1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- Product Name
- 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- CAS No.
- 70641-51-9
- Chemical Name
- 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- Synonyms
- EDELFOSINE;ET-18-OCH3;ET-18-OCH?;Ro 14-5243;NSC 343649;NSC 324368;SN-ET-18-OCH3;18:0-1:0 DIETHER PC;2-O-METHYL PAF C-18;innersalt,4-oxide,(+-)-hydroxide
- CBNumber
- CB2768197
- Molecular Formula
- C27H58NO6P
- Formula Weight
- 523.74
- MOL File
- 70641-51-9.mol
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Property
- storage temp.
- -20°C
- solubility
- ethanol: 15 mg/mL at 45 °C, soluble
- form
- waxy solid
- color
- white
- Water Solubility
- Soluble to 20 mM in water
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- RTECS
- YK0718000
N-Bromosuccinimide Price
- Product number
- SML0332
- Product name
- Edelfosine
- Purity
- ≥95% (HPLC)
- Packaging
- 5mg
- Price
- $144
- Updated
- 2024/03/01
- Product number
- 341207
- Product name
- ET-18-OCH?
- Packaging
- 5mg
- Price
- $144
- Updated
- 2024/03/01
- Product number
- O9262
- Product name
- 1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine
- Purity
- ≥99% (TLC), waxy solid
- Packaging
- 5mg
- Price
- $141
- Updated
- 2022/05/15
- Product number
- SML0332
- Product name
- Edelfosine
- Purity
- ≥95% (HPLC)
- Packaging
- 25mg
- Price
- $568
- Updated
- 2024/03/01
- Product number
- 448513
- Product name
- ET-18-OCH3
- Packaging
- 5mg
- Price
- $305
- Updated
- 2021/12/16
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Usage,Production
Uses
Edelfosine has been used to treat human lung carcinoma A549 cells and study its effects on tuftelin 1 (TUFT1) expression. It is also used to evaluate the cell growth of MCF-7/M cells.
Definition
ChEBI: 1-octadecyl-2-methylglycero-3-phosphocholine is a glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
General Description
Edelfosine has anti-inflammatory, anti-autoimmune, antiparasitic and anti-viral properties. It stimulates eryptosis by cell shrinkage and cell membrane scrambling.
Biochem/physiol Actions
Edelfosine is a synthetic alkyl-lisophospholipid with anti-tumor activity. The compound induces apoptosis in a variety of cancer cells. Edelfosine accumulates in the cell membrane, where it alters lipid composition and induces the co-clustering of lipid rafts and Fas/CD95 death receptor.
storage
Store at -20°C
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers
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