ChemicalBook > CAS DataBase List > 1-OCTADECYL LPA

1-OCTADECYL LPA

Product Name
1-OCTADECYL LPA
CAS No.
52977-29-4
Chemical Name
1-OCTADECYL LPA
Synonyms
1-OCTADECYL LPA;1-OCTADECYL LYSOPHOSPHATIDIC ACID;1-Octadecyl Lysophosphatidic Acid Exclusive;1-Octadecyl Lysophosphatidic Acid (1-Octadecyl LPA);1,2-Propanediol, 3-(octadecyloxy)-, 1-(dihydrogen phosphate)
CBNumber
CB02455642
Molecular Formula
C21H45O6P
Formula Weight
424.55
MOL File
52977-29-4.mol
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1-OCTADECYL LPA Property

storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS (pH 7.2) ((1:1): 0.5 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10010164
Product name
1-Octadecyl Lysophosphatidic Acid
Purity
≥95%
Packaging
500μg
Price
$26
Updated
2024/03/01
Cayman Chemical
Product number
10010164
Product name
1-Octadecyl Lysophosphatidic Acid
Purity
≥95%
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
10010164
Product name
1-Octadecyl Lysophosphatidic Acid
Purity
≥95%
Packaging
5mg
Price
$192
Updated
2024/03/01
Cayman Chemical
Product number
10010164
Product name
1-Octadecyl Lysophosphatidic Acid
Purity
≥95%
Packaging
10mg
Price
$332
Updated
2024/03/01
AK Scientific
Product number
1374AH
Product name
3-(Octadecyloxy)-1-(dihydrogenphosphate)-1,2-propanediol
Packaging
10mg
Price
$440
Updated
2021/12/16
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1-OCTADECYL LPA Chemical Properties,Usage,Production

Description

1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.1,2 Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.3

References

1. Noguchi, K., Ishii, S., and Shimizu, T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family J. Biol. Chem. 278(28),25600-25606(2003).
2. Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions Trends Cell Biol. 4(6),213-219(1994).
3. Tokumura, A., Sinomiya, J., Kishimoto, S., et al. Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids Biochem. J. 365,617-628(2002).

1-OCTADECYL LPA Preparation Products And Raw materials

Raw materials

Preparation Products

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1-OCTADECYL LPA Suppliers

Shanghai Hongye Biotechnology Co. Ltd
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400-9205774
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China
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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MedBioPharmaceutical Technology Inc
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021-69568360 18916172912
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order@med-bio.cn
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TargetMol Chemicals Inc.
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Shanghai Maclean Biochemical Technology Co., LTD
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Shanghai Yifei Biotechnology Co. , Ltd.
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Resenbio
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Beijing Zhijie Fangyuan Technology Co., Ltd.
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Boao Pike
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Morning Student Science and Technology (Guangzhou) Co., Ltd.
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