ChemicalBook > CAS DataBase List > 7-Bromoquinolin-8-ol
7-Bromoquinolin-8-ol
- Product Name
- 7-Bromoquinolin-8-ol
- CAS No.
- 13019-32-4
- Chemical Name
- 7-Bromoquinolin-8-ol
- Synonyms
- 7-bromo-8-Quinolinol;7-Bromoquinolin-8-ol;8-Quinolinol, 7-bromo-;7-BroMo-8-hydroxyquinoline;7-bromo-8-hydroxyquinolinol;7-BroMo-8-hydroxyquinoline 97%
- CBNumber
- CB02235895
- Molecular Formula
- C9H6BrNO
- Formula Weight
- 224.05
- MOL File
- 13019-32-4.mol
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7-Bromoquinolin-8-ol Property
- Melting point:
- 138-143 °C
- Boiling point:
- 327.9±22.0 °C(Predicted)
- Density
- 1.705±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 2.43±0.50(Predicted)
- form
- powder
- InChI
- InChI=1S/C9H6BrNO/c10-7-4-3-6-2-1-5-11-8(6)9(7)12/h1-5,12H
- InChIKey
- ICKPMTNGWVNOGC-UHFFFAOYSA-N
- SMILES
- N1C2C(=CC=C(Br)C=2O)C=CC=1
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 722049
- Product name
- 7-Bromo-8-hydroxyquinoline
- Purity
- 97%
- Packaging
- 5g
- Price
- $38.1
- Updated
- 2025/07/31
TRC
- Product number
- B997303
- Product name
- 7-Bromoquinolin-8-ol
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
AK Scientific
- Product number
- 0939AQ
- Product name
- 7-Bromo-8-hydroxyquinoline
- Packaging
- 5g
- Price
- $207
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- HCH0067064
- Product name
- 7-BROMO-8-HYDROXYQUINOLINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $288.75
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- HCH0067064
- Product name
- 7-BROMO-8-HYDROXYQUINOLINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $897.44
- Updated
- 2021/12/16
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7-Bromoquinolin-8-ol Chemical Properties,Usage,Production
Synthesis
148-24-3
521-74-4
13019-32-4
The general procedure for the synthesis of 5,7-dibromo-8-hydroxyquinoline and 7-bromo-8-hydroxyquinoline from 8-hydroxyquinoline was as follows: bromination was carried out according to the method described in the literature [19]. This was done as follows: 8-hydroxyquinoline (2 mmol, 1 eq.) was dissolved in distilled CHCl3 (15 mL) at room temperature and protected from light, followed by the slow addition of different equivalents of molecular bromine (dissolved in CHCl3) over a period of 10 min. The reaction mixture was stirred continuously for 2 days, during which the progress of the reaction was monitored by TLC. Upon completion of the reaction, the organic layer was washed with 5% NaHCO3 solution (3 x 20 mL), dried over anhydrous Na2SO4 and concentrated under reduced pressure. Finally, the target product was separated by alumina column chromatography with ethyl acetate/hexane (1:5, 150 mL) as eluent.
References
[1] Letters in Drug Design and Discovery, 2017, vol. 14, # 12, p. 1415 - 1424
7-Bromoquinolin-8-ol Preparation Products And Raw materials
Raw materials
Preparation Products
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