Indole-7-carboxaldehyde
- Product Name
- Indole-7-carboxaldehyde
- CAS No.
- 1074-88-0
- Chemical Name
- Indole-7-carboxaldehyde
- Synonyms
- 1H-INDOLE-5-CARBALDEHYDE;1H-INDOLE-7-CARBALDEHYDE;e-7-carboxaL;7-FORMYLINDOLE;7-Indolealdehyde;INDOLE-7-ALDEHYDE;7-Formyl-1H-indole;RARECHEM AH BS 0111;INDOLE-7-CARBALDEHYDE;7-Indolecarboxaldehyde
- CBNumber
- CB8731641
- Molecular Formula
- C9H7NO
- Formula Weight
- 145.16
- MOL File
- 1074-88-0.mol
Indole-7-carboxaldehyde Property
- Melting point:
- 87-91 °C (lit.)
- Boiling point:
- 339.1±15.0 °C(Predicted)
- Density
- 1.278±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform, Dichloromethane
- form
- Solid
- pka
- 15.50±0.30(Predicted)
- color
- Yellow Crystalline
- Water Solubility
- insoluble
- Sensitive
- Air Sensitive
- BRN
- 1524960
- InChI
- InChI=1S/C9H7NO/c11-6-8-3-1-2-7-4-5-10-9(7)8/h1-6,10H
- InChIKey
- XQVZDADGTFJAFM-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC=C2C=O)C=C1
- CAS DataBase Reference
- 1074-88-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 632414
- Product name
- Indole-7-carboxaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $112
- Updated
- 2025/07/31
- Product number
- 632414
- Product name
- Indole-7-carboxaldehyde
- Purity
- 97%
- Packaging
- 5g
- Price
- $303
- Updated
- 2023/06/20
- Product number
- I0701
- Product name
- 1H-Indole-7-carbaldehyde
- Purity
- min. 98.0 %
- Packaging
- 1G
- Price
- $57
- Updated
- 2025/07/31
- Product number
- I0701
- Product name
- 1H-Indole-7-carbaldehyde
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $172
- Updated
- 2025/07/31
- Product number
- I615030
- Product name
- Indole-7-carboxaldehyde
- Packaging
- 1g
- Price
- $175
- Updated
- 2021/12/16
Indole-7-carboxaldehyde Chemical Properties,Usage,Production
Chemical Properties
Yellow Crystalline Solid
Uses
Indole-7-carboxaldehyde (cas# 1074-88-0) is a compound useful in organic synthesis.
Uses
Indole-7-carboxaldehyde is used in an efficient synthesis of fused pyrroloquinolinedicarboxylates from acetylenedicarboxylates and triphenylphosphine. 1.reactant for preparation of antiandrogens. 2.reactant for preparation of antiplatelet agent. 3.reactant for preparation of liver
Definition
ChEBI: Indole-7-carboxaldehyde is a member of indoles.
Synthesis Reference(s)
Synthetic Communications, 36, p. 1051, 2006 DOI: 10.1080/00397910500503470
Synthesis
1074-87-9
1074-88-0
General procedure for the synthesis of indole-7-carboxaldehyde from (1H-indol-7-yl)methanol: (1H-indol-7-yl)methanol (8.0 g, 54.3 mmol) was dissolved in 400 mL of dichloromethane, and activated manganese(IV) oxide (85%, 41.0 g, 0.40 mol) was added. The reaction mixture was stirred at room temperature for 72 hours. Upon completion of the reaction, 200 mL of dichloromethane and 400 mL of methanol were added to the mixture, followed by filtration through a silica gel pad to remove solid impurities. The filtrate was concentrated to give the crude product, which was further purified by silica gel column chromatography to afford the target product 1H-indole-7-carboxaldehyde (I-1) (6.55 g, 83% yield). The structure of the product was confirmed by 1H-NMR (CDCl3).
References
[1] Synthetic Communications, 2006, vol. 36, # 8, p. 1051 - 1056
[2] Patent: US2006/79520, 2006, A1. Location in patent: Page/Page column 43
[3] Patent: WO2006/44415, 2006, A2. Location in patent: Page/Page column 78; 106-107
[4] Journal of the American Chemical Society, 2006, vol. 128, # 12, p. 4023 - 4034
[5] Chemical and Pharmaceutical Bulletin, 1986, vol. 34, # 10, p. 4116 - 4125
Indole-7-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Indole-7-carboxaldehyde manufacturers
- Product
- Indole-7-carboxaldehyde 1074-88-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-08
- Product
- 7-Formylindole Indole-7-carboxaldehyde in stock Factory 1074-88-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- TOP 3 Factory in China
- Supply Ability
- Top 3 largest production capacity Factory
- Release date
- 2019-04-03
- Product
- Indole-7-carboxaldehyde 1074-88-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-25