Rutaecarpine

Product Name: Rutaecarpine
CAS No.: 84-26-4
Chemical Name: Rutaecarpine
Synonyms: RUTECARPINE;Rutacarpine;RHETINE;Rutaecarpine;Rutaccarpine;RUTECARPINE 95+;Rutaecarpine >Rutaecarpine std.;Rutecarpine (8CI);Rutaecarpine 84-26-4
CBNumber: CB0226965
Molecular Formula: C18H13N3O
Formula Weight: 287.32
MOL File: 84-26-4.mol

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Rutaecarpine Property

Melting point:: 259.5-260°
Boiling point:: 429.62°C (rough estimate)
Density: 1.2030 (rough estimate)
refractive index: 1.5855 (estimate)
storage temp.: Sealed in dry,2-8°C
solubility: DMSO: 18 mg/mL clear yellow solution, soluble
form: solid
pka: 15.79±0.20(Predicted)
color: white
Merck: 14,8298
InChIKey: ACVGWSKVRYFWRP-UHFFFAOYSA-N
CAS DataBase Reference: 84-26-4(CAS DataBase Reference)

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Safety

Hazard Codes: T
Risk Statements: 25-36/37/38
Safety Statements: 45-36-26
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: NM3454000
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R3277
Product name: Rutaecarpine
Purity: >98% (HPLC)
Packaging: 5mg
Price: $162
Updated: 2024/03/01

Sigma-Aldrich

Product number: R3277
Product name: Rutaecarpine
Purity: >98% (HPLC)
Packaging: 25mg
Price: $253.6
Updated: 2024/03/01

TCI Chemical

Product number: R0102
Product name: Rutaecarpine
Purity: >98.0%(HPLC)(N)
Packaging: 200mg
Price: $220
Updated: 2024/03/01

Cayman Chemical

Product number: 22897
Product name: Rutaecarpine
Purity: ≥98%
Packaging: 5mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 22897
Product name: Rutaecarpine
Purity: ≥98%
Packaging: 10mg
Price: $82
Updated: 2024/03/01

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Rutaecarpine Chemical Properties,Usage,Production

Description

This alkaloid occurs with Evodiamine (q.v.) in the Chinese drug 'Wou-chou-yu' which is the dried fruit of Evodia rutaecarpa Benth. It crystallizes from boiling EtOH as colourless, or pale yellow, needles and is optically inactive. The acetyl derivative has m.p. 184-6°C and the benzoyl compound, m.p. 194°C. The alkaloid gives a yellow colour with concentrated H2S04 and is decomposed by KOH in boiling amyl alcohol yielding anthranilic acid and 3-{3-aminoethylindole- 2-O!carboxylic acid, CllH120 2N2, silky crystals, m.p. 257°C.
Pharmacologically, the alkaloid causes increased arterial pressure on injection.

Chemical Properties

Solid

Uses

Rutaecarpine is an indole alkaloid contained in the fruit of Evodiae fruits. It been shown to ameliorate bodyweight gain through orexigenic neuropeptides NPY and AgRP. It also playes a role in the treatment of high blood pressure

Definition

ChEBI: Rutecarpine is a member of beta-carbolines.

References

Asahina, Kashiwagi., J. Pharm. Chim., 14,54 (1916)
Asahina, Mayeda.,J. Pharm. Soc., Japan, No. 416 (1916)
Asahina, Fujita., ibid, 863 (1921)
Kermack, Perkin, Robinson.,J. Chem. Soc., 119,1615 (1921)
Asahina, Manske, Robinson., ibid, 1708 (1927)
Asahina, Irie, Ohta., J. Pharm. Soc., Japan, 48, 51 (1928)
Ohta., ibid, 60, 109 (1940)
Schopf, Steuer., Annalen, 558, 124 (1947)
Biosynthesis:
Yamazaki, Ikuta., Tetrahedron Lett., 3221 (1966)
Yamazakietal., ibid, 3317 (1967)
Pharmacology:
Raymond-Hamet., Cornpt. rend., 220, 749 (1945)

Rutaecarpine Preparation Products And Raw materials

Raw materials

Preparation Products

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Rutaecarpine Suppliers

China 274 Germany 1 India 2 Japan 1 Switzerland 1 United Kingdom 6 United States 30 Global 315

Shanxi Yuning Biotechnology Co., Ltd.

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J & K SCIENTIFIC LTD.

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Chembest Research Laboratories Limited

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Country: China
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
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Email: Sales-CN@TCIchemicals.com
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Adamas Reagent, Ltd.

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Sinopharm Chemical Reagent Co,Ltd.

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Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
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Country: China
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View Lastest Price from Rutaecarpine manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Rutaecarpine 84-26-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-24

Wuhan Senwayer Century Chemical Co.,Ltd

Product: Rutaecarpine 84-26-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2022-11-02

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Rutaecarpine 84-26-4
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min HPLC
Supply Ability: 100kg
Release date: 2021-09-15

84-26-4, RutaecarpineRelated Search:

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:3,4]pyrido[2,1-b]quinazolin-5(7H)-one

Indolo(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13-dihydro- (9CI)

Rutacarpine

Rutecarpine (8CI)

7,8-dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one

RHETINE

RUTECARPINE

8,13-DIHYDRO-INDOLO[2'3':3,4]PYRIDO[2,1-B]QUINAZOLIN-5(7H)-ONE

RUTECARPINE 95+

Rutaecarpine std.

Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one,8,13-dihydro-

Rutecarpine, 8,13-Dihydroindolo[2μ,3μ:3,4]pyrido[2,1-b]quinazolin-5(7H)-one

5,7,8,13-Tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazoline-5-one

Rutaecarpine (Rutecarpine)

Rutaecarpine

Rutaecarpine (synthetic)

Rutaecarpine, froM TetradiuM ruticarpuM

Rutaecarpine, 98%, from Evodia rutaecarpa (Juss.) Benth.

Rutaecarpine 84-26-4

Rutaecarpine &gt

Rutaecarpine USP/EP/BP

Rutaccarpine

Rutaecarpine 98%min

7,8-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one

84-26-4

84-16-4

Cell Signaling and Neuroscience

Ion Channels

Monovalent Ion Channels

Potassium Channel Modulators

Voltage-gated Ion Channels

BioChemical

Cell Biology

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Indoles and derivatives

Inhibitors