2-Methoxy-4,6-dichloropyrimidine
- Product Name
- 2-Methoxy-4,6-dichloropyrimidine
- CAS No.
- 1074-40-4
- Chemical Name
- 2-Methoxy-4,6-dichloropyrimidine
- Synonyms
- 4.6-DICHLORO-2-METHOXYPYRIMIDIN;2-methoxy-4,6-dichloropyrimidine;2-Methoxy-4,6-dichloropyriMidinee;4,6-DICHLORO-2-METHOXY-PYRIMIDINE;Pyrimidine, 4,6-dichloro-2-methoxy-;2-Methoxy-4,6-dichloropyrimidine ISO 9001:2015 REACH;4,6-Dichloro-2-methoxy-1,3-diazine, 4,6-Dichloropyrimidin-2-yl methyl ether
- CBNumber
- CB5127115
- Molecular Formula
- C5H4Cl2N2O
- Formula Weight
- 179
- MOL File
- 1074-40-4.mol
2-Methoxy-4,6-dichloropyrimidine Property
- Melting point:
- 59-60°C
- Boiling point:
- 105°C (11 Torr)
- Density
- 1.446
- Flash point:
- 119°C
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Chloroform, Methanol
- pka
- -4.52±0.30(Predicted)
- form
- Solid
- color
- Pale Yellow
- InChI
- InChI=1S/C5H4Cl2N2O/c1-10-5-8-3(6)2-4(7)9-5/h2H,1H3
- InChIKey
- WDELVDLDINRUQF-UHFFFAOYSA-N
- SMILES
- C1(OC)=NC(Cl)=CC(Cl)=N1
- CAS DataBase Reference
- 1074-40-4(CAS DataBase Reference)
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- D435280
- Product name
- 4,6-Dichloro-2-methoxypyrimidine
- Packaging
- 10g
- Price
- $300
- Updated
- 2021/12/16
- Product number
- 073390
- Product name
- 4,6-Dichloro-2-methoxypyrimidine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $370
- Updated
- 2021/12/16
- Product number
- B867
- Product name
- 4,6-Dichloro-2-methoxypyrimidine
- Packaging
- 25g
- Price
- $411
- Updated
- 2021/12/16
- Product number
- FD21617
- Product name
- 4,6-Dichloro-2-methoxypyrimidine
- Packaging
- 250mg
- Price
- $157.5
- Updated
- 2021/12/16
- Product number
- FD21617
- Product name
- 4,6-Dichloro-2-methoxypyrimidine
- Packaging
- 500mg
- Price
- $290
- Updated
- 2021/12/16
2-Methoxy-4,6-dichloropyrimidine Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Solid
Synthesis
1758-98-1
1074-40-4
Step 2: Synthesis of 4,6-dichloro-2-methoxypyrimidine; 2.25 g (7.92 mmol) of 4,6-dihydroxy-2-methoxypyrimidine and 10.0 mL (108.92 mmol) of phosphorus trichloride were mixed and the reaction was heated to reflux for 2 hours. Upon completion of the reaction, the reaction mixture was slowly poured into pre-cooled alkaline ice water and the pH was adjusted to alkaline with sodium hydroxide solution. Subsequently, the aqueous phase was extracted with dichloromethane. The organic phase was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. A product of 0.20 g was obtained in 14% yield. The product was analyzed by ESI-MS showing m/z = 179 ([M + H]+) and an HPLC retention time (Method B) of 1.38 min.
Toxics Screening Level
Due to a lack of available toxicity information the ITSL is being set at the default value of 0.1 μg/m3 with annual averaging, based on R232(1)(i).
References
[1] Patent: WO2007/65940, 2007, A1. Location in patent: Page/Page column 49-50
[2] Patent: US2012/88755, 2012, A1. Location in patent: Page/Page column 67
2-Methoxy-4,6-dichloropyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Methoxy-4,6-dichloropyrimidine manufacturers
- Product
- 2-Methoxy-4,6-dichloropyrimidine 1074-40-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-13
- Product
- 2-Methoxy-4,6-dichloropyrimidine 1074-40-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-01