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Thiosildenafil

Product Name
Thiosildenafil
CAS No.
479073-79-5
Chemical Name
Thiosildenafil
Synonyms
xidi;Sildenafil N;Thiosildenafil;Sildenafil Impurity N;Pinacolborane Impurity 5;Thiosildenafil in Methanol;Demethyltadalafil Solution, 100ppm;ethyl4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxylate;5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione;5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione
CBNumber
CB02104269
Molecular Formula
C22H30N6O3S2
Formula Weight
490.64
MOL File
479073-79-5.mol
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Thiosildenafil Property

Melting point:
172-174?C
Boiling point:
676.1±65.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
5.97±0.42(Predicted)
color 
Pale Yellow to Light Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13939
Product name
Thiosildenafil
Purity
≥98%
Packaging
1mg
Price
$43
Updated
2024/03/01
Cayman Chemical
Product number
13939
Product name
Thiosildenafil
Purity
≥98%
Packaging
5mg
Price
$187
Updated
2024/03/01
Cayman Chemical
Product number
13939
Product name
Thiosildenafil
Purity
≥98%
Packaging
10mg
Price
$290
Updated
2024/03/01
Usbiological
Product number
021790
Product name
Thiosildenafil
Packaging
10mg
Price
$460
Updated
2021/12/16
TRC
Product number
T371500
Product name
Thiosildenafil
Packaging
10mg
Price
$185
Updated
2021/12/16
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Thiosildenafil Chemical Properties,Usage,Production

Description

Thiosildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .

Chemical Properties

Pale Yellow Solid

Uses

Sildenafil, marketed under the trade name Viagra?, is a potent cGMP-specific phosphodiesterase inhibitor that is highly selective for PDE5. While most notable for its use in the treatment of erectile dysfunction, sildenafil’s vasorelaxant properties have also been used to control vascular tone in pulmonary arterial hypertension and high-altitude pulmonary edema associated with altitude sickness. Thiosildenafil is a derivative of sildenafil that has been found as an adulterant in dietary supplements advertising sexual enhancement for men. The biological characteristics of thiosildenadil have not been reported.[Cayman Chemical]

Uses

An analog of Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.

Uses

An analog of labelled Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.

Thiosildenafil Preparation Products And Raw materials

Raw materials

Preparation Products

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479073-79-5, ThiosildenafilRelated Search:


  • Thiosildenafil
  • Demethyltadalafil Solution, 100ppm
  • 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione
  • Sildenafil N
  • Sildenafil Impurity N
  • Sildenafil Impurity 23/Thiosildenafil/5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-thione
  • 7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-
  • 5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione
  • xidi
  • Pinacolborane Impurity 5
  • ethyl4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxylate
  • Thiosildenafil in Methanol
  • 479073-79-5
  • 171596-83-6
  • C22H27D3N6O3S2
  • C22H30N6O3S2
  • Drug Analogues
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Isotope Labelled Compounds
  • A
  • 1