KM 11060

Product Name: KM 11060
CAS No.: 774549-97-2
Chemical Name: KM 11060
Synonyms: KM 11060;KM11060;KM-11060;CFTR-F508del Corrector, KM11060;7-CHLORO-4-(4-(4-CHLOROPHENYLSULFONYL)PIPERAZIN-1-YL)QUINOLINE;7-CHLORO-4-[4-[4-CHLOROPHENYL)SULFONYL]-1-PIPERAZINYL]QUINOLINE;Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-;KM 11060,inhibit,KM11060,Inhibitor,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR,KM-11060
CBNumber: CB02446666
Molecular Formula: C19H17Cl2N3O2S
Formula Weight: 422.33
MOL File: 774549-97-2.mol

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KM 11060 Property

storage temp.: Store at RT
solubility: Soluble to 100 mM in DMSO and to 10 mM in ethanol
form: Powder

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 5mg
Price: $90
Updated: 2024/03/01

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 10mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 25mg
Price: $355
Updated: 2024/03/01

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 50mg
Price: $444
Updated: 2024/03/01

Tocris

Product number: 3143
Product name: KM11060
Purity: ≥98%(HPLC)
Packaging: 50
Price: $483
Updated: 2021/12/16

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KM 11060 Chemical Properties,Usage,Production

Uses

KM 11060 is a small molecular corrector of F508del CFTR trafficking, which has potential application in cystic fibrosis therapeutics.

Biological Activity

Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.

KM 11060 Preparation Products And Raw materials

Raw materials

Preparation Products

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KM 11060 Suppliers

China 58 India 1 United Kingdom 1 United States 11 Global 71

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2989
Advantage: 60

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4121
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8449
Advantage: 60

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9638
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 3445
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8003
Advantage: 62

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View Lastest Price from KM 11060 manufacturers

Career Henan Chemical Co

Product: KM 11060 774549-97-2
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

774549-97-2, KM 11060Related Search:

TPP Benzyl alcohol 4-Chloroaniline Sulfenone 4'-Hydroxyacetophenone Chlorobenzene 7-CHLORO-4-N,N-DIMETHYLAMINO-QUINOLINE 1-(4-Pyridyl)piperazine 4-(2-AMINOETHYLAMINO)-PYRIDINE HYDROCHLORIDE KM 11060 7-Chloro-4-piperazinoquinoline 4-(2-AMINOETHYL)AMINOQUINOLINE 7-CHLORO-4-(4-[(4-CHLORO-3-NITROPHENYL)SULFONYL]PIPERAZINO)QUINOLINE 4-(2-AMINOETHYL)AMINO-7-CHLOROQUINOLINE 4-PIPERAZIN-1-YL-QUINOLINE 1-(4-CHLORO-BENZENESULFONYL)-PIPERAZINE

7-CHLORO-4-(4-(4-CHLOROPHENYLSULFONYL)PIPERAZIN-1-YL)QUINOLINE

7-CHLORO-4-[4-[4-CHLOROPHENYL)SULFONYL]-1-PIPERAZINYL]QUINOLINE

KM 11060

CFTR-F508del Corrector, KM11060

KM11060;KM-11060

Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-

KM 11060,inhibit,KM11060,Inhibitor,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR,KM-11060

774549-97-2