2-Oxazolidone

Product Name: 2-Oxazolidone
CAS No.: 497-25-6
Chemical Name: 2-Oxazolidone
Synonyms: oxazolidin-2-one;Oxazolidine;2-OXAZOLIDINONE;Oxazolidone;NSC 35382;2-Oxazolinone;2-OXAZOLIDIONE;2-OX;2-OxazoL;NSC 38240
CBNumber: CB7141597
Molecular Formula: C3H5NO2
Formula Weight: 87.08
MOL File: 497-25-6.mol

More

Less

2-Oxazolidone Property

Melting point:: 83-87 °C(lit.)
Boiling point:: 220 °C48 mm Hg(lit.)
Density: 1.2736 (rough estimate)
refractive index: 1.4940 (estimate)
Flash point:: 220°C/48mm
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly, Heated), Methanol (Slightly)
pka: 12.78±0.20(Predicted)
form: Crystals or Powder
color: Off-white to yellow-beige
Water Solubility: Soluble in water.
BRN: 106251
InChI: 1S/C3H5NO2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
InChIKey: IZXIZTKNFFYFOF-UHFFFAOYSA-N
SMILES: O=C1NCCO1
CAS DataBase Reference: 497-25-6(CAS DataBase Reference)
NIST Chemistry Reference: Oxazolidin-2-one(497-25-6)
EPA Substance Registry System: 2-Oxazolidinone (497-25-6)

More

Less

Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36-43-40-36/37/38
Safety Statements: 26-36/37-37-36
WGK Germany: 3
RTECS: RQ2450000
TSCA: TSCA listed
HS Code: 29322980
Storage Class: 13 - Non Combustible Solids
Toxicity: TDLo orl-mus: 1000 mg/kg:ETA BCPCA62,168,59

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: O9409
Product name: 2-Oxazolidinone
Purity: 98%
Packaging: 5g
Price: $37.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: O9409
Product name: 2-Oxazolidinone
Purity: 98%
Packaging: 25g
Price: $49.9
Updated: 2025/07/31

TCI Chemical

Product number: O0188
Product name: 2-Oxazolidone
Purity: >98.0%(GC)
Packaging: 25g
Price: $29
Updated: 2025/07/31

TCI Chemical

Product number: O0188
Product name: 2-Oxazolidone
Purity: >98.0%(GC)
Packaging: 100g
Price: $90
Updated: 2025/07/31

Sigma-Aldrich

Product number: O9409
Product name: 2-Oxazolidinone
Purity: 98%
Packaging: 100g
Price: $124.45
Updated: 2025/07/31

More

Less

2-Oxazolidone Chemical Properties,Usage,Production

Chemical Properties

off-white to yellow-beige crystals or powder

Uses

An oxazole derivative used as an antibiotic. It is also used in the preparation of compounds with antitumor activity. A metabolite of Furazolidone (F864100).

Uses

As an oxazole derivative used as an antibiotic, 2-Oxazolidone is also used in the preparation of compounds with antitumor activity and as a metabolite of Furazolidone (F864100).

Definition

ChEBI: An oxazolidinone that is 1,3-oxazolidine with an oxo substituent at position 2.

Safety Profile

Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.

Synthesis

2-Oxazolidinone is synthesized by the following methods: 1) electrolytic cyclization and oxidation of hydroxyethyl formamide; 2) reaction of aminoethanol with CO2 gas; 3) reaction of epoxide with cyanuric acid or urea; 4) reaction of acrolein with isocyanate; 5) reaction of aziridine with CO2 gas; 6) reaction of ??-hydroxyethyl carbamate with urea; 7) reaction of aminoethanol with urea etc.

Purification Methods

Crystallise it from *benzene, dichloroethane, CHCl3 or EtOH. It is a cyclic urethane, and as such it is not very stable. [Katritzky et al. J Chem Soc Perkin II 145 1990, Beilstein 27 H 135, 27 II 259, 27 III/IV 2516.]

