ZONIPORIDE

Product Name
ZONIPORIDE
CAS No.
241800-98-6
Chemical Name
ZONIPORIDE
Synonyms
CP 597396;ZONIPORIDE;Zoniporide hydrochloride hydrate;N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide;N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine;1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-;N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate
CBNumber
CB02448312
Molecular Formula
C17H16N6O
Formula Weight
320.35
MOL File
241800-98-6.mol
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ZONIPORIDE Property

Density 
1.54
storage temp. 
2-8°C
solubility 
H2O: soluble2mg/mL, clear (warmed)
form 
powder
pka
11.44±0.46(Predicted)
color 
white to tan
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0076
Product name
Zoniporide hydrochloride hydrate
Purity
≥98% (HPLC)
Packaging
10mg
Price
$242
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0076
Product name
Zoniporide hydrochloride hydrate
Purity
≥98% (HPLC)
Packaging
50mg
Price
$966
Updated
2024/03/01
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ZONIPORIDE Chemical Properties,Usage,Production

Uses

Zoniporide hydrochloride hydrate has been used for the inhibition of sodium-hydrogen exchanger isoform 1 (NHE-1) in rat models. It has also been used in cytotoxicity assay and to study its effect on lymphocytic choriomeningitis virus multiplication.

Biochem/physiol Actions

Zoniporide is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1). IC50 = 59 nM at NHE-1, vs. 12,000 nM at NHE-2; Zoniporide inhibits NHE-1-dependent Na+ update with IC50 of 14 nM.

ZONIPORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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ZONIPORIDE Suppliers

China 7 The Netherlands 1 United Kingdom 1 United States 1 USA 1 Global 11

241800-98-6, ZONIPORIDERelated Search:

5-ISOPROPYL-1-PHENYL-1H-PYRAZOLE ZONIPORIDE 5-METHYL-1-PHENYL-(1H-PYRAZOL-4-YLMETHYL)AMINE HYDROCHLORIDE

  • N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine
  • CP 597396
  • ZONIPORIDE
  • N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate
  • Zoniporide hydrochloride hydrate
  • 1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-
  • N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide
  • 241800-98-6