ChemicalBook > CAS DataBase List > 2-Methoxy-4,6-dichloropyrimidine

2-Methoxy-4,6-dichloropyrimidine

Product Name
2-Methoxy-4,6-dichloropyrimidine
CAS No.
1074-40-4
Chemical Name
2-Methoxy-4,6-dichloropyrimidine
Synonyms
4.6-DICHLORO-2-METHOXYPYRIMIDIN;2-methoxy-4,6-dichloropyrimidine;2-Methoxy-4,6-dichloropyriMidinee;4,6-DICHLORO-2-METHOXY-PYRIMIDINE;Pyrimidine, 4,6-dichloro-2-methoxy-;2-Methoxy-4,6-dichloropyrimidine ISO 9001:2015 REACH;4,6-Dichloro-2-methoxy-1,3-diazine, 4,6-Dichloropyrimidin-2-yl methyl ether
CBNumber
CB5127115
Molecular Formula
C5H4Cl2N2O
Formula Weight
179
MOL File
1074-40-4.mol
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2-Methoxy-4,6-dichloropyrimidine Property

Melting point:
59-60°C
Boiling point:
105°C (11 Torr)
Density 
1.446
Flash point:
119°C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Chloroform, Methanol
pka
-4.52±0.30(Predicted)
form 
Solid
color 
Pale Yellow
InChI
InChI=1S/C5H4Cl2N2O/c1-10-5-8-3(6)2-4(7)9-5/h2H,1H3
InChIKey
WDELVDLDINRUQF-UHFFFAOYSA-N
SMILES
C1(OC)=NC(Cl)=CC(Cl)=N1
CAS DataBase Reference
1074-40-4(CAS DataBase Reference)
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
D435280
Product name
4,6-Dichloro-2-methoxypyrimidine
Packaging
10g
Price
$300
Updated
2021/12/16
Matrix Scientific
Product number
073390
Product name
4,6-Dichloro-2-methoxypyrimidine
Purity
95+%
Packaging
1g
Price
$370
Updated
2021/12/16
AK Scientific
Product number
B867
Product name
4,6-Dichloro-2-methoxypyrimidine
Packaging
25g
Price
$411
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21617
Product name
4,6-Dichloro-2-methoxypyrimidine
Packaging
250mg
Price
$157.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21617
Product name
4,6-Dichloro-2-methoxypyrimidine
Packaging
500mg
Price
$290
Updated
2021/12/16
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2-Methoxy-4,6-dichloropyrimidine Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Synthesis

1758-98-1

1074-40-4

Step 2: Synthesis of 4,6-dichloro-2-methoxypyrimidine; 2.25 g (7.92 mmol) of 4,6-dihydroxy-2-methoxypyrimidine and 10.0 mL (108.92 mmol) of phosphorus trichloride were mixed and the reaction was heated to reflux for 2 hours. Upon completion of the reaction, the reaction mixture was slowly poured into pre-cooled alkaline ice water and the pH was adjusted to alkaline with sodium hydroxide solution. Subsequently, the aqueous phase was extracted with dichloromethane. The organic phase was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. A product of 0.20 g was obtained in 14% yield. The product was analyzed by ESI-MS showing m/z = 179 ([M + H]+) and an HPLC retention time (Method B) of 1.38 min.

Toxics Screening Level

Due to a lack of available toxicity information the ITSL is being set at the default value of 0.1 μg/m3 with annual averaging, based on R232(1)(i).

References

[1] Patent: WO2007/65940, 2007, A1. Location in patent: Page/Page column 49-50
[2] Patent: US2012/88755, 2012, A1. Location in patent: Page/Page column 67

2-Methoxy-4,6-dichloropyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Methoxy-4,6-dichloropyrimidine Suppliers

Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
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sales@coolpharm.com
Country
China
ProdList
12878
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Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
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tongtf110@sina.com
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China
ProdList
993
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62
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
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sales@boylechem.com
Country
China
ProdList
2208
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
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Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
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2355560935@qq.com
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China
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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isenchem@163.com
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China
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Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
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sales@chemreagents.com
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United States
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Shanghai Hanhong Scientific Co.,Ltd.
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China
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Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
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shchemsky@sina.com
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China
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32321
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View Lastest Price from 2-Methoxy-4,6-dichloropyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Methoxy-4,6-dichloropyrimidine 1074-40-4
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-13
Career Henan Chemical Co
Product
2-Methoxy-4,6-dichloropyrimidine 1074-40-4
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-01

1074-40-4, 2-Methoxy-4,6-dichloropyrimidineRelated Search:


  • 2-methoxy-4,6-dichloropyrimidine
  • 4,6-DICHLORO-2-METHOXY-PYRIMIDINE
  • Pyrimidine, 4,6-dichloro-2-methoxy-
  • 4.6-DICHLORO-2-METHOXYPYRIMIDIN
  • 2-Methoxy-4,6-dichloropyriMidinee
  • 4,6-Dichloro-2-methoxy-1,3-diazine, 4,6-Dichloropyrimidin-2-yl methyl ether
  • 2-Methoxy-4,6-dichloropyrimidine ISO 9001:2015 REACH
  • 1074-40-4
  • Heterocycle-Pyrimidine series
  • Heterocyclic Compounds
  • Heterocycles