHENYL BUTYRATE 2635-84-9
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2019-12-31

2635-84-9, P-nitrophenyl butyrateRelated Search:


  • 4-Nitrophenyl butyrate,p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester
  • 4-NITROPHENYL BUTYRATE
  • P-NITROPHENYL BUTYRATE
  • Butanoic acid, 4-nitrophenyl ester
  • PARA-NITROPHENYLBUTYRATE
  • p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester
  • 4-Nitrophenol butyrate
  • Butanoic acid p-nitrophenyl ester
  • BUTYRIC ACID 4-NITROPHENYL ESTER
  • (4-nitrophenyl) butanoate
  • 4-Nitrophenyl butyrate >=98%
  • 2635-84-9
  • C10H11N1O4
  • Lipids
  • Chromogen
  • Enzyme Substrate
  • Fatty Acids
  • Biochemicals and Reagents
  • BioChemical