ChemicalBook > CAS DataBase List > KM 11060

KM 11060

Product Name
KM 11060
CAS No.
774549-97-2
Chemical Name
KM 11060
Synonyms
KM 11060;KM11060;KM-11060;CFTR-F508del Corrector, KM11060;7-CHLORO-4-(4-(4-CHLOROPHENYLSULFONYL)PIPERAZIN-1-YL)QUINOLINE;7-CHLORO-4-[4-[4-CHLOROPHENYL)SULFONYL]-1-PIPERAZINYL]QUINOLINE;Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-;KM 11060,inhibit,KM11060,Inhibitor,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR,KM-11060
CBNumber
CB02446666
Molecular Formula
C19H17Cl2N3O2S
Formula Weight
422.33
MOL File
774549-97-2.mol
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KM 11060 Property

storage temp. 
Store at RT
solubility 
Soluble to 100 mM in DMSO and to 10 mM in ethanol
form 
Powder
color 
White to off-white
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23481
Product name
KM 11060
Purity
≥98%
Packaging
5mg
Price
$90
Updated
2024/03/01
Cayman Chemical
Product number
23481
Product name
KM 11060
Purity
≥98%
Packaging
10mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
23481
Product name
KM 11060
Purity
≥98%
Packaging
25mg
Price
$355
Updated
2024/03/01
Cayman Chemical
Product number
23481
Product name
KM 11060
Purity
≥98%
Packaging
50mg
Price
$444
Updated
2024/03/01
Tocris
Product number
3143
Product name
KM11060
Purity
≥98%(HPLC)
Packaging
50
Price
$483
Updated
2021/12/16
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KM 11060 Chemical Properties,Usage,Production

Uses

KM 11060 is a small molecular corrector of F508del CFTR trafficking, which has potential application in cystic fibrosis therapeutics.

Biological Activity

Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.

KM 11060 Preparation Products And Raw materials

Raw materials

Preparation Products

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KM 11060 Suppliers

China 62 India 1 United Kingdom 1 United States 12 Global 76
Shanghai Boyle Chemical Co., Ltd.
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View Lastest Price from KM 11060 manufacturers

Career Henan Chemical Co
Product
KM 11060 774549-97-2
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

774549-97-2, KM 11060Related Search:

TPP Benzyl alcohol 4-Chloroaniline Sulfenone 4'-Hydroxyacetophenone Chlorobenzene 7-CHLORO-4-N,N-DIMETHYLAMINO-QUINOLINE 1-(4-Pyridyl)piperazine 4-(2-AMINOETHYLAMINO)-PYRIDINE HYDROCHLORIDE KM 11060 7-Chloro-4-piperazinoquinoline 4-(2-AMINOETHYL)AMINOQUINOLINE 7-CHLORO-4-(4-[(4-CHLORO-3-NITROPHENYL)SULFONYL]PIPERAZINO)QUINOLINE 4-(2-AMINOETHYL)AMINO-7-CHLOROQUINOLINE 4-PIPERAZIN-1-YL-QUINOLINE 1-(4-CHLORO-BENZENESULFONYL)-PIPERAZINE

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  • KM 11060,inhibit,KM11060,Inhibitor,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR,KM-11060
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