4-PHENOXYPHENYLACETIC ACID

Product Name: 4-PHENOXYPHENYLACETIC ACID
CAS No.: 6328-74-1
Chemical Name: 4-PHENOXYPHENYLACETIC ACID
Synonyms: NSC 43857;RARECHEM AL BO 1521;4-PHENOXYPHENYLACETIC;4-PHENOXYPHENYLACETIC ACID;p-Phenoxyphenylacetic Acid;4-Phenoxybenzeneacetic Acid;4-Phenoxyphenylethanoic acid;p-Phenyloxyphenylacetic Acid;4-Phenoxyphenylacetic acid 97%;2-(4-PHENOXYPHENYL)ACETIC ACID
CBNumber: CB0217297
Molecular Formula: C14H12O3
Formula Weight: 228.24
MOL File: 6328-74-1.mol

More

Less

4-PHENOXYPHENYLACETIC ACID Property

Melting point:: 72-79 °C
Boiling point:: 382℃
Density: 1.217
refractive index: 1.5800 (estimate)
Flash point:: 146℃
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 4.34±0.10(Predicted)
Appearance: White to off-white Solid
CAS DataBase Reference: 6328-74-1(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xn,N,Xi
Risk Statements: 22-50
Safety Statements: 60-61
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
HazardClass: IRRITANT
HS Code: 29189900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 665053
Product name: 4-Phenoxyphenylacetic acid
Purity: 97%
Packaging: 1g
Price: $44
Updated: 2023/06/20

Sigma-Aldrich

Product number: 665053
Product name: 4-Phenoxyphenylacetic acid
Purity: 97%
Packaging: 5g
Price: $209
Updated: 2023/06/20

TRC

Product number: P318810
Product name: p-PhenyloxyphenylaceticAcid
Packaging: 50mg
Price: $1320
Updated: 2021/12/16

Usbiological

Product number: 019411
Product name: p-Phenyloxyphenylacetic Acid
Packaging: 5mg
Price: $460
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2721-1-45
Product name: 4-Phenoxyphenylacetic acid
Purity: 98%
Packaging: 5G
Price: $324
Updated: 2021/12/16

More

Less

4-PHENOXYPHENYLACETIC ACID Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

p-Phenyloxyphenylacetic Acid is an arylaliphatic acid used in the preperation of protential inhibitors of collagen-induced aggregation of human thrombocytes. p-Phenyloxyphenylacetic Acid is a predicted metabolite of 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline (A621350).

Uses

4-PHENOXYPHENYLACETIC ACID is an arylaliphatic acid used in the preperation of protential inhibitors of collagen-induced aggregation of human thrombocytes. p-Phenyloxyphenylacetic Acid is a predicted metabolite of 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline.

Synthesis

4664-61-3

6328-74-1

General procedure for the synthesis of 4-phenoxyphenylacetic acid from methyl 2-(4-phenoxyphenyl)acetate: 1N aqueous NaOH solution (7.8 mL) was added to a solution of methyl 4-phenoxyphenylacetate (948 mg, 3.9 mmol) in ethanol (20 mL), and the reaction was stirred at room temperature for 5 hours. After completion of the reaction, the reaction solution was concentrated under reduced pressure and acidified by adding 1N aqueous hydrochloric acid (10 mL). The precipitated white solid was collected by filtration and washed with water and ether sequentially to afford 4-phenoxyphenylacetic acid (813 mg, 91% yield) as a white solid. The product was detected by LC-MS showing m/z 229 [M + H]+, and 1H-NMR (300 MHz, CDCl3) data were as follows: δ 6.91-7.01 (m, 4H), 7.10-7.14 (t, J = 6.6 Hz, 1H), 7.25-7.28 (d, J = 8.4 Hz, 2H), 7.35-7.41 (m, 2H) .

References

[1] Patent: EP1849465, 2007, A1. Location in patent: Page/Page column 139
[2] Chemical and pharmaceutical bulletin, 1965, vol. 13, # 11, p. 1341 - 1345
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 13, p. 3695 - 3700

4-PHENOXYPHENYLACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-PHENOXYPHENYLACETIC ACID Suppliers

Canada 1 China 98 Germany 3 India 5 Switzerland 2 United Kingdom 9 United States 24 Global 142

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

More

Less

View Lastest Price from 4-PHENOXYPHENYLACETIC ACID manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-PHENOXYPHENYLACETIC ACID 6328-74-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: 4-PHENOXYPHENYLACETIC ACID 6328-74-1
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2018-08-20

6328-74-1, 4-PHENOXYPHENYLACETIC ACIDRelated Search:

4-PHENOXYPHENYLACETIC ACID 3,3',5-TRIIODOTHYROACETIC ACID Tyromedan 3-PHENOXYPHENYLACETIC ACID 3,5-DIIODOTHYROACETIC ACID HYDROXY-[4-(4-HYDROXY-3,5-DIIODO-PHENOXY)]-3,5-DIIODOPHENYLACETIC ACID METHYL 4-CHLOROPHENYL-[3-(TRIFLUOROMETHYL)PHENOXY]ACETATE ETHYL 4-PHENOXYBENZOYLFORMATE 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID 2-PHENOXYPHENYLACETIC ACID AMINO-(4-PHENOXY-PHENYL)-ACETIC ACID HALOFENATE Bermoprofen (S)-AMINO-(4-PHENOXY-PHENYL)-ACETIC ACID 2-METHYL-2(4-PHENOXYPHENYL)MALONIC ACID (2S)-2-AMINO-2-[2-CHLORO-4-(4-CHLOROPHENOXY)PHENYL]PROPANOIC ACID (2-NAPHTHYLOXY)(PHENYL)ACETIC ACID 2-AMINO-2-(4-PHENOXYPHENYL)ACETIC ACID HYDROCHLORIDE

RARECHEM AL BO 1521

4-PHENOXYPHENYLACETIC ACID

4-PHENOXYPHENYLACETIC

2-(4-PHENOXYPHENYL)ACETIC ACID

2-(4-Phenovbvbvbxyphenyl)acetic acid

4-(Carboxymethyl)diphenyl ether

4-Phenoxyphenylethanoic acid

4-Phenoxybenzeneacetic Acid

NSC 43857

p-Phenyloxyphenylacetic Acid

4-Phenoxyphenylacetic acid 97%

JR-8320, 2-(4-Phenoxyphenyl)acetic acid, 97%

p-Phenoxyphenylacetic Acid

Benzeneacetic acid, 4-phenoxy-

COPPER(II) PHTHALOCYANINE-3 4' 4'' 4'''&

6328-74-1

CARBOXYLIC ACID

Building Blocks

Carboxylic Acids

Carbonyl Compounds

C13 to C42+

Organic Building Blocks

Aromatic Phenylacetic Acids and Derivatives

Phenylacetic acid

Aromatics

Inhibitors

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals