(R)-4-Benzyl-2-oxazolidinone

Product Name: (R)-4-Benzyl-2-oxazolidinone
CAS No.: 102029-44-7
Chemical Name: (R)-4-Benzyl-2-oxazolidinone
Synonyms: (R)-4-(PHENYLMETHYL)-2-OXAZOLIDINONE;RBOX;4-benzyl-2-0xazolidinone;(4R)-Phenylmethyl-2-oxazolidinone;R-BOZ;MLS00;TB-2044;TL806371;-2-oxazoL;(R)-4-BenzyL
CBNumber: CB7852611
Molecular Formula: C10H11NO2
Formula Weight: 177.2
MOL File: 102029-44-7.mol

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(R)-4-Benzyl-2-oxazolidinone Property

Melting point:: 88-90 °C
alpha: 62 º (C=1, CHCl3)
Boiling point:: 309.12°C (rough estimate)
Density: 1.1607 (rough estimate)
refractive index: 14.5 ° (C=5, MeOH)
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly)
pka: 12.78±0.40(Predicted)
form: Crystalline Powder
color: White to almost white
optical activity: [α]18/D +64°, c = 1 in chloroform
Water Solubility: Insoluble in water. Soluble in Chloroform.
Sensitive: Hygroscopic
BRN: 4782551
CAS DataBase Reference: 102029-44-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
F: 3-10
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 300977
Product name: (R)-4-Benzyl-2-oxazolidinone
Purity: 99%
Packaging: 5g
Price: $24.68
Updated: 2024/03/01

Sigma-Aldrich

Product number: 300977
Product name: (R)-4-Benzyl-2-oxazolidinone
Purity: 99%
Packaging: 1G
Price: $35.8
Updated: 2023/01/07

TCI Chemical

Product number: B1786
Product name: (R)-4-Benzyl-2-oxazolidinone
Purity: >98.0%(GC)
Packaging: 5g
Price: $92
Updated: 2024/03/01

TCI Chemical

Product number: B1786
Product name: (R)-4-Benzyl-2-oxazolidinone
Purity: >98.0%(GC)
Packaging: 25g
Price: $297
Updated: 2024/03/01

Alfa Aesar

Product number: A16770
Product name: (R)-(+)-4-Benzyl-2-oxazolidinone, 99%
Packaging: 1g
Price: $40.65
Updated: 2024/03/01

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(R)-4-Benzyl-2-oxazolidinone Chemical Properties,Usage,Production

Description

(R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It can be used in the preparation of enantiopure carbocyclic nucleosides, which act as a HIV protease inhibitor. It can also be used as a chiral auxiliary in the enantioselective synthesis of (2R, 2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids. Its end product includes asymmetric single isomeric drugs such as antitumor, anesthetic and entipasmodic products.

Chemical Properties

white to light yellow crystal powde

Uses

intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan

Uses

(R)-(+)-4-Benzyl-2-oxazolidinones are used in the enantioselective synthesis of beta-lactams and alpha-amino acids. End products can include asysmmetric single isomeric drugs of antitumor, anesthetic, antipasmodic products. Used in the synthesis of HIV protease inhibitors. An oxazolidinone used in chiral auxiliary asymetric synthesis.

References

http://www.sigmaaldrich.com/catalog/product/aldrich/300977? lang=en®ion=US
https://www.alfa.com/en/catalog/A16770/ Shieh, Wen Chung, et al. "Synthesis of enantiomerically enriched 4- piperidinylglycine." US, US 6670477B2. 2003.

(R)-4-Benzyl-2-oxazolidinone Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-4-Benzyl-2-oxazolidinone Suppliers

Americas 1 Belgium 2 Canada 5 China 407 Europe 4 France 2 Germany 4 India 18 Japan 6 Slovakia 1 South Korea 1 Switzerland 6 The Netherlands 1 United Kingdom 24 United States 70 Global 552

Shanghai Mixiu Chemical Co., Ltd.

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Beijing Donghualituo Techonlogy Development Co.,Ltd.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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View Lastest Price from (R)-4-Benzyl-2-oxazolidinone manufacturers

hebei hongtan Biotechnology Co., Ltd

Product: (R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000
Release date: 2024-03-22

Jinan Jianfeng Chemical Co., Ltd

Product: (R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 20ton
Release date: 2024-08-14

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 99%min
Supply Ability: 500kg
Release date: 2021-09-22

102029-44-7, (R)-4-Benzyl-2-oxazolidinoneRelated Search:

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(R)-4-BENZYL-2-OXAZOLIDINONE HPLC 99+%

(R)-4-BENZYL-2-OXAZOLIDINONE 98.0%

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(R)-(+)-4-BENZYL-2-OXAZOLIDINONE FOR SYN

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2-OXAZOLIDINONE, 4-PHENYL-, (4R)-

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RBOX

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<i>(R)</i>-(+)-4-Benzyl-2-oxazolidinone

(R)-4-BenzyL

(R)-4-Benzyl-2-oxazolidinone &gt

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(R)-4-Benzyl-2-oxazolidinone USP/EP/BP

(R)-4-Benzyl-2-oxazolidinone CAS No. 102029-44-7

MLS00

OJOFMLDBXPDXLQ-SECBINFHSA-N

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102029-44-7

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Chiral Building Blocks

Asymmetric Synthesis

Glycidyl Compounds, etc. (Chiral)

Chiral Auxiliaries

Oxazolidinone Derivatives

Asymmetric Synthesis