CYNARIN

Product Name: CYNARIN
CAS No.: 19870-46-3
Chemical Name: CYNARIN
Synonyms: 19870-46-3 CYNARIN;1,3-Dicaffeoylquinic acid;Dicaffeoylquinic Acid, 1,5-;1,5-Dicaffeoylquinic acid-RM;1,5-di-O-Caffeoylquinic acid;(1S,3R,4R,5R)-1,3-O-Dicaffeoylquinic acid;(1S,3R,4R,5R)-1,3-Bis[3-(3,4-dihydroxyphenyl)acryloyloxy]-4,5-dihydroxycyclohexanecarboxylic acid;(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylicaci;(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylic acid;Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-
CBNumber: CB02457303
Molecular Formula: C25H24O12
Formula Weight: 516.45
MOL File: 19870-46-3.mol

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CYNARIN Property

Boiling point:: 819.9±65.0 °C(Predicted)
Density: 1?+-.0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: soluble5mg/mL, clear, colorless to light yellow
form: Solid
pka: 2.50±0.50(Predicted)
color: white to off-white
Stability:: Hygroscopic

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL82221
Product name: 1,5-Dicaffeoylquinic acid
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $539
Updated: 2024/03/01

Sigma-Aldrich

Product number: 16917
Product name: 1,5-Dicaffeoylquinic acid
Purity: analytical standard
Packaging: 5mg
Price: $659
Updated: 2022/05/15

Cayman Chemical

Product number: 25050
Product name: 1,5-Dicaffeoylquinic Acid
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 25050
Product name: 1,5-Dicaffeoylquinic Acid
Purity: ≥98%
Packaging: 5mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 25050
Product name: 1,5-Dicaffeoylquinic Acid
Purity: ≥98%
Packaging: 10mg
Price: $249
Updated: 2024/03/01

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CYNARIN Chemical Properties,Usage,Production

Description

1,5-Dicaffeoylquinic acid (1,5-DCQA) has been found in A. montana and is an HIV-1 integrase inhibitor and free radical scavenger. 1,5-DCQA inhibits HIV-1 integrase 3'' end processing, end joining, and disintegration with IC₅₀ values of 0.35, 0.56, and 0.84 μg/ml, respectively. It also inhibits HIV-1 replication in MT-2 T lymphoblastoid cells with an ED₅₀value of 2 μg/ml. 1,5-DCQA (0.25-1 μM) reduces the level of free radicals released from human polymorphonuclear (PMN) cells stimulated by N-formyl-Met-Leu-Phe (fMLP; ) in a dose-dependent manner. It also dose-dependently increases cell survival and glutathione (GSH) levels and decreases reactive oxygen species (ROS) production and lactate dehydrogenase (LDH) release in an oxygen-glucose deprivation/reperfusion assay in rat cerebral astrocytes when used at concentrations ranging from 5 to 100 μM.

Uses

1,5-Dicaffeoylquinic Acid acts as an anti-hyperlipidemic agent. In addition, acts as a neuroprotective agent against amyloid-β toxicity in the treatement of Alzheimer’s.

CYNARIN Preparation Products And Raw materials

Raw materials

Preparation Products

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CYNARIN Suppliers

China 105 Germany 1 India 1 United Kingdom 2 United States 13 Global 122

TransMIT GmbH PlantMetaChem

Tel: +49-172-1024293
Fax: +49-(0)6422-938149
Email: pmc@transmit.de
Country: Germany
ProdList: 142
Advantage: 60

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View Lastest Price from CYNARIN manufacturers

Shanghai Standard Technology Co., Ltd.

Product: 1,5-Dicaffeoylquinic acid 19870-46-3
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-28

Career Henan Chemical Co

Product: CYNARIN 19870-46-3
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-13

19870-46-3, CYNARINRelated Search:

Cynarin Isochlorogenic Acid B Cryptochlorogenic acid CAFTARIC ACID 1-Caffeoylquinic acid Isochlorogenic acid A Chlorogenic acid 1,3,5-Tricaffeoylquinic acid Isochlorogenic acid C 2,3,4,5-Tetracaffeoyl-D-Glucaric acid Neochlorogenic acid

1,3-Dicaffeoylquinic acid

(1S,3R,4R,5R)-1,3-Bis[3-(3,4-dihydroxyphenyl)acryloyloxy]-4,5-dihydroxycyclohexanecarboxylic acid

Dicaffeoylquinic Acid, 1,5-

(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylic acid

1,5-di-O-Caffeoylquinic acid

Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-

(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylicaci

19870-46-3 CYNARIN

(1S,3R,4R,5R)-1,3-O-Dicaffeoylquinic acid

CYNARIN|||Cyclohexanecarboxyli?c acid, 1,?3-?bis[[3-?(3,?4-?dihydroxyphenyl)?-?1-?oxo-?2-?propen-?1-?yl]?oxy]?-?4,?5-?dihydroxy-?, (1S,?3R,?4R,?5R)?-|||1,3-O-Dicaffeoylquinic acid|||1,5-Dicaffeoylquinic acid

1,5-Dicaffeoylquinic acid-RM

19870-46-3

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract