KM 11060

ChemicalBook > CAS DataBase List > KM 11060

Product Name: KM 11060
CAS No.: 774549-97-2
Chemical Name: KM 11060
Synonyms: KM 11060;KM11060;KM-11060;CFTR-F508del Corrector, KM11060;7-CHLORO-4-(4-(4-CHLOROPHENYLSULFONYL)PIPERAZIN-1-YL)QUINOLINE;7-CHLORO-4-[4-[4-CHLOROPHENYL)SULFONYL]-1-PIPERAZINYL]QUINOLINE;Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-;KM 11060,inhibit,KM11060,Inhibitor,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR,KM-11060
CBNumber: CB02446666
Molecular Formula: C19H17Cl2N3O2S
Formula Weight: 422.33
MOL File: 774549-97-2.mol

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KM 11060 Property

storage temp.: Store at RT
solubility: Soluble to 100 mM in DMSO and to 10 mM in ethanol
form: Powder

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 5mg
Price: $90
Updated: 2024/03/01

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 10mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 25mg
Price: $355
Updated: 2024/03/01

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 50mg
Price: $444
Updated: 2024/03/01

Tocris

Product number: 3143
Product name: KM11060
Purity: ≥98%(HPLC)
Packaging: 50
Price: $483
Updated: 2021/12/16

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KM 11060 Chemical Properties,Usage,Production

Uses

KM 11060 is a small molecular corrector of F508del CFTR trafficking, which has potential application in cystic fibrosis therapeutics.

Biological Activity

Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.

KM 11060 Preparation Products And Raw materials

Raw materials

Preparation Products

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KM 11060 Suppliers

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View Lastest Price from KM 11060 manufacturers

Career Henan Chemical Co

Product: KM 11060 774549-97-2
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

774549-97-2, KM 11060Related Search:

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7-CHLORO-4-[4-[4-CHLOROPHENYL)SULFONYL]-1-PIPERAZINYL]QUINOLINE

KM 11060

CFTR-F508del Corrector, KM11060

KM11060;KM-11060

Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-

KM 11060,inhibit,KM11060,Inhibitor,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR,KM-11060

774549-97-2