4-AMINO-6-MORPHOLINOPYRIMIDINE
- Product Name
- 4-AMINO-6-MORPHOLINOPYRIMIDINE
- CAS No.
- 96225-80-8
- Chemical Name
- 4-AMINO-6-MORPHOLINOPYRIMIDINE
- Synonyms
- 6-MorpholinopyriMidin-4-aMine;4-AMINO-6-MORPHOLINOPYRIMIDINE;6-morpholino-pyrimidin-4-ylamine;6-morpholin-4-ylpyrimidin-4-amine;6-(4-morpholinyl)-4-Pyrimidinamine;4-Pyrimidinamine, 6-(4-morpholinyl)-;4-AMINO-6-MORPHOLINOPYRIMIDINE ISO 9001:2015 REACH
- CBNumber
- CB02453774
- Molecular Formula
- C8H12N4O
- Formula Weight
- 180.21
- MOL File
- 96225-80-8.mol
4-AMINO-6-MORPHOLINOPYRIMIDINE Property
- storage temp.
- 2-8°C(protect from light)
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B497323
- Product name
- 6-Morpholinopyrimidin-4-amine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FA153601
- Product name
- 4-Amino-6-morpholinopyrimidine
- Packaging
- 500mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FA153601
- Product name
- 4-Amino-6-morpholinopyrimidine
- Packaging
- 1g
- Price
- $137.5
- Updated
- 2021/12/16
- Product number
- W9805
- Product name
- 4-Amino-6-morpholinopyrimidine
- Packaging
- 1g
- Price
- $171
- Updated
- 2021/12/16
- Product number
- FA153601
- Product name
- 4-Amino-6-morpholinopyrimidine
- Packaging
- 2g
- Price
- $235
- Updated
- 2021/12/16
4-AMINO-6-MORPHOLINOPYRIMIDINE Chemical Properties,Usage,Production
Synthesis
110-91-8
5305-59-9
96225-80-8
General procedure for the synthesis of 6-N-morpholinopyrimidin-4-amine from 4-amino-6-chloropyrimidine and morpholine: 400 mg of 4-amino-6-chloropyrimidine and 1.51 g (1.5 eq.) of cesium carbonate were added to a reaction flask, 10 mL of N,N-dimethylformamide (DMF) was added as solvent followed by 405 μL (1.5 eq.) of morpholine. The reaction mixture was heated to 100 °C and stirred for 12 hours. After completion of the reaction, an appropriate amount of water was added and the organic phase was extracted with ethyl acetate. The organic phase was washed with saturated brine, dried over anhydrous sodium sulfate, filtered and the solvent was evaporated under reduced pressure. The residue was separated and purified by silica gel column chromatography using methanol/dichloromethane (1:50, v/v) as eluent, resulting in 245 mg of yellow solid product in 44% yield.
References
[1] Journal of Medicinal Chemistry, 2016, vol. 59, # 18, p. 8326 - 8344
[2] Patent: CN105418592, 2016, A. Location in patent: Paragraph 0097; 0098; 0099; 0100; 0101
[3] Journal of the American Chemical Society, 1958, vol. 80, p. 2182,2184
[4] Patent: US4503050, 1985, A
4-AMINO-6-MORPHOLINOPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
4-AMINO-6-MORPHOLINOPYRIMIDINE Suppliers
- Tel
- 001-857-928-2050 or 1-888-588-9418
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- 001-617-206-9595
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View Lastest Price from 4-AMINO-6-MORPHOLINOPYRIMIDINE manufacturers
- Product
- 4-AMINO-6-MORPHOLINOPYRIMIDINE 96225-80-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-13