ChemicalBook > CAS DataBase List > (+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID

(+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID

Product Name
(+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID
CAS No.
844639-57-2
Chemical Name
(+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID
Synonyms
TM30089;CS-1157;TM30089 Racemate;CAY10471 Racemate;TM 30089;TM-30089;TM30089 (CAY10471);CAY10471 Racemate, 10 mM in DMSO;9H-Carbazole-9-acetic acid, 3-[[(4-fluorophenyl)sulfonyl]MethylaMino]-1,2,3,4-tetrahydro-;(+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID;CAY 10471,CAY10471,TM30089,Inhibitor,CAY-10471,TM 30089,TM-30089,CAY10471 Racemate,inhibit,Prostaglandin Receptor,CAY-10471 Racemate
CBNumber
CB02448675
Molecular Formula
C21H21FN2O4S
Formula Weight
416.47
MOL File
844639-57-2.mol
More
Less

(+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID Property

Melting point:
165-173℃ (dichloromethane )
Boiling point:
639.1±65.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 150 mg/mL (360.17 mM)
form 
Solid
pka
4.33±0.10(Predicted)
color 
Off-white to light yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2743
Product name
TM30089
Purity
≥98% (HPLC)
Packaging
5MG
Price
$124
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2743
Product name
TM30089
Purity
≥98% (HPLC)
Packaging
25MG
Price
$495
Updated
2024/03/01
Biorbyt Ltd
Product number
orb181174
Product name
TM30089
Purity
>98%
Packaging
100mg
Price
$578
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BIO0000169
Product name
TM-30089
Purity
95.00%
Packaging
10MG
Price
$727.65
Updated
2021/12/16
ChemScene
Product number
CS-0007735
Product name
CAY10471Racemate
Purity
99.35%
Packaging
10mg
Price
$140
Updated
2021/12/16
More
Less

(+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID Chemical Properties,Usage,Production

Biological Activity

TM30089 is a ramatroban analog and an orally active, high-affinity, potent and selective prostaglandin D2 receptor 2 (DP2; CRTH2) antagonist (Ki = 0.6 nM/hDP2 against 1.2 nM PGD2; Ki = 1.2 μM/hDP1 against 0.5 nM PGD2, >10 μM/hTP against 5 nM SQ29548) th at blocks PGD2-induced responses in hDP2 transfectants (IP1/βarr IC50 = 1.2/3.0 nM) and exhibits in vivo efficacy in a murine model of renal tubulointerstitial fibrosis (20 mg/kg b.i.d. p.o., starting 4 days before or 3 days after unilateral ureteral obstruction/UUO).

(+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
LKT Laboratories, Inc.
Tel
--
Fax
--
Email
info@lktlabs.com
Country
United States
ProdList
2164
Advantage
64
ChemieTek
Tel
--
Fax
--
Email
info@chemietek.com
Country
United States
ProdList
219
Advantage
50

844639-57-2, (+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACIDRelated Search:


  • TM30089
  • 9H-Carbazole-9-acetic acid, 3-[[(4-fluorophenyl)sulfonyl]MethylaMino]-1,2,3,4-tetrahydro-
  • CS-1157
  • TM30089 (CAY10471)
  • TM 30089;TM-30089
  • CAY10471 Racemate
  • TM30089 Racemate
  • (+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID
  • CAY 10471,CAY10471,TM30089,Inhibitor,CAY-10471,TM 30089,TM-30089,CAY10471 Racemate,inhibit,Prostaglandin Receptor,CAY-10471 Racemate
  • CAY10471 Racemate, 10 mM in DMSO
  • 844639-57-2