1H-INDAZOLE-5-CARBONITRILE

Product Name: 1H-INDAZOLE-5-CARBONITRILE
CAS No.: 74626-47-4
Chemical Name: 1H-INDAZOLE-5-CARBONITRILE
Synonyms: 5-Cyanoindazole;5-Cyano-1H-indazole;Indazole-5-carbonitrile;1H-INDAZOLE-5-CARBONITRILE;1H-Indazole-5-carbonitrile(9CI);1H-Indazole-5-carbonitrile ,97%
CBNumber: CB1150283
Molecular Formula: C8H5N3
Formula Weight: 143.15
MOL File: 74626-47-4.mol

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1H-INDAZOLE-5-CARBONITRILE Property

Boiling point:: 370.3±15.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
form: Solid
pka: 12.19±0.40(Predicted)
Appearance: Pink to red Solid
CAS DataBase Reference: 74626-47-4

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: I509063
Product name: 1H-Indazole-5-carbonitrile
Packaging: 100mg
Price: $60
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H37-1-N3
Product name: 1H-Indazole-5-carbonitrile
Packaging: 250mg
Price: $29
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H37-1-N3
Product name: 1H-Indazole-5-carbonitrile
Packaging: 1g
Price: $93
Updated: 2021/12/16

Matrix Scientific

Product number: 057941
Product name: 1H-Indazole-5-carbonitrile
Purity: 98%
Packaging: 1g
Price: $220
Updated: 2021/12/16

Matrix Scientific

Product number: 057941
Product name: 1H-Indazole-5-carbonitrile
Purity: 98%
Packaging: 5g
Price: $430
Updated: 2021/12/16

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1H-INDAZOLE-5-CARBONITRILE Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

146137-79-3

74626-47-4

General procedure for the synthesis of indazole-5-carbonitrile from 4-fluoro-3-formylbenzonitrile: 4-fluoro-3-formylbenzonitrile (25 g, 16.78 mmol) was dissolved in 100 mL of 85% hydrazine hydrate. The reaction mixture was stirred at room temperature for 24 hours. After completion of the reaction, the product was purified by column chromatography to afford 1H-indazole-5-carbonitrile (2.1 g, 87% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6) and mass spectrometry (ESI): 1H NMR δ 13.60 (s, 1H), 8.42 (s, 1H), 8.27 (s, 1H), 7.73 (d, J = 8.6 Hz, 1H), 7.67 (d, J = 8.6 Hz, 1H); MS m/z (ESI): 144 [M + H]+.

References

[1] Patent: EP3205650, 2017, A1. Location in patent: Paragraph 0106; 0345
[2] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 15, p. 4191 - 4195
[3] Synthetic Communications, 1997, vol. 27, # 7, p. 1199 - 1207
[4] Patent: US6376499, 2002, B1
[5] Patent: US6610692, 2003, B1

1H-INDAZOLE-5-CARBONITRILE Preparation Products And Raw materials

Raw materials

Copper(I) Cyanide Palladium Sodium nitrite 2-Methyl-4-nitroaniline Hydrochloric acid Acetic acid POTASSIUM CYANIDE

Preparation Products

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1H-INDAZOLE-5-CARBONITRILE Suppliers

China 126 Europe 1 France 1 Germany 2 India 1 United Kingdom 1 United States 22 Global 154

Suzhou Yimaike Pharmaceutical Co., Ltd.

Tel: 18701861866
Email: suzhouyimaike@163.com
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J & K SCIENTIFIC LTD.

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ChemFuture PharmaTech (Jiangsu) Ltd

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Jia Xing Isenchem Co.,Ltd

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Email: isenchem@163.com
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Shangchem Co., Ltd.

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky（shanghai）International Co.,Ltd.

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China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
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Country: China
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View Lastest Price from 1H-INDAZOLE-5-CARBONITRILE manufacturers

Career Henan Chemical Co

Product: 1H-INDAZOLE-5-CARBONITRILE 74626-47-4
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-10

Career Henan Chemical Co

Product: 4-keto-L-proline hydrobromide 75776-67-9
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-10

74626-47-4, 1H-INDAZOLE-5-CARBONITRILERelated Search:

(1H-INDAZOL-3-YL)-ACETIC ACID 1H-INDAZOLE-5-BORONIC ACID 1H-Indazole-3-carboxamide(6CI,7CI,9CI) Indazole-4-boronic acid, HCl 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER 1H-INDAZOLE-4-CARBOXYLIC ACID 5-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER Indazole-4-boronic acid, hydrochloride 7-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE 5-Carboxyindazole hydrochloride 1H-INDAZOL-7-YL BORONIC ACID Indazole 4-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER 6-INDAZOLYBORONIC ACID Ethyl indole-2-carboxylate Indole-7-carboxaldehyde Indazole-3-carboxylic acid

1H-Indazole-5-carbonitrile ,97%

5-Cyanoindazole

Indazole-5-carbonitrile

5-Cyano-1H-indazole

1H-INDAZOLE-5-CARBONITRILE

1H-Indazole-5-carbonitrile(9CI)

74626-47-4

pharmacetical

Building Blocks

Indazole

NITRILE