ChemicalBook > CAS DataBase List > 7-Bromoquinolin-8-ol

7-Bromoquinolin-8-ol

Product Name
7-Bromoquinolin-8-ol
CAS No.
13019-32-4
Chemical Name
7-Bromoquinolin-8-ol
Synonyms
7-bromo-8-Quinolinol;7-Bromoquinolin-8-ol;8-Quinolinol, 7-bromo-;7-BroMo-8-hydroxyquinoline;7-bromo-8-hydroxyquinolinol;7-BroMo-8-hydroxyquinoline 97%
CBNumber
CB02235895
Molecular Formula
C9H6BrNO
Formula Weight
224.05
MOL File
13019-32-4.mol
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7-Bromoquinolin-8-ol Property

Melting point:
138-143 °C
Boiling point:
327.9±22.0 °C(Predicted)
Density 
1.705±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
2.43±0.50(Predicted)
form 
powder
InChI
InChI=1S/C9H6BrNO/c10-7-4-3-6-2-1-5-11-8(6)9(7)12/h1-5,12H
InChIKey
ICKPMTNGWVNOGC-UHFFFAOYSA-N
SMILES
N1C2C(=CC=C(Br)C=2O)C=CC=1
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Safety

Hazard Codes 
Xn
Risk Statements 
22-41
Safety Statements 
26
WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
722049
Product name
7-Bromo-8-hydroxyquinoline
Purity
97%
Packaging
5g
Price
$38.1
Updated
2025/07/31
TRC
Product number
B997303
Product name
7-Bromoquinolin-8-ol
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
0939AQ
Product name
7-Bromo-8-hydroxyquinoline
Packaging
5g
Price
$207
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0067064
Product name
7-BROMO-8-HYDROXYQUINOLINE
Purity
95.00%
Packaging
1G
Price
$288.75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0067064
Product name
7-BROMO-8-HYDROXYQUINOLINE
Purity
95.00%
Packaging
5G
Price
$897.44
Updated
2021/12/16
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7-Bromoquinolin-8-ol Chemical Properties,Usage,Production

Synthesis

148-24-3

521-74-4

13019-32-4

The general procedure for the synthesis of 5,7-dibromo-8-hydroxyquinoline and 7-bromo-8-hydroxyquinoline from 8-hydroxyquinoline was as follows: bromination was carried out according to the method described in the literature [19]. This was done as follows: 8-hydroxyquinoline (2 mmol, 1 eq.) was dissolved in distilled CHCl3 (15 mL) at room temperature and protected from light, followed by the slow addition of different equivalents of molecular bromine (dissolved in CHCl3) over a period of 10 min. The reaction mixture was stirred continuously for 2 days, during which the progress of the reaction was monitored by TLC. Upon completion of the reaction, the organic layer was washed with 5% NaHCO3 solution (3 x 20 mL), dried over anhydrous Na2SO4 and concentrated under reduced pressure. Finally, the target product was separated by alumina column chromatography with ethyl acetate/hexane (1:5, 150 mL) as eluent.

References

[1] Letters in Drug Design and Discovery, 2017, vol. 14, # 12, p. 1415 - 1424

7-Bromoquinolin-8-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Bromoquinolin-8-ol Suppliers

Shanghai Taifu Pharmaceutical Technology Co., LTD
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