ChemicalBook > CAS DataBase List > (S)-(-)-2-Methyl-2-propanesulfinamide
(S)-(-)-2-Methyl-2-propanesulfinamide
Description- Product Name
- (S)-(-)-2-Methyl-2-propanesulfinamide
- CAS No.
- 343338-28-3
- Chemical Name
- (S)-(-)-2-Methyl-2-propanesulfinamide
- Synonyms
- (S)-2-METHYLPROPANE-2-SULFINAMIDE;TERT-BUTYL SULFINAMIDE;(S)-(-)-T-BUTYLSULFINAMIDE;S-BSN;finamide;Suprabasin;S-tert-butylsulfonamide;S- tert butyl sulfenaMide;Brilanestrant Impurity 10;(S)-(-)-TERT-BUTYLSULFINAMIDE
- CBNumber
- CB0209955
- Molecular Formula
- C4H11NOS
- Formula Weight
- 121.2
- MOL File
- 343338-28-3.mol
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(S)-(-)-2-Methyl-2-propanesulfinamide Property
- Melting point:
- 97-101 °C(lit.)
- alpha
- -4.5 º (c=1, CHCl3)
- Boiling point:
- 220.0±23.0 °C(Predicted)
- Density
- 1.124
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 10.11±0.50(Predicted)
- form
- Crystalline Powder
- color
- White
- optical activity
- [α]20/D 4.5°, c = 1 in chloroform
- Stability:
- store cold
- InChI
- InChI=1/C4H11NOS/c1-4(2,3)7(5)6/h5H2,1-3H3/t7-/s3
- InChIKey
- CESUXLKAADQNTB-SSDOTTSWSA-N
- SMILES
- CC(C)([S@@](N)=O)C |&1:3,r|
- CAS DataBase Reference
- 343338-28-3(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi,Xn,F
- Risk Statements
- 11-19-36/37-40
- Safety Statements
- 16-26-36/37-24/25
- WGK Germany
- 3
- Hazard Note
- Irritant/Keep Cold
- TSCA
- No
- HS Code
- 29309090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 513210
- Product name
- (S)-(?)-2-Methyl-2-propanesulfinamide
- Purity
- 97%
- Packaging
- 1g
- Price
- $50.82
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 513210
- Product name
- (S)-(?)-2-Methyl-2-propanesulfinamide
- Purity
- 97%
- Packaging
- 5g
- Price
- $228
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B2908
- Product name
- (S)-(-)-tert-Butylsulfinamide
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $50
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B2908
- Product name
- (S)-(-)-tert-Butylsulfinamide
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $175
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- H27115
- Product name
- (S)-(-)-2-Methyl-2-propanesulfinamide, 97%
- Packaging
- 1g
- Price
- $76.65
- Updated
- 2024/03/01
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(S)-(-)-2-Methyl-2-propanesulfinamide Chemical Properties,Usage,Production
Description
Acid labile protecting groups are important in organic synthesis. The tert‐butyl group is commonly used for protection of a large variety of functional groups, e.g., acids, alcohols, phenols, and sulfonamides. Among them, s-tert-butyl sulfonamide is a chiral ligand used in pharmaceutical compositions. P, n-sulfoxide imine ligands were synthesized by condensation of s-tert-butylsulfonamide with aldehydes and ketones, and they can be used for asymmetric hydrogenation of olefins under iridium catalysis.
Physical properties
white to light yellow crystal powder
Uses
(S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents. It may also be used to prepare (20E)-N-[t-butyl-(S)-sulfinyl]-3β-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the preparation of androgen receptor antagonists.
Uses
(S)-(-)-2-Methyl-2-propanesulfinamide is used in Suzuki reaction. It is also employed as a reagent for synthesizing chiral amines. It acts as a chiral auxiliary used in an asymmetric synthesis of trifluoroethylamines by conversion of trifluoroacetaldehyde to a chiral imine. It is also involved in the transformation of P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins. Further, it serves as a reagent for the preparation of chemicals and pharmaceutical intermediates.
(S)-(-)-2-Methyl-2-propanesulfinamide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (S)-(-)-2-Methyl-2-propanesulfinamide manufacturers
Hebei Zhuanglai Chemical Trading Co Ltd
- Product
- 2-methylpropane-2-sulfinamide 343338-28-3
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-11-18
Shanghai UCHEM Inc.
- Product
- (S)-(-)-2-Methyl-2-propanesulfinamide 343338-28-3
- Price
- US $10.00-90.00/g
- Min. Order
- 5g
- Purity
- 0.98
- Supply Ability
- 25kg
- Release date
- 2023-12-11
Hebei Weibang Biotechnology Co., Ltd
- Product
- (S)-(-)-2-Methyl-2-propanesulfinamide 343338-28-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-25
343338-28-3, (S)-(-)-2-Methyl-2-propanesulfinamideRelated Search:
N-BENZYLQUININIUM CHLORIDE
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N-ISOPROPYL-2-NITROBENZENESULPHONAMIDE