ChemicalBook > CAS DataBase List > (R)-4-Benzyl-2-oxazolidinone

(R)-4-Benzyl-2-oxazolidinone

Product Name
(R)-4-Benzyl-2-oxazolidinone
CAS No.
102029-44-7
Chemical Name
(R)-4-Benzyl-2-oxazolidinone
Synonyms
(R)-4-(PHENYLMETHYL)-2-OXAZOLIDINONE;RBOX;4-benzyl-2-0xazolidinone;(4R)-Phenylmethyl-2-oxazolidinone;R-BOZ;MLS00;TB-2044;TL806371;-2-oxazoL;(R)-4-BenzyL
CBNumber
CB7852611
Molecular Formula
C10H11NO2
Formula Weight
177.2
MOL File
102029-44-7.mol
More
Less

(R)-4-Benzyl-2-oxazolidinone Property

Melting point:
88-90 °C
alpha 
62 º (C=1, CHCl3)
Boiling point:
309.12°C (rough estimate)
Density 
1.1607 (rough estimate)
refractive index 
14.5 ° (C=5, MeOH)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly)
pka
12.78±0.40(Predicted)
form 
Crystalline Powder
color 
White to almost white
optical activity
[α]18/D +64°, c = 1 in chloroform
Water Solubility 
Insoluble in water. Soluble in Chloroform.
Sensitive 
Hygroscopic
BRN 
4782551
CAS DataBase Reference
102029-44-7(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
F 
3-10
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
300977
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
99%
Packaging
5g
Price
$24.68
Updated
2024/03/01
Sigma-Aldrich
Product number
300977
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
99%
Packaging
1G
Price
$35.8
Updated
2023/01/07
TCI Chemical
Product number
B1786
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
>98.0%(GC)
Packaging
5g
Price
$92
Updated
2024/03/01
TCI Chemical
Product number
B1786
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
>98.0%(GC)
Packaging
25g
Price
$297
Updated
2024/03/01
Alfa Aesar
Product number
A16770
Product name
(R)-(+)-4-Benzyl-2-oxazolidinone, 99%
Packaging
1g
Price
$40.65
Updated
2024/03/01
More
Less

(R)-4-Benzyl-2-oxazolidinone Chemical Properties,Usage,Production

Description

(R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It can be used in the preparation of enantiopure carbocyclic nucleosides, which act as a HIV protease inhibitor. It can also be used as a chiral auxiliary in the enantioselective synthesis of (2R, 2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids. Its end product includes asymmetric single isomeric drugs such as antitumor, anesthetic and entipasmodic products.

Chemical Properties

white to light yellow crystal powde

Uses

intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan

Uses

(R)-(+)-4-Benzyl-2-oxazolidinones are used in the enantioselective synthesis of beta-lactams and alpha-amino acids. End products can include asysmmetric single isomeric drugs of antitumor, anesthetic, antipasmodic products. Used in the synthesis of HIV protease inhibitors. An oxazolidinone used in chiral auxiliary asymetric synthesis.

References

http://www.sigmaaldrich.com/catalog/product/aldrich/300977? lang=en®ion=US
https://www.alfa.com/en/catalog/A16770/ Shieh, Wen Chung, et al. "Synthesis of enantiomerically enriched 4- piperidinylglycine." US, US 6670477B2. 2003.

(R)-4-Benzyl-2-oxazolidinone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-4-Benzyl-2-oxazolidinone Suppliers

Americas 1 Belgium 2 Canada 5 China 396 Europe 4 France 2 Germany 4 India 18 Japan 6 Slovakia 1 South Korea 1 Switzerland 6 The Netherlands 1 United Kingdom 24 United States 69 Global 540
Nanjing Gold Pharmaceutical Technology Co. Ltd.
Tel
025-84209270; 15905158493
Fax
025-84209270
Email
wgp@nanjing-pharmaceutical.com
Country
China
ProdList
63
Advantage
55
Shanghai Mixiu Chemical Co., Ltd.
Tel
18101936766
Fax
021-58583907
Email
eileen@shmychem.com
Country
China
ProdList
351
Advantage
55
NINGBO SYNTAME BIOTECH CO LTD
Tel
18668283131 座机0574-28802872
Email
sales@syntame.com
Country
China
ProdList
99
Advantage
58
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1686
Advantage
58
Jiangsu WNC Pharmaceutical Co.,Ltd
Tel
13951385330
Email
25541157@qq.com
Country
China
ProdList
16
Advantage
58
Shanghai Qiude Biochemical Engineering Co., Ltd
Tel
021-37285021 13472570865;
Fax
86-021-51714507
Email
info@pure-chiral.com
Country
China
ProdList
288
Advantage
64
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Beijing Donghualituo Techonlogy Development Co.,Ltd.
Tel
010-88425576
Fax
(+86)-10-88425546
Email
sales@dhltchem.com
Country
China
ProdList
793
Advantage
59
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
More
Less

View Lastest Price from (R)-4-Benzyl-2-oxazolidinone manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
(R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000
Release date
2024-03-22
Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
(R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99
Supply Ability
20tons
Release date
2024-02-06
R&D Scientific Inc.
Product
(R)-4-benzyl-2-oxazolidone 102029-44-7
Price
US $490.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
1500 Kg
Release date
2024-03-28

102029-44-7, (R)-4-Benzyl-2-oxazolidinoneRelated Search:

