ChemicalBook > CAS DataBase List > 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Product Name
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CAS No.
70641-51-9
Chemical Name
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonyms
EDELFOSINE;ET-18-OCH3;ET-18-OCH?;Ro 14-5243;NSC 343649;NSC 324368;SN-ET-18-OCH3;18:0-1:0 DIETHER PC;2-O-METHYL PAF C-18;innersalt,4-oxide,(+-)-hydroxide
CBNumber
CB2768197
Molecular Formula
C27H58NO6P
Formula Weight
523.74
MOL File
70641-51-9.mol
More
Less

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Property

storage temp. 
-20°C
solubility 
ethanol: 15 mg/mL at 45 °C, soluble
form 
waxy solid
color 
white
Water Solubility 
Soluble to 20 mM in water
More
Less

Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
YK0718000
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0332
Product name
Edelfosine
Purity
≥95% (HPLC)
Packaging
5mg
Price
$144
Updated
2024/03/01
Sigma-Aldrich
Product number
341207
Product name
ET-18-OCH?
Packaging
5mg
Price
$144
Updated
2024/03/01
Sigma-Aldrich
Product number
O9262
Product name
1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine
Purity
≥99% (TLC), waxy solid
Packaging
5mg
Price
$141
Updated
2022/05/15
Sigma-Aldrich
Product number
SML0332
Product name
Edelfosine
Purity
≥95% (HPLC)
Packaging
25mg
Price
$568
Updated
2024/03/01
Usbiological
Product number
448513
Product name
ET-18-OCH3
Packaging
5mg
Price
$305
Updated
2021/12/16
More
Less

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Usage,Production

Uses

Edelfosine has been used to treat human lung carcinoma A549 cells and study its effects on tuftelin 1 (TUFT1) expression. It is also used to evaluate the cell growth of MCF-7/M cells.

Definition

ChEBI: 1-octadecyl-2-methylglycero-3-phosphocholine is a glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

General Description

Edelfosine has anti-inflammatory, anti-autoimmune, antiparasitic and anti-viral properties. It stimulates eryptosis by cell shrinkage and cell membrane scrambling.

Biochem/physiol Actions

Edelfosine is a synthetic alkyl-lisophospholipid with anti-tumor activity. The compound induces apoptosis in a variety of cancer cells. Edelfosine accumulates in the cell membrane, where it alters lipid composition and induces the co-clustering of lipid rafts and Fas/CD95 death receptor.

storage

Store at -20°C

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Synchem OHG
Tel
+49 5662 408730
Fax
+49 5662 4087320
Email
info@synchem.de
Country
Germany
ProdList
4705
Advantage
70
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6083
Advantage
56
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31121
Advantage
58
Guangdong Wengjiang Chemical Reagent Co.,Ltd.
Tel
0751-2815983 13927872582
Fax
0751-2886750
Email
3008325437@qq.com
Country
China
ProdList
3917
Advantage
58

70641-51-9, 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINERelated Search:


  • 4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-Trioxa-4-phosphaheptacosan-1-aminium 4-oxide
  • NSC 324368
  • NSC 343649
  • Racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine
  • Ro 14-5243
  • ET-18-OCH?
  • ET-18-OCH3
  • EDELFOSINE
  • 18:0-1:0 DIETHER PC
  • 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • ET-18-OCH - CAS 70641-51-9 - Calbiochem
  • 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
  • 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
  • 2-O-METHYL PAF C-18
  • 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide
  • SN-ET-18-OCH3
  • 3,5,9-trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-7-methoxy-n,n,n-trimethyl
  • innersalt,4-oxide,(+-)-hydroxide
  • rac-1-octadecyl-2-methoxyglycero-3-phosphocholine
  • (2-methoxy-3-octadecoxy-propyl) 2-(trimethylazaniumyl)ethyl phosphate
  • (2-methoxy-3-octadecoxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
  • (2-methoxy-3-stearyloxy-propyl) 2-(trimethylammonio)ethyl phosphate
  • Edelfosine, ALP, Ro 14-5243, ET-18-OMe, ET 18-OCH3, NSC 324368, NSC 343649
  • 1-Octadecyl-2-methylglycero-3-phosphorylcholine
  • 70641-51-9
  • C27H58NO6P