Description
ChemicalBook > CAS DataBase List > (S)-(-)-2-Methyl-2-propanesulfinamide

(S)-(-)-2-Methyl-2-propanesulfinamide

Description
Product Name
(S)-(-)-2-Methyl-2-propanesulfinamide
CAS No.
343338-28-3
Chemical Name
(S)-(-)-2-Methyl-2-propanesulfinamide
Synonyms
(S)-2-METHYLPROPANE-2-SULFINAMIDE;TERT-BUTYL SULFINAMIDE;(S)-(-)-T-BUTYLSULFINAMIDE;S-BSN;finamide;Suprabasin;S-tert-butylsulfonamide;S- tert butyl sulfenaMide;Brilanestrant Impurity 10;(S)-(-)-TERT-BUTYLSULFINAMIDE
CBNumber
CB0209955
Molecular Formula
C4H11NOS
Formula Weight
121.2
MOL File
343338-28-3.mol
More
Less

(S)-(-)-2-Methyl-2-propanesulfinamide Property

Melting point:
97-101 °C(lit.)
alpha 
-4.5 º (c=1, CHCl3)
Boiling point:
220.0±23.0 °C(Predicted)
Density 
1.124
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
10.11±0.50(Predicted)
form 
Crystalline Powder
color 
White
optical activity
[α]20/D 4.5°, c = 1 in chloroform
Stability:
store cold
InChI
InChI=1/C4H11NOS/c1-4(2,3)7(5)6/h5H2,1-3H3/t7-/s3
InChIKey
CESUXLKAADQNTB-SSDOTTSWSA-N
SMILES
CC(C)([S@@](N)=O)C |&1:3,r|
CAS DataBase Reference
343338-28-3(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,Xn,F
Risk Statements 
11-19-36/37-40
Safety Statements 
16-26-36/37-24/25
WGK Germany 
3
Hazard Note 
Irritant/Keep Cold
TSCA 
No
HS Code 
29309090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
513210
Product name
(S)-(?)-2-Methyl-2-propanesulfinamide
Purity
97%
Packaging
1g
Price
$50.82
Updated
2024/03/01
Sigma-Aldrich
Product number
513210
Product name
(S)-(?)-2-Methyl-2-propanesulfinamide
Purity
97%
Packaging
5g
Price
$228
Updated
2024/03/01
TCI Chemical
Product number
B2908
Product name
(S)-(-)-tert-Butylsulfinamide
Purity
>98.0%(GC)
Packaging
1g
Price
$50
Updated
2024/03/01
TCI Chemical
Product number
B2908
Product name
(S)-(-)-tert-Butylsulfinamide
Purity
>98.0%(GC)
Packaging
5g
Price
$175
Updated
2024/03/01
Alfa Aesar
Product number
H27115
Product name
(S)-(-)-2-Methyl-2-propanesulfinamide, 97%
Packaging
1g
Price
$76.65
Updated
2024/03/01
More
Less

(S)-(-)-2-Methyl-2-propanesulfinamide Chemical Properties,Usage,Production

Description

Acid labile protecting groups are important in organic synthesis. The tert‐butyl group is commonly used for protection of a large variety of functional groups, e.g., acids, alcohols, phenols, and sulfonamides. Among them, s-tert-butyl sulfonamide is a chiral ligand used in pharmaceutical compositions. P, n-sulfoxide imine ligands were synthesized by condensation of s-tert-butylsulfonamide with aldehydes and ketones, and they can be used for asymmetric hydrogenation of olefins under iridium catalysis.

Physical properties

white to light yellow crystal powder

Uses

(S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents. It may also be used to prepare (20E)-N-[t-butyl-(S)-sulfinyl]-3β-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the preparation of androgen receptor antagonists.

Uses

(S)-(-)-2-Methyl-2-propanesulfinamide is used in Suzuki reaction. It is also employed as a reagent for synthesizing chiral amines. It acts as a chiral auxiliary used in an asymmetric synthesis of trifluoroethylamines by conversion of trifluoroacetaldehyde to a chiral imine. It is also involved in the transformation of P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins. Further, it serves as a reagent for the preparation of chemicals and pharmaceutical intermediates.

