N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt

Product Name: N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt
CAS No.: 150374-95-1
Chemical Name: N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt
Synonyms: ONO5046-Na;EI546 sodium;LY544349 sodium;SIVELESTAT SODIUM;Sodium sivelestat;Sivelestat sodium sa;Sivelestat sodium salt;Sivelestat SodiuM anhydrous;N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycinesodiumsalt;sodium,2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate
CBNumber: CB02131171
Molecular Formula: C20H21N2NaO7S
Formula Weight: 456.44
MOL File: 150374-95-1.mol

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N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Property

Melting point:: 104-108 °C(Solv: water (7732-18-5))
storage temp.: Desiccate at RT
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 3535
Product name: Sivelestatsodiumsalt
Purity: ≥98%(HPLC)
Packaging: 10
Price: $125
Updated: 2021/12/16

Tocris

Product number: 3535
Product name: Sivelestatsodiumsalt
Purity: ≥98%(HPLC)
Packaging: 50
Price: $526
Updated: 2021/12/16

Usbiological

Product number: 256675
Product name: Sivelestat sodium salt
Packaging: 10mg
Price: $366
Updated: 2021/12/16

TRC

Product number: S497060
Product name: SivelestatSodium
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-2920
Product name: Sivelestatsodium
Purity: 99.13%
Packaging: 10mg
Price: $84
Updated: 2021/12/16

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N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Chemical Properties,Usage,Production

Uses

Treatment of acute lung injury; acute respiratory distress syndrome (elastase inhibitor).

Uses

Sivelestat Sodium is an inhibitor of neutrophil elastase. Also, it is a promising therapeutic agent for severe acute pneumonitis caused by gefitinib.

Biological Activity

Selective leukocyte elastase inhibitor (IC 50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF- κ B activation and LTB 4 -induced neutrophil transmigration in vitro . Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo .

storage

Desiccate at RT

N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Suppliers

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150374-95-1, N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium saltRelated Search:

ETHANE Chlorodimethylphenylsilane 4-Hydroxy-D-(-)-2-phenylglycine Benzoyl chloride Dimethyl sulfoxide Sulfuryl chloride Dimethyldimethoxysilane Sodium hydroxide Sodium citrate Sivelestat Sodium sulfate BENZOYL ISOCYANATE Dimethyl fumarate Diclofenac sodium Imipenem-Cilastatin sodium hydrate Diethoxydimethylsilane Montelukast sodium Sodium benzoate

n-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(s)-glycine monosodium salt

SIVELESTAT SODIUM

N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycinesodiumsalt

Sivelestat sodium salt

Glycine, N-[2-[[[4-(2,2-diMethyl-1-oxopropoxy)phenyl]sulfonyl]aMino]benzoyl]-, MonosodiuM salt

Sivelestat SodiuM anhydrous

sodium,2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate

sodium 2-[[[2-[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonylamino]phenyl]-oxomethyl]amino]acetate

N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt USP/EP/BP

Sivelestat sodium sa

EI546 sodium

LY544349 sodium

ONO5046-Na

Sodium sivelestat

150374-95-1

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