(-)-4-Benzyl-2-oxazolidinone,(S)-(-)-4-BENZYL-2-OXAZOLIDINONE,(S)-4-BENZYL-2-OXAZOLIDINONE,4-(S)-Benzyl-2-oxazolidinone,(S)-4-Benzyl-2-oxazolidinone, >99% ee (S)-(+)-4-Phenyl-2-oxazolidinone (N-CHLOROACETYL)-(4S)-BENZYL-2-OXAZOLIDINONE N-PROPIONYL-(4R)-BENZYL-2-OXAZOLIDINONE,N-3-PROPIONYL-(4R)-BENZYL-2-OXAZOLIDINONE (S)-4-(4'-Nitrobenzyl)-1,3-oxazolidine-2-one (R)-(+)-5,5-DIPHENYL-4-BENZYL-2-OXAZOLIDINONE (R)-4-Benzyl-2-oxazolidinone 4-(4-Hydrazinobenzyl)-2-oxazolidinone N-PROPIONYL-(4S)-BENZYL-2-OXAZOLIDINONE,N-3-PROPIONYL-(4S)-BENZYL-2-OXAZOLIDINONE S/R-4-BENZYL-2-OXAZOLIDINONE 2-Oxazolidone (R)-4-(4-AMINOMETHYL-BENZYL)-OXAZOLIDIN-2-ONE (3S,4R)-4-BENZYL-3-(3-METHYLPENTANOYL)-OXAZOLIDIN-2-ONE (N-ACETYL)-(4R)-BENZYL-2-OXAZOLIDINONE Z-D-Phenylalanine N-carboxyanhydride (R)-4-BENZYL-OXAZOLIDINE-2,5-DIONE (R)-4-BENZYL-3-(3-CYCLOPENTYL-PROPIONYL)-OXAZOLIDIN-2-ONE (R)-4-BENZYL-3-(3-CYCLOPROPYL-PROPIONYL)-OXAZOLIDIN-2-ONE

  • 4-benzyl-2-0xazolidinone
  • (R)-4-BENZYL-2-OXAZOLIDINONE HPLC 99+%
  • (R)-4-BENZYL-2-OXAZOLIDINONE 98.0%
  • (4R)-4-(Phenylmethyl)-1,3-oxazolidin-2-one
  • (4R)-4-(Phenylmethyl)-2-oxazolidinone
  • (4R)-Benzyloxazolidin-2-one
  • (4R)-Phenylmethyl-2-oxazolidinone
  • (R)-(+)-4-BENZYL-2-OXAZOLIDINONE FOR SYN
  • (R)-(+)-4-Benzyl-2-oxazolidinone≥ 99.5% (HPLC, Chiral purity)
  • R-BOZ
  • (4R)-4-Benzyl-2-oxo-1,3-oxazolidine, (4R)-4-(Phenylmethyl)-1,3-oxazolidin-2-one
  • (R)-4-Benzyl-2-oxazolidinone 99%
  • (R)-4-Benzyl-2-oxazolidinone, 99%, ee:>99%
  • (R)-4-Benzyl-2-oxazolidinone, >99% ee
  • (R)-4-Benzyl-2-oxazolidinone,99%,>99% ee
  • (R)-4-Benzyl-2-0xazolidinone
  • (R)-(+)-4-Benzyl-2-xazolidineone
  • (R)-4-Benzyl-2-oxazo
  • (R)-4-Benzyl-2-oxazolidinone,99%
  • (4R)-4-Benzyl-2-oxo-1,3-oxazolidine
  • 2-OXAZOLIDINONE, 4-(PHENYLMETHYL)-, (4R)-
  • 2-OXAZOLIDINONE, 4-PHENYL-, (4R)-
  • (4R)-4-BENZYL-1,3-OXAZOLIDIN-2-ONE
  • (4R)-4-BENZYLOXAZOLIDIN-2-ONE
  • (4R)-4-PHENYL-1,3-OXAZOLIDIN-2-ONE
  • (4R)-4-PHENYLOXAZOLIDIN-2-ONE
  • 4-R-BENZYL-2-OXAZOLIDINONE
  • (4R)-PHENYL-2-OXAZOLIDINONE
  • (R)-PH-OXAZOLIDINONE
  • RBOX
  • (R)-4-(PHENYLMETHYL)-2-OXAZOLIDINONE
  • (R)-4-BENZYL-OXAZOLIDIN-2-ONE
  • (R)-(+)-4-BENZYL-2-OXAZOLIDINONE
  • (R)-4-BENZYL-2-OXAZOLIDINONE
  • (R)-(+)-4-BENZYL-2-OXAZOLIDONE
  • <i>(R)</i>-(+)-4-Benzyl-2-oxazolidinone
  • (R)-4-BenzyL
  • (R)-4-Benzyl-2-oxazolidinone &gt
  • -2-oxazoL
  • (R)-4-Benzyl-2-oxazolidinone USP/EP/BP
  • (R)-4-Benzyl-2-oxazolidinone CAS No. 102029-44-7
  • MLS00
  • OJOFMLDBXPDXLQ-SECBINFHSA-N
  • TL806371
  • TB-2044
  • (R)-Solriamfetol Impurity 5
  • 102029-44-7
  • 102021-44-7
  • 99319-52-1
  • 102090-44-7
  • 1022029-44-7
  • 101029-44-7
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Glycidyl Compounds, etc. (Chiral)
  • Chiral Auxiliaries
  • Oxazolidinone Derivatives
  • Asymmetric Synthesis