(S)-(-)-2-Methyl-2-propanesulfinamide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(S)-(-)-2-Methyl-2-propanesulfinamide Suppliers

Americas 1 Belgium 2 Canada 3 China 358 Europe 3 France 2 Germany 4 India 11 Japan 1 Switzerland 1 United Kingdom 16 United States 56 Global 458
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
More
Less

View Lastest Price from (S)-(-)-2-Methyl-2-propanesulfinamide manufacturers

Shanghai UCHEM Inc.
Product
(S)-(-)-2-Methyl-2-propanesulfinamide 343338-28-3
Price
US $10.00-90.00/g
Min. Order
5g
Purity
0.98
Supply Ability
25kg
Release date
2023-12-11
Hebei Yanxi Chemical Co., Ltd.
Product
2-methylpropane-2-sulfinamide 343338-28-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100tons
Release date
2023-09-05
Hebei Guanlang Biotechnology Co., Ltd.
Product
(S)-(-)-2-Methyl-2-propanesulfinamide 343338-28-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-09-28

343338-28-3, (S)-(-)-2-Methyl-2-propanesulfinamideRelated Search:

N-BENZYLQUININIUM CHLORIDE TERT-BUTYLSULFONAMIDE (R)-(+)-2-METHYL-2-PROPANESULFINAMIDE,(R)-2-METHYL-2-PROPANESULFINAMIDE Trimethoprim tert-Butanol Silver sulfate Boric acid (R)-(+)-4-Isopropyl-2-oxazolidinone (R)-(-)-4-Phenyl-2-oxazolidinone (4S)-(-)-4-Isopropyl-2-oxazolidinone (R)-4-Benzyl-2-oxazolidinone (S)-4-Benzyl-2-oxazolidinone (S)-(+)-4-Phenyl-2-oxazolidinone Di-tert-butylphosphine Tri-tert-butylphosphine Thionyl chloride Triisopropyl borate N-ISOPROPYL-2-NITROBENZENESULPHONAMIDE

  • 2-METHYL-2-PROPANE-SULFINAMIDE(S-ISOMER)
  • (S)-tert-Butylsulfinamide, (>98.0% ee), 97+%
  • (S)-(-)-2-METHYL-2-PROPANESULPHINAMIDE
  • (S)-2-METHYLPROPANE-2-SULFINAMIDE
  • (S)-(-)-2-METHYL-PROPANE-2-SULFINIC ACID AMIDE
  • (S)-(-)-TERT-BUTYLSULFINAMIDE
  • (S)-(-)-TERT-BUTYL SULPHINAMIDE
  • (S)-(-)-T-BUTYLMETHYLSULFINAMIDE
  • (S)-(-)-2-Methylpropane-2-sulphinamide 98%
  • [S(S)]-2-Methyl-2-propanesulfinaMide
  • 2-PropanesulfinaMide, 2-Methyl-, [S(S)]-
  • S-BSN
  • S- tert butyl sulfenaMide
  • (S)-tert-Butylsulfinamide (S)-(-)-2-Methyl-2-propanesulfinamide
  • (S)-(?)-2-Methyl-2-propanesulfinamide solution
  • ANTI-SBSN (N-TERM) antibody produced in rabbit
  • Suprabasin
  • (S)-(-)-<i>tert</i>-Butylsulfinamide
  • (S)-(-)-2-Methyl-2-propanesulfinamide 97%
  • Amino(tert-butyl)sulfaniumolate
  • (S)-(-)-t-Butylsulfinamide, min. 97%
  • (S)-TERT-BUTANESULFINAMIDE / (S)-(-)-2-METHYL-2-P
  • (S)-(-)-2-Methyl-2-propanesulfimide
  • (S)-2-Methyl-2-propanesulfinamide,99%e.e.
  • S-tert-butylsulfonamide
  • (S)-(-)-T-BUTYLSULFINAMIDE
  • TERT-BUTYL SULFINAMIDE
  • (S)-(-)-t-Butylmethylsulfinamide,min.97%
  • (S)-(-)-tert-Butyl sulphinamide 98%
  • (S)-(-)-t-Butyl sulfinamide, 98% ee
  • (S)-TERT-BUTANESULFINAMIDE / (S)-(-)-2-METHYL-2-PROPANESULFINAMIDE
  • (S)-(-)-2-METHYL-2-PROPANESULFINAMIDE,98.5+%
  • (S)-TERT-BUTYLSULFINAMIDE,97+% (>98.0% EE)
  • (S)-(-)-t-Butylmethylsulfinamide, min. 97%
  • (S)-tert-Butylsulfinamide, (>98.0% ee)
  • (S)-(-)-2-Methyl-2-propanesulfinamide
  • (S)-Tert butane sulfonamide 98%
  • (S)-(-)-2-Methyl-2-propanesulfinaMide(S)-(-)-2-Methyl-2-propanesulfinaMide
  • finamide
  • (S)-(-)-tert-Butylsulfinamide &gt
  • (S)-(-)-tert-Butylsulfinamide, 98%, for synthesis
  • (S)-(-)-2-Methyl-2-propanesulfinamide USP/EP/BP
  • Brilanestrant Impurity 10
  • 343338-28-3
  • 343338-27-8
  • 343338-28-2
  • 3423338-28-3
  • C3H11CNOS
  • C4H9CH3SONH2
  • C4H11NOS
  • Organic Building Blocks
  • Sulfur-Based
  • Sulfur Compounds
  • Sulfonamides/Sulfinamides
  • Building Blocks
  • Asymmetric Synthesis
  • Chiral Auxiliaries
  • Asymmetric Synthesis