ChemicalBook > CAS DataBase List > 2-ETHOXY-4,6-DICHLOROPYRIMIDINE

2-ETHOXY-4,6-DICHLOROPYRIMIDINE

Application

Product Name: 2-ETHOXY-4,6-DICHLOROPYRIMIDINE
CAS No.: 40758-65-4
Chemical Name: 2-ETHOXY-4,6-DICHLOROPYRIMIDINE
Synonyms: 4,6-DICHLORO-2-ETHOXYPYRIMIDINE;2-ETHOXY-4,6-DICHLOROPYRIMIDINE;Pyrimidine, 4,6-dichloro-2-ethoxy-
CBNumber: CB0208170
Molecular Formula: C6H6Cl2N2O
Formula Weight: 193.03
MOL File: 40758-65-4.mol

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2-ETHOXY-4,6-DICHLOROPYRIMIDINE Property

Boiling point:: 283.5±43.0 °C(Predicted)
Density: 1.375±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -4.46±0.30(Predicted)
CAS DataBase Reference: 40758-65-4(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: E940233
Product name: 2-Ethoxy-4,6-dichloropyrimidine
Packaging: 100mg
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: W6132
Product name: 2-Ethoxy-4,6-dichloropyrimidine
Packaging: 5g
Price: $1388
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0049704
Product name: 2-ETHOXY-4,6-DICHLOROPYRIMIDINE
Purity: 95.00%
Packaging: 100G
Price: $4446.75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0049704
Product name: 2-ETHOXY-4,6-DICHLOROPYRIMIDINE
Purity: 95.00%
Packaging: 250G
Price: $7738.5
Updated: 2021/12/16

Ambeed

Product number: A399005
Product name: 2-Ethoxy-4,6-dichloropyrimidine
Purity: 98%
Packaging: 250mg
Price: $84
Updated: 2021/12/16

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2-ETHOXY-4,6-DICHLOROPYRIMIDINE Chemical Properties,Usage,Production

Application

2-Ethoxy-4,6-dichloropyrimidine is an important heterocyclic pesticide and pharmaceutical intermediate. It can be used to synthesize highly effective herbicides containing triazole pyrimidine rings, such as dichlorvos and chlorpyrifos; it can also be used to synthesize certain antibiotics. Therefore, 2-ethoxy-4,6-dichloropyrimidine has broad application prospects in organic synthesis, pharmaceuticals, and pesticides.

Synthesis

141-52-6

4489-34-3

40758-65-4

To a 500 mL reaction flask equipped with a stirrer and thermometer was added 43.5 g of 2-methylsulfonyl-4,6-dichloropyrimidine (0.19 mol) and 90 g of ethanol and stirred at room temperature. The reaction mixture was then cooled to 0 °C and 130 g of sodium ethanol solution (0.38 mol) at a concentration of 20 wt% was slowly added dropwise. Upon completion of the reaction, the reaction was terminated by sampling and analysis to confirm that the feedstock content was less than 1%. After adjusting the reaction system to neutral pH, a small amount of acetic acid was added and ethanol was recovered under reduced pressure. Subsequently, dichloromethane was added, the solvent was evaporated and water was added to separate the organic layer. The organic layer was washed once with water and the first solvent was recovered. 35.2 g of 2-ethoxy-4,6-dichloropyrimidine was obtained in 95.2% yield and 96.5% purity (HPLC analysis) by distillation under reduced pressure until no liquid was exuded.

Toxics Screening Level

The ITSL is being set at the default value of 0.1 μg/m3 with annual averaging.

References

[1] Patent: CN106866547, 2017, A. Location in patent: Paragraph 0021; 0022

2-ETHOXY-4,6-DICHLOROPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-ETHOXY-4,6-DICHLOROPYRIMIDINE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Ethoxy-4,6-dichloropyrimidine 40758-65-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-28

Jiangsu Liyang Kunlun Biological Technology Co., Ltd.

Product: 2-ethoxy-4,6-dichloropyrimidine 40758-65-4
Price: US $0.00/kg
Min. Order: 1000kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2025-03-18

Hebei Yanxi Chemical Co., Ltd.

Product: 2-Ethoxy-4,6-dichloropyrimidine 40758-65-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: GC 90.0%
Supply Ability: 20tons
Release date: 2023-09-08

40758-65-4, 2-ETHOXY-4,6-DICHLOROPYRIMIDINERelated Search:

Magnesium hydroxide Diphenhydramine Sulfadiazine Pyrimidine Ferric sulfate 4,6-Dichloropyrimidine 2-ETHOXY-4,6-DICHLOROPYRIMIDINE 2-Methoxy-4,6-dichloropyrimidine Pyrimidine, 4-chloro-2-methoxy- (9CI)

2-ETHOXY-4,6-DICHLOROPYRIMIDINE

4,6-DICHLORO-2-ETHOXYPYRIMIDINE

Pyrimidine, 4,6-dichloro-2-ethoxy-

40758-65-4

C6H6N2OCl2

pyrimidine

Heterocycle-Pyrimidine series