ChemicalBook > CAS DataBase List > Triptonide

Triptonide

Product Name: Triptonide
CAS No.: 38647-11-9
Chemical Name: Triptonide
Synonyms: PG 492;Triptonid;NSC 165677;TRIPTONIDE;2'',3'':6,7;()-Triptonide;Triptonide-RM;(-)-Triptonide;Triptonide USP/EP/BP;Triheptanoin Impurity 1
CBNumber: CB0205245
Molecular Formula: C20H22O6
Formula Weight: 358.39
MOL File: 38647-11-9.mol

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Triptonide Property

Melting point:: 251～252℃
Boiling point:: 581.1±50.0 °C(Predicted)
Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Dichloromethane (Slightly), Methanol (Slightly)
form: Solid
color: Off-White to Pale Beige
InChIKey: SWOVVKGLGOOUKI-PBIZPCRONA-N
SMILES: C[C@]12CCC3C(=O)OCC=3[C@]1([H])C[C@@H]1O[C@]31C([C@@]1(C(C)C)O[C@H]1[C@@H]1O[C@]231)=O |&1:1,10,13,15,17,22,23,25,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89812
Product name: Triptonide
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $515
Updated: 2025/07/31

Sigma-Aldrich

Product number: SMB00325
Product name: Triptonide
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $462
Updated: 2023/01/07

Sigma-Aldrich

Product number: SMB00325
Product name: Triptonide
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $1580
Updated: 2022/05/15

Cayman Chemical

Product number: 29156
Product name: (−)-Triptonide
Packaging: 1mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 29156
Product name: (−)-Triptonide
Packaging: 50mg
Price: $1189
Updated: 2024/03/01

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Triptonide Chemical Properties,Usage,Production

Chemical Properties

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Tripterygium wilfordii.

Uses

Triptonide is a Triptolide (T815600) analogue used in the preparation of cytotoxic fluorinated Triptolide.

Definition

ChEBI: Triptonide is a diterpene triepoxide that is triptobenzene K in which the acylhydroquinone moiety has undergone oxidation to the corresponding triepoxyketone derivative. It has been isolated from the roots of Tripterygium wilfordii. It has a role as an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent. It is a cyclic ketone, an organic heteroheptacyclic compound, a diterpene triepoxide and a butenolide.

in vivo

Triptonide (5 mg/kg; i.p.; daily; for 34 days) exerts a strong anti-lymphoma effect in mice^[2].

Animal Model:	Eight-week-old female NOD/SCID mice (18-22 g), with 3 x 10⁷ Raji cells xenograft^[2]
Dosage:	5 mg/kg
Administration:	Intraperitoneal injection, daily, for 34 days
Result:	Potently inhibited lymphoma cell growth and tumorigenic capability.

target

ERK | IL Receptor | GSK-3 | p38MAPK | Wnt/β-catenin

Triptonide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Triptonide manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Triptonide 38647-11-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Wuhan Boyuan Import & Export Co., LTD

Product: Triptonide 38647-11-9
Price: US $50.00/KG
Min. Order: 1KG
Purity: 99.9
Supply Ability: 200
Release date: 2023-02-15

Wuhan Boyuan Import & Export Co., LTD

Product: Triptonide
Price: US $50.00/KG
Min. Order: 10KG
Purity: 99.50%
Supply Ability: 1000kg
Release date: 2023-04-06

38647-11-9, TriptonideRelated Search:

Isopropyl alcohol Triptolide ISOPROPYL LAURATE Isopropyl acetate WILFORLIDE A Celastrol cicrotoic acid 1,2,3,4-DIEPOXYBUTANE 2-ETHOXYCYCLOHEXANONE Isobutyroin 1,3-Butadiene diepoxide 2,4-DIMETHYL-2-PENTENOIC ACID Methyl 1-cyclohexene-1-carboxylate CIS-4-TERT-BUTYLCYCLOHEXANOL Pinacol (-)-alpha-Terpineol Wilforlide (-)-DIHYDROCARVEOL

TRIPTONIDE

TRIPTONIDE(PRIMARY STANDARD)

NSC 165677

PG 492

(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-6a-Isopropyl-8b-methyl-3b,4,4a,7a,7b,8b,9,10-octahydrotrisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione

14-Deoxy-14-oxotriptolide

Triptolide,14-deoxy-14-oxo

Triptonide, 98%, from Peucedanum praeruptorum Dunn

Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione, 3b,4,4a,7a,7b,8b,9,10-octahydro-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-

Triptonide USP/EP/BP

(5bS,6aS,7aS,8aS,9aS,9bS,10aS,10bS)-8a-Isopropyl-10b-methyl-1,5b,6,6a,8a,9a,9b,10b-octahydrotris(oxireno)[2',3':4b,5

2''',3''':8a,9]phenanthro[1,2-c]furan-3,8(2H,5H)-dione

TIANFUCHEM--38647-11-9--High purity Triptonide factory price

2'',3'':6,7

Triptonid

(-)-Triptonide

()-Triptonide

Triheptanoin Impurity 1

Triptonide-RM

Triptonide, 10 mM in DMSO

38647-11-9

C20H22O6

Heterocycles

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract