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Thiosildenafil

Product Name
Thiosildenafil
CAS No.
479073-79-5
Chemical Name
Thiosildenafil
Synonyms
xidi;Sildenafil N;Thiosildenafil;Sildenafil Impurity N;Pinacolborane Impurity 5;Thiosildenafil in Methanol;Demethyltadalafil Solution, 100ppm;ethyl4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxylate;5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione;5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione
CBNumber
CB02104269
Molecular Formula
C22H30N6O3S2
Formula Weight
490.64
MOL File
479073-79-5.mol
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Thiosildenafil Property

Melting point:
172-174?C
Boiling point:
676.1±65.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
5.97±0.42(Predicted)
color 
Pale Yellow to Light Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13939
Product name
Thiosildenafil
Purity
≥98%
Packaging
1mg
Price
$43
Updated
2024/03/01
Cayman Chemical
Product number
13939
Product name
Thiosildenafil
Purity
≥98%
Packaging
5mg
Price
$187
Updated
2024/03/01
Cayman Chemical
Product number
13939
Product name
Thiosildenafil
Purity
≥98%
Packaging
10mg
Price
$290
Updated
2024/03/01
Usbiological
Product number
021790
Product name
Thiosildenafil
Packaging
10mg
Price
$460
Updated
2021/12/16
TRC
Product number
T371500
Product name
Thiosildenafil
Packaging
10mg
Price
$185
Updated
2021/12/16
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Thiosildenafil Chemical Properties,Usage,Production

Description

Thiosildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .

Chemical Properties

Pale Yellow Solid

Uses

Sildenafil, marketed under the trade name Viagra?, is a potent cGMP-specific phosphodiesterase inhibitor that is highly selective for PDE5. While most notable for its use in the treatment of erectile dysfunction, sildenafil’s vasorelaxant properties have also been used to control vascular tone in pulmonary arterial hypertension and high-altitude pulmonary edema associated with altitude sickness. Thiosildenafil is a derivative of sildenafil that has been found as an adulterant in dietary supplements advertising sexual enhancement for men. The biological characteristics of thiosildenadil have not been reported.[Cayman Chemical]

Uses

An analog of Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.

Uses

An analog of labelled Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.

Thiosildenafil Preparation Products And Raw materials

Raw materials

Preparation Products

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Thiosildenafil Suppliers

JIUWEI
Tel
13323819089
Email
565251196@qq.com
Country
China
ProdList
3
Advantage
58
Henan Wasai Biological Technology Co. LTD
Tel
13526611694
Email
2582571190@qq.com
Country
China
ProdList
69
Advantage
58
Shandong longtai fine chemical co., ltd
Tel
15169750147
Email
1908452573@qq.com
Country
China
ProdList
49
Advantage
58
Shandong Wankang Biotechnology Co. , Ltd.
Tel
131-7317-1119 13173171119
Email
918582503@qq.com
Country
China
ProdList
25
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-83725681-603
Fax
+86 755 28094224
Country
China
ProdList
4496
Advantage
50
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18042
Advantage
56
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
Advantage
55

479073-79-5, ThiosildenafilRelated Search:


  • Thiosildenafil
  • Demethyltadalafil Solution, 100ppm
  • 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione
  • Sildenafil N
  • Sildenafil Impurity N
  • Sildenafil Impurity 23/Thiosildenafil/5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-thione
  • 7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-
  • 5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione
  • xidi
  • Pinacolborane Impurity 5
  • ethyl4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxylate
  • Thiosildenafil in Methanol
  • 479073-79-5
  • 171596-83-6
  • C22H27D3N6O3S2
  • C22H30N6O3S2
  • Drug Analogues
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Isotope Labelled Compounds
  • A
  • 1