Thiosildenafil

Product Name: Thiosildenafil
CAS No.: 479073-79-5
Chemical Name: Thiosildenafil
Synonyms: xidi;Sildenafil N;Thiosildenafil;Sildenafil Impurity N;Pinacolborane Impurity 5;Demethyltadalafil Solution, 100ppm;ethyl4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxylate;5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione;5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione;7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-
CBNumber: CB02104269
Molecular Formula: C22H30N6O3S2
Formula Weight: 490.64
MOL File: 479073-79-5.mol

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Thiosildenafil Property

Melting point:: 172-174?C
Boiling point:: 676.1±65.0 °C(Predicted)
Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 5.97±0.42(Predicted)
color: Pale Yellow to Light Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 13939
Product name: Thiosildenafil
Purity: ≥98%
Packaging: 1mg
Price: $43
Updated: 2024/03/01

Cayman Chemical

Product number: 13939
Product name: Thiosildenafil
Purity: ≥98%
Packaging: 5mg
Price: $187
Updated: 2024/03/01

Cayman Chemical

Product number: 13939
Product name: Thiosildenafil
Purity: ≥98%
Packaging: 10mg
Price: $290
Updated: 2024/03/01

Usbiological

Product number: 021790
Product name: Thiosildenafil
Packaging: 10mg
Price: $460
Updated: 2021/12/16

TRC

Product number: T371500
Product name: Thiosildenafil
Packaging: 10mg
Price: $185
Updated: 2021/12/16

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Thiosildenafil Chemical Properties,Usage,Production

Description

Thiosildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .

Chemical Properties

Pale Yellow Solid

Uses

Sildenafil, marketed under the trade name Viagra?, is a potent cGMP-specific phosphodiesterase inhibitor that is highly selective for PDE5. While most notable for its use in the treatment of erectile dysfunction, sildenafil’s vasorelaxant properties have also been used to control vascular tone in pulmonary arterial hypertension and high-altitude pulmonary edema associated with altitude sickness. Thiosildenafil is a derivative of sildenafil that has been found as an adulterant in dietary supplements advertising sexual enhancement for men. The biological characteristics of thiosildenadil have not been reported.[Cayman Chemical]

Uses

An analog of Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.

Uses

An analog of labelled Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.

Thiosildenafil Preparation Products And Raw materials

Raw materials

Preparation Products

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Thiosildenafil Suppliers

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479073-79-5, ThiosildenafilRelated Search:

Sildenafil EP IMpurity D Propoxyphenyl Sildenafil DESMETHYL SILDENAFIL Homo Sildenafil Sildenafil impurity Sildenafil DiMer IMpurity SILDENAFIL N-OXIDE 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,6-dihydro-5-(2-hydroxyphenyl)-1-methyl-3-propyl- 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonamide 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide 5-[2-Ethoxy-5-[(4-Methyl-4-oxido-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-(2-Methylpropyl)-7H-pyrazolo[4,3-d]pyriMidin-7-one Desethyl Sildenafil 1-METHYL-4-NITRO-3-PROPYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 1H-PYRAZOLE-5-CARBOXAMIDE, 4-[[2-ETHOXY-5-[(4-METHYL-1-PIPERAZINYL)SULFONYL]BENZOYL]AMINO]-1-METHYL-3-PROPYL- 4-AMINO-1-METHYL-5-PROPYL-1H-PYRAZOLE-3-CARBOXYLIC ACID AMIDE Pyrazole N-Demethyl Sildenafil Sildenafil 5-[2-ethoxy-5-[4-(trideuteriomethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione

Thiosildenafil

Demethyltadalafil Solution, 100ppm

5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione

Sildenafil N

Sildenafil Impurity N

Sildenafil Impurity 23/Thiosildenafil/5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-thione

7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-

5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione

xidi

Pinacolborane Impurity 5

ethyl4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxylate

479073-79-5

C22H27D3N6O3S2

C22H30N6O3S2

Drug Analogues

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Sulfur & Selenium Compounds

Isotope Labelled Compounds

A