ChemicalBook > CAS DataBase List > (R)-4-Benzyl-2-oxazolidinone

(R)-4-Benzyl-2-oxazolidinone

Product Name
(R)-4-Benzyl-2-oxazolidinone
CAS No.
102029-44-7
Chemical Name
(R)-4-Benzyl-2-oxazolidinone
Synonyms
(R)-4-(PHENYLMETHYL)-2-OXAZOLIDINONE;RBOX;4-benzyl-2-0xazolidinone;(4R)-Phenylmethyl-2-oxazolidinone;R-BOZ;MLS00;TB-2044;TL806371;-2-oxazoL;(R)-4-BenzyL
CBNumber
CB7852611
Molecular Formula
C10H11NO2
Formula Weight
177.2
MOL File
102029-44-7.mol
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(R)-4-Benzyl-2-oxazolidinone Property

Melting point:
88-90 °C
alpha 
62 º (C=1, CHCl3)
Boiling point:
309.12°C (rough estimate)
Density 
1.1607 (rough estimate)
refractive index 
14.5 ° (C=5, MeOH)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly)
pka
12.78±0.40(Predicted)
form 
Crystalline Powder
color 
White to almost white
optical activity
[α]18/D +64°, c = 1 in chloroform
Water Solubility 
Insoluble in water. Soluble in Chloroform.
Sensitive 
Hygroscopic
BRN 
4782551
CAS DataBase Reference
102029-44-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
F 
3-10
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
300977
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
99%
Packaging
5g
Price
$24.68
Updated
2024/03/01
Sigma-Aldrich
Product number
300977
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
99%
Packaging
1G
Price
$35.8
Updated
2023/01/07
TCI Chemical
Product number
B1786
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
>98.0%(GC)
Packaging
5g
Price
$92
Updated
2024/03/01
TCI Chemical
Product number
B1786
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
>98.0%(GC)
Packaging
25g
Price
$297
Updated
2024/03/01
Alfa Aesar
Product number
A16770
Product name
(R)-(+)-4-Benzyl-2-oxazolidinone, 99%
Packaging
1g
Price
$40.65
Updated
2024/03/01
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(R)-4-Benzyl-2-oxazolidinone Chemical Properties,Usage,Production

Description

(R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It can be used in the preparation of enantiopure carbocyclic nucleosides, which act as a HIV protease inhibitor. It can also be used as a chiral auxiliary in the enantioselective synthesis of (2R, 2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids. Its end product includes asymmetric single isomeric drugs such as antitumor, anesthetic and entipasmodic products.

Chemical Properties

white to light yellow crystal powde

Uses

intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan

Uses

(R)-(+)-4-Benzyl-2-oxazolidinones are used in the enantioselective synthesis of beta-lactams and alpha-amino acids. End products can include asysmmetric single isomeric drugs of antitumor, anesthetic, antipasmodic products. Used in the synthesis of HIV protease inhibitors. An oxazolidinone used in chiral auxiliary asymetric synthesis.

References

http://www.sigmaaldrich.com/catalog/product/aldrich/300977? lang=en®ion=US
https://www.alfa.com/en/catalog/A16770/ Shieh, Wen Chung, et al. "Synthesis of enantiomerically enriched 4- piperidinylglycine." US, US 6670477B2. 2003.

(R)-4-Benzyl-2-oxazolidinone Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-4-Benzyl-2-oxazolidinone Suppliers

Americas 1 Belgium 2 Canada 5 China 403 Europe 4 France 2 Germany 4 India 18 Japan 6 Slovakia 1 South Korea 1 Switzerland 6 The Netherlands 1 United Kingdom 24 United States 70 Global 548
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
Hattori Corporation
Tel
--
Fax
--
Email
info@hattoricorp.com
Country
Japan
ProdList
1255
Advantage
58
Chemicrea Inc.
Tel
--
Fax
--
Country
Japan
ProdList
93
Advantage
42
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6828
Advantage
80
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6762
Advantage
74
Watanabe Chemical Industries, Ltd.
Tel
--
Fax
--
Country
Japan
ProdList
4813
Advantage
42
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View Lastest Price from (R)-4-Benzyl-2-oxazolidinone manufacturers

Jinan Jianfeng Chemical Co., Ltd
Product
(R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
20ton
Release date
2024-08-14
Hebei Chuanghai Biotechnology Co,.LTD
Product
(R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-21
hebei hongtan Biotechnology Co., Ltd
Product
(R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000
Release date
2024-03-22

102029-44-7, (R)-4-Benzyl-2-oxazolidinoneRelated Search:

(-)-4-Benzyl-2-oxazolidinone,(S)-(-)-4-BENZYL-2-OXAZOLIDINONE,(S)-4-BENZYL-2-OXAZOLIDINONE,4-(S)-Benzyl-2-oxazolidinone,(S)-4-Benzyl-2-oxazolidinone, >99% ee (S)-(+)-4-Phenyl-2-oxazolidinone (N-CHLOROACETYL)-(4S)-BENZYL-2-OXAZOLIDINONE N-PROPIONYL-(4R)-BENZYL-2-OXAZOLIDINONE,N-3-PROPIONYL-(4R)-BENZYL-2-OXAZOLIDINONE (S)-4-(4'-Nitrobenzyl)-1,3-oxazolidine-2-one (R)-(+)-5,5-DIPHENYL-4-BENZYL-2-OXAZOLIDINONE (R)-4-Benzyl-2-oxazolidinone 4-(4-Hydrazinobenzyl)-2-oxazolidinone N-PROPIONYL-(4S)-BENZYL-2-OXAZOLIDINONE,N-3-PROPIONYL-(4S)-BENZYL-2-OXAZOLIDINONE S/R-4-BENZYL-2-OXAZOLIDINONE 2-Oxazolidone (R)-4-(4-AMINOMETHYL-BENZYL)-OXAZOLIDIN-2-ONE (3S,4R)-4-BENZYL-3-(3-METHYLPENTANOYL)-OXAZOLIDIN-2-ONE (N-ACETYL)-(4R)-BENZYL-2-OXAZOLIDINONE Z-D-Phenylalanine N-carboxyanhydride (R)-4-BENZYL-OXAZOLIDINE-2,5-DIONE (R)-4-BENZYL-3-(3-CYCLOPENTYL-PROPIONYL)-OXAZOLIDIN-2-ONE (R)-4-BENZYL-3-(3-CYCLOPROPYL-PROPIONYL)-OXAZOLIDIN-2-ONE

  • 4-benzyl-2-0xazolidinone
  • (R)-4-BENZYL-2-OXAZOLIDINONE HPLC 99+%
  • (R)-4-BENZYL-2-OXAZOLIDINONE 98.0%
  • (4R)-4-(Phenylmethyl)-1,3-oxazolidin-2-one
  • (4R)-4-(Phenylmethyl)-2-oxazolidinone
  • (4R)-Benzyloxazolidin-2-one
  • (4R)-Phenylmethyl-2-oxazolidinone
  • (R)-(+)-4-BENZYL-2-OXAZOLIDINONE FOR SYN
  • (R)-(+)-4-Benzyl-2-oxazolidinone≥ 99.5% (HPLC, Chiral purity)
  • R-BOZ
  • (4R)-4-Benzyl-2-oxo-1,3-oxazolidine, (4R)-4-(Phenylmethyl)-1,3-oxazolidin-2-one
  • (R)-4-Benzyl-2-oxazolidinone 99%
  • (R)-4-Benzyl-2-oxazolidinone, 99%, ee:>99%
  • (R)-4-Benzyl-2-oxazolidinone, >99% ee
  • (R)-4-Benzyl-2-oxazolidinone,99%,>99% ee
  • (R)-4-Benzyl-2-0xazolidinone
  • (R)-(+)-4-Benzyl-2-xazolidineone
  • (R)-4-Benzyl-2-oxazo
  • (R)-4-Benzyl-2-oxazolidinone,99%
  • (4R)-4-Benzyl-2-oxo-1,3-oxazolidine
  • 2-OXAZOLIDINONE, 4-(PHENYLMETHYL)-, (4R)-
  • 2-OXAZOLIDINONE, 4-PHENYL-, (4R)-
  • (4R)-4-BENZYL-1,3-OXAZOLIDIN-2-ONE
  • (4R)-4-BENZYLOXAZOLIDIN-2-ONE
  • (4R)-4-PHENYL-1,3-OXAZOLIDIN-2-ONE
  • (4R)-4-PHENYLOXAZOLIDIN-2-ONE
  • 4-R-BENZYL-2-OXAZOLIDINONE
  • (4R)-PHENYL-2-OXAZOLIDINONE
  • (R)-PH-OXAZOLIDINONE
  • RBOX
  • (R)-4-(PHENYLMETHYL)-2-OXAZOLIDINONE
  • (R)-4-BENZYL-OXAZOLIDIN-2-ONE
  • (R)-(+)-4-BENZYL-2-OXAZOLIDINONE
  • (R)-4-BENZYL-2-OXAZOLIDINONE
  • (R)-(+)-4-BENZYL-2-OXAZOLIDONE
  • <i>(R)</i>-(+)-4-Benzyl-2-oxazolidinone
  • (R)-4-BenzyL
  • (R)-4-Benzyl-2-oxazolidinone &gt
  • -2-oxazoL
  • (R)-4-Benzyl-2-oxazolidinone USP/EP/BP
  • (R)-4-Benzyl-2-oxazolidinone CAS No. 102029-44-7
  • MLS00
  • OJOFMLDBXPDXLQ-SECBINFHSA-N
  • TL806371
  • TB-2044
  • (R)-Solriamfetol Impurity 5
  • 102029-44-7
  • 102021-44-7
  • 99319-52-1
  • 102090-44-7
  • 1022029-44-7
  • 101029-44-7
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Glycidyl Compounds, etc. (Chiral)
  • Chiral Auxiliaries
  • Oxazolidinone Derivatives
  • Asymmetric Synthesis