2-Oxazolidone Preparation Products And Raw materials

Raw materials

Monoethanolamine

Preparation Products

Lomustine N,N'-bis-(2-Chloroethyl)urea 3-AMINO-2-OXAZOLIDINONE Furazolidone

More

Less

2-Oxazolidone Suppliers

Americas 1 Belgium 3 Canada 2 China 251 Europe 2 Germany 9 India 7 Japan 4 Switzerland 2 Ukraine 1 United Kingdom 12 United States 44 Global 338

Ningbo Chemrio Chemtech Co,.Ltd.

Tel: 0574-27891269 18667892864
Email: frank.xiaodong@chemriotech.com
Country: China
ProdList: 3892
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9401
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Suzhou Highfine Biotech Co., Ltd

Tel: 0512-68417696 13962195629
Fax: 0512-68417696
Email: minhan.zhao@highfine.com
Country: China
ProdList: 475
Advantage: 75

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 11999
Advantage: 60

More

Less

View Lastest Price from 2-Oxazolidone manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Oxazolidone 497-25-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-11-13

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 2-Oxazolidone 497-25-6
Price: US $25.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-11

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Oxazolidone 497-25-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-23

497-25-6, 2-Oxazolidone Related Search:

Oxadixyl Bis(2-oxo-3-oxazolidinyl)phosphinic chloride 3-PHENYL-2-OXAZOLIDINONE 3-(2'-HYDROXYETHYL)-2-OXAZOLIDONE,N-Hydroxyethyl-2-oxazolidone 3-((5-Nitrofurylidene)amino)-2-oxazolidone,3-(5'-Nitrofurfuralamino)-2-oxazolidone,3-(5’-nitrofurfuralamino)-2-oxazolidon 5-CHLOROMETHYL-2-OXAZOLIDINONE (S)-(+)-4-PHENYL-2-OXAZOLIDONE (4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone (S)-(+)-4-Isopropyl-3-propionyl-2-oxazolidinone S-4-Isopropyl-2-oxazolidone 3-TRIMETHYLSILYL-2-OXAZOLIDONE 3-AMINO-2-OXAZOLIDINONE 5,5-Dimethyloxazolidine-2,4-dione (R)-(+)-4-BENZYL-2-OXAZOLIDONE 3-Methyl-2-oxazolidone 3-Acetyl-1-chlorocarbonyl-2-imidazolidone 5-methylthiomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidone N-PROPIONYL-(4S,5R)-4-METHYL- 5-PHENYL-2-OXAZOLIDINONE

2-Oxotetrahydro-1,3-oxazole

2-Oxazolinone

2-Oxazolidone,98%

2-Oxazolidone, 98% 100GR

2-Oxazolidone, 98% 25GR

2-Oxo-1,3-oxazolidine

NSC 35382

NSC 38240

2-Oxazolidinone≥ 99%(GC)

2H-oxazol-2-id-4-one

(2-hydroxyethyl)-carbamicacigamma-lactone

1,3-Oxazolidin-2-one

2-Oxazolidine

Carbamic acid, (2-hydroxyethyl)-, gamma-lactone

Oxazolidine

Oxazolidone

2-OX

2-OXAZOLIDONE

2-OXAZOLIDINONE

oxazolidin-2-one

2-Oxazolidinone,99%

2-OXAZOLIDIONE

(2-hydroxyethyl)-carbamic acid gamma-lactone

2-OXAZOLIDINONE 98%

2-OxazoL

2-Oxazolidone&gt

2-Oxazolidinone, 98%, for synthesis

Levetiracetam Impurity 45

2-Oxazolidinone (7CI, 8CI, 9CI, ACI)

(4S,4′S)-4,4′-[[4-(dimethylamino)butane-1,1-diyl]bis[[3-[2-(dimethylamino)ethyl]-1H-indole-2,5-diyl]methylene]]bis(1,3-oxazolidin-2-one)

497-25-6

495-25-6

C3H5NO2

Oxazolines/Oxazolidines

Heterocyclic Building Blocks

Building Blocks

Heterocyclic Building Blocks

Oxazolines/Oxazolidines

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Heterocyclic Compounds