ChemicalBook > CAS DataBase List > CADP-RIBOSE

CADP-RIBOSE

Product Name
CADP-RIBOSE
CAS No.
119340-53-3
Chemical Name
CADP-RIBOSE
Synonyms
CADPR;C13050;CYCLIC ADPR;CADP-RIBOSE;CYCLIC ADP-RIBOSE;CADPR SODIUM SALT;cADP-Ribose (cADPR);ADP-CYCLO-[N1:1'']-RIBOSE;cADP-ribose ammonium salt;CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE
CBNumber
CB0236872
Molecular Formula
C15H21N5O13P2
Formula Weight
541.3
MOL File
119340-53-3.mol
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CADP-RIBOSE Property

Boiling point:
934.8±75.0 °C(Predicted)
Density 
2.57±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Very Slightly), Water (Slightly)
form 
lyophilized powder
pka
0.97±0.70(Predicted)
color 
White to off-white
biological source
(Ovotestis from sea hare)
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C7344
Product name
Cyclic adenosine diphosphate-ribose
Purity
≥90% (HPLC), lyophilized powder
Packaging
0.5mg
Price
$332
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
CRB0002983
Product name
CADP-RIBOSE
Purity
95.00%
Packaging
100G
Price
$197.4
Updated
2021/12/16
Biosynth Carbosynth
Product number
NC11582
Product name
Cyclic adenosine 5'-diphosphate ribose ammonium salt
Packaging
250ug
Price
$225
Updated
2021/12/16
Biosynth Carbosynth
Product number
NC11582
Product name
Cyclic adenosine 5'-diphosphate ribose ammonium salt
Packaging
500ug
Price
$350
Updated
2021/12/16
Biosynth Carbosynth
Product number
NC11582
Product name
Cyclic adenosine 5'-diphosphate ribose ammonium salt
Packaging
1mg
Price
$675
Updated
2021/12/16
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CADP-RIBOSE Chemical Properties,Usage,Production

Uses

Cyclic adenosine diphosphate-ribose (cADPR) is an intracellular second messenger that mobilizes intracellular Ca2+ release from the sarcoplasmic reticulum through ryanodine receptors. CADPR is also a second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants.

Definition

ChEBI: A cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors.

Biochem/physiol Actions

Mobilizes intracellular Ca2+; regulates Ca2+-induced Ca2+?release specifically blocked by ryanodine; second messenger for glucose-induced insulin release from the endocrine pancreas and for abscisic acid-induced calcium release in plants.

in vivo

cADPR (100 μM; push-pull type of brain microperfusion) elevats OT concentrations in ordinate or subordinate mice[5].

CADP-RIBOSE Preparation Products And Raw materials

Raw materials

Preparation Products

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CADP-RIBOSE Suppliers

China 29 Germany 2 Switzerland 1 United Kingdom 2 United States 7 Global 41
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119340-53-3, CADP-RIBOSERelated Search:

NAD+ DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS* 3-DEAZA-CADP-RIBOSE 8-AMINO-CADP-RIBOSE BR-CADP-RIBOSE,8-BROMO-CADP-RIBOSE ANTI-CADP-RIBOSE NPE-CAGED CADP-RIBOSE CADP-RIBOSE 6-(BETA-HYDROXYETHYLAMINO)-PURINE

  • cyclicadenosinediphosphateribose(cadpr),sodiumsalt
  • CYCLIC ADP RIBOSE POTENT INTRACELLULAR
  • ADP-cyclo[N1:1μμ]-ribose, cADP-ribose, cADPR, Cyclic ADPR
  • C13050
  • cADP-Ribose (cADPR)
  • N-ALPHA-D-RIOFURANOSYL-P',5''-ESTER ADENOSINE 5'-(TRIHYDROGEN DIPHOSPHATE)
  • CYCLIC ADENOSINE 5'-DIPHOSPHATE RIBOSE
  • CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE
  • CYCLIC ADENOSINE DIPHOSPHATE RIBOSE SODIUM SALT
  • CYCLIC ADPR
  • CYCLIC ADP-RIBOSE
  • CADPR
  • CADP-RIBOSE
  • ADP-CYCLO-[N1:1'']-RIBOSE
  • Adenosine5'-(trihydrogen diphosphate), 1-b-D-ribofuranosyl-, intramol. P',5''-ester
  • Cyclic adenosine 5'-diphosphate ribose ammonium salt
  • CADPR SODIUM SALT
  • Adenosine 5'-(trihydrogen diphosphate), 1-β-D-ribofuranosyl-, intramol. P',5''-ester
  • cADP-Ribose (cADPR) DISCONTINUED. Please see A291808.
  • Cyclic ADP?ribose,Cyclic ADP ?ribose
  • cADP-ribose ammonium salt
  • 119340-53-3
  • 119340-53-5
  • C15H21N5O13P2
  • C15H21N5O13P2NH3
  • Intracellular Calcium Signaling
  • Intracellular Calcium Regulators
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical