ChemicalBook > CAS DataBase List > 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid

4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid

Product Name
4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid
CAS No.
5623-18-7
Chemical Name
4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid
Synonyms
Metfol-B;NSC 408937;Methotrexate-EP-Imp-D;N10-Methyl Pteroic Acid;Methotrexate EP Impurity D;Methotrexate Impurity 4(EP-D);Methotrexate Impurity 4（Methotrexate EP Impurity D）;Methotrexate EP Impurity D（Amethopterin EP Impurity D）;4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]methylamino}benzoic acid;p-[(2-Amino-4-hydroxy-6-pteridinyl)methyl(methyl)amino]benzoic acid
CBNumber
CB02262484
Molecular Formula
C15H14N6O3
Formula Weight
326.31
MOL File
5623-18-7.mol
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4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid Property

Melting point:
>245°C (dec.)
Boiling point:
583.7±60.0 °C(Predicted)
Density 
1.58±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Aqueous Base (Slightly), DMSO (Very Slightly, Heated), Methanol (Very Slightly)
pka
4.74±0.10(Predicted)
color 
Orange to Red
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M1000008
Product name
Methotrexate impurity D
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
m1000008
Price
$220
Updated
2024/03/01
TRC
Product number
M326265
Product name
N10-MethylPteroicAcid
Packaging
250mg
Price
$810
Updated
2021/12/16
TRC
Product number
M326265
Product name
N10-MethylPteroicAcid
Packaging
500mg
Price
$1455
Updated
2021/12/16
TRC
Product number
M326265
Product name
N10-MethylPteroicAcid
Packaging
25mg
Price
$105
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
60247
Product name
N10-MethylPteroicAcid
Packaging
500mg
Price
$2200
Updated
2021/12/16
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4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid Chemical Properties,Usage,Production

Chemical Properties

Dark Orange Solid

Uses

N10-Methyl Pteroic Acid (Methotrexate EP Impurity D) is a Methotrexate (M260675) impurity D.

Uses

Methotrexate (M260675) impurity D.

4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid Suppliers

Canada 1 China 54 India 3 United States 6 Global 64
Toronto Research Chemicals
Tel
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Fax
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Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
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5623-18-7, 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acidRelated Search:

7-HYDROXY METHOTREXATE METHOTREXATE DIMETHYL ESTER Methotrexate Related Compound E (50 mg) (4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoic acid, hemihydrochloride) Methotrexate γ-Methyl Ester Methotrexate α-Methyl Ester METHOTREXATE-D3 2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE 4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID Methotrexate L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- methotrexate-gamma-dimethylamide N-(4-(METHYLAMINO)BENZOYL)-L-GLUTAMIC ACID 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide Aminopterin Methotrexate EP Impurity G D(-)-AMETHOPTERIN L-Glutamic acid der. Folic Acid Related Compound A/Calcium Formyltetrahydrofolate

  • p-[(2-Amino-4-hydroxy-6-pteridinyl)methyl(methyl)amino]benzoic acid
  • N10-Methyl Pteroic Acid
  • 4-[[(2-AMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]MethylaMino]benzoic Acid
  • Metfol-B
  • NSC 408937
  • 4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]methylamino}benzoic acid
  • Methotrexate EP Impurity D
  • Methotrexate Impurity 4(EP-D)
  • Methotrexate EP Impurity D/N10-Methylpteroic acid/4-(((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl)(methyl)amino)benzoic acid
  • Methotrexate EP Impurity D（Amethopterin EP Impurity D）
  • Methotrexate-EP-Imp-D
  • 4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl](methyl)amino}benzoic acid
  • Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]-
  • Methotrexate Impurity 4（Methotrexate EP Impurity D）
  • 4-(((2-Amino-4-oxo-4,8-dihydropteridin-6-yl)methyl)(methyl)amino)benzoic acid (Methotrexate Impurity)
  • 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid
  • 5623-18-7
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals