ChemicalBook > CAS DataBase List > Indole-4-carboxaldehyde

Indole-4-carboxaldehyde

Product Name
Indole-4-carboxaldehyde
CAS No.
1074-86-8
Chemical Name
Indole-4-carboxaldehyde
Synonyms
4-INDOLECARBALDEHYDE;1H-INDOLE-4-CARBALDEHYDE;4-FLUOROINDOLE;1H-INDOLE-4-CARBOXALDEHYDE;NSC 337264;e-4-carboxaL;4-FORMYLINDOLE;INDOLE-4-ALDEHYDE;4-Formyl-1H-indole;RARECHEM AH BS 0110
CBNumber
CB0217303
Molecular Formula
C9H7NO
Formula Weight
145.16
MOL File
1074-86-8.mol
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Indole-4-carboxaldehyde Property

Melting point:
139-143 °C(lit.)
Boiling point:
339.1±15.0 °C(Predicted)
Density 
1.278±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMF: 10 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka
15.84±0.30(Predicted)
form 
powder to crystal
color 
Light yellow to Brown
Water Solubility 
Soluble in ethanol and acetone. Insoluble in water.
Sensitive 
Air Sensitive
CAS DataBase Reference
1074-86-8(CAS DataBase Reference)
NIST Chemistry Reference
1H-indole-4-carboxaldehyde(1074-86-8)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36-43
Safety Statements 
26-36/37
WGK Germany 
3
Hazard Note 
Irritant/Keep Cold
HazardClass 
IRRITANT
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
632422
Product name
Indole-4-carboxaldehyde
Purity
97%
Packaging
1g
Price
$129
Updated
2023/06/20
Sigma-Aldrich
Product number
632422
Product name
Indole-4-carboxaldehyde
Purity
97%
Packaging
5g
Price
$628
Updated
2023/06/20
TCI Chemical
Product number
I0712
Product name
Indole-4-carboxaldehyde
Purity
>98.0%(GC)
Packaging
1g
Price
$160
Updated
2024/03/01
TCI Chemical
Product number
I0712
Product name
Indole-4-carboxaldehyde
Purity
>98.0%(GC)
Packaging
5g
Price
$400
Updated
2024/03/01
Alfa Aesar
Product number
H28019
Product name
Indole-4-carboxaldehyde, 97%
Packaging
5g
Price
$713
Updated
2021/12/16
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Indole-4-carboxaldehyde Chemical Properties,Usage,Production

Chemical Properties

White to dark brown solid

Uses

4-Indolecarbaldehyde is a synthetic intermediate used for pharmaceutical synthesis. Also used as reactant in Biginelli reaction, synthesis of aurora kinase A inhibitors, preparation of antitumor agents, intermolecular Friedel-Crafts acylation, preparation of inhibitors of cell division in E. coli and synthesis of Hantzsch pyridine-containing Schiff bases.

Uses

Indole-4-carboxaldehyde is usually used as reactant in Biginelli reaction,preparation of antitumor agents,intramolecular Friedel-Crafts acylation,preparation of inhibitors of cell division in E. Coli,synthesis of Hantzsch pyridine-containing Schiff bases.

Definition

ChEBI: Indole-4-carbaldehyde is a heteroarenecarbaldehyde that is indole in which the hydrogen at position 4 has been replaced by a formyl group. It has a role as an algal metabolite. It is a member of indoles and a heteroarenecarbaldehyde.

Synthesis Reference(s)

The Journal of Organic Chemistry, 46, p. 1752, 1981 DOI: 10.1021/jo00321a053
Tetrahedron, 39, p. 3695, 1983 DOI: 10.1016/S0040-4020(01)88608-7

General Description

Indole-4-carboxaldehyde participates in the synthesis of arcyriacyanin A. Synthesis of 4-indole-4-carboxaldehyde has been reported. Intramolecular Friedel-Crafts (FC) acylation of indole-4-carboxaldehyde has been reported.

Indole-4-carboxaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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Indole-4-carboxaldehyde Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
ProdList
94838
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
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China
ProdList
40241
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INTATRADE GmbH
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+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
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66
Bridge Organics
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+1269-649-4200
Fax
+1269-649-0611
Email
ab@bridgeorganics.com
Country
United States
ProdList
163
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
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81
Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
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sales8178@energy-chemical.com
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China
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
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86-027-87531808
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sales@chemwish.com
Country
China
ProdList
35906
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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sales@capotchem.com
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China
ProdList
18217
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66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
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View Lastest Price from Indole-4-carboxaldehyde manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Indole-4-carboxaldehyde 1074-86-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
Indole-4-carboxaldehyde 1074-86-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
Indole-4-carboxaldehyde 1074-86-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-30

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