Isochlorogenic acid A

Product Name: Isochlorogenic acid A
CAS No.: 2450-53-5
Chemical Name: Isochlorogenic acid A
Synonyms: 3,5-Dicaffeoylquinic acid;3,5-CQA;CJ 4-16-4;Isochloric acid A;Isochlorogenic acid A;3,5-Dicaffeylquinic acid;ISOCHLOROGENIC ACID A(SH);3',5'-Isochlorogenic acid A;3,5-Dicaffeoylquinic acid-RM;Quinic acid 3,5-di-O-caffeate
CBNumber: CB81040694
Molecular Formula: C25H24O12
Formula Weight: 516.46
MOL File: 2450-53-5.mol

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Isochlorogenic acid A Property

Melting point:: >175°C (dec.)
Boiling point:: 826.2±65.0 °C(Predicted)
Density: 1?+-.0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Off-white to yellow/brown crystalline solid.
pka: 3.54±0.50(Predicted)
color: Off-White to Pale Yellow
Stability:: Hygroscopic
InChIKey: KRZBCHWVBQOTNZ-PSEXTPKNSA-N

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Safety

Safety Statements: 24/25
WGK Germany: 3
RTECS: GU8403966
HS Code: 29189900

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00131
Product name: 3,5-Di-caffeoylquinic acid
Purity: ≥95% (LC/MS-ELSD)
Packaging: 1mg
Price: $306
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL80426
Product name: 3,5-Dicaffeoylquinic acid
Purity: phyproof Reference Substance
Packaging: 10mg
Price: $777
Updated: 2024/03/01

Cayman Chemical

Product number: 24964
Product name: 3,5-Dicaffeoylquinic Acid
Purity: ≥98%
Packaging: 5mg
Price: $79
Updated: 2024/03/01

Cayman Chemical

Product number: 24964
Product name: 3,5-Dicaffeoylquinic Acid
Purity: ≥98%
Packaging: 10mg
Price: $141
Updated: 2024/03/01

Cayman Chemical

Product number: 24964
Product name: 3,5-Dicaffeoylquinic Acid
Purity: ≥98%
Packaging: 25mg
Price: $312
Updated: 2024/03/01

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Isochlorogenic acid A Chemical Properties,Usage,Production

Description

3,5-Dicaffeoylquinic acid (3,5-DCQA) is a natural phenolic compound that has been found in L. japonica, I. kaushue, and other plants. It has antioxidant, anti-inflammatory, and antiviral biological activities. 3,5-DCQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay (IC₅₀ = 71.8 μM) and inhibits superoxide production in human neutrophils activated by N-formyl-Met-Leu-Phe (fMLF) and cytochalasin B (IC₅₀ = 1.92 μM). It inhibits HIV-1 integrase 3''-end processing, strand transfer, and disintegration in a cell-free assay (IC₅₀s = 0.33, 0.34, and 0.66 μg/ml, respectively) and inhibits HIV-1-induced cytotoxicity in MT-2 cells (ED₅₀ = 1 μg/ml). In vivo, 3,5-DCQA (25 mg/kg) protects mice from acute lung injury induced by LPS and decreases neutrophil count in bronchoalveolar lavage fluid (BALF).

Uses

Isochlorogenic Acid A is a phenolic compound shown to provide protection against oxidative stress cells. DNA protective agent.

Definition

ChEBI: 3,5-di-O-caffeoyl quinic acid is a carboxylic ester that is the diester obtained by the condensation of the hydroxy groups at positions 3 and 5 of (-)-quinic acid with the carboxy group of trans-caffeic acid. Isolated from Brazilian propolis and Suaeda glauca, it exhibits hepatoprotective and cytotoxic activities. It has a role as a metabolite, a hepatoprotective agent and an antineoplastic agent. It is a cyclitol carboxylic acid and a carboxylic ester. It is functionally related to a (-)-quinic acid and a trans-caffeic acid.

Isochlorogenic acid A Preparation Products And Raw materials

Raw materials

Preparation Products

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Isochlorogenic acid A Suppliers

China 198 Germany 2 India 1 Switzerland 1 United Kingdom 2 United States 18 Global 222

Nanjing Yuanzhi Biotechnology Co. Ltd.

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J & K SCIENTIFIC LTD.

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Chengdu Ai Keda Chemical Technology Co., Ltd.

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Chengdu Biopurify Phytochemicals Ltd.

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Email: cwb1@biopurify.cn
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View Lastest Price from Isochlorogenic acid A manufacturers

Career Henan Chemical Co

Product: Isochlorogenic acid A 2450-53-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 25kg
Release date: 2019-07-12

2450-53-5, Isochlorogenic acid ARelated Search:

EPA Cryptochlorogenic acid Ethyl 2-(Chlorosulfonyl)acetate Folic acid Citric acid Stearic acid Diethyl succinosuccinate Dibutyryl adenosine cyclophosphate calcium Isochlorogenic acid C,Isochlorogenic acid C，4,5-Dicaffeoylquinic acid Isochlorogenic Acid B Taxifolin Isochlorogenic acid C (E,E)-3,5-Di-O-caffeoylquinic acid Ascoric Acid Fluorescein isothiocyanate isomer I [1S-(1alpha,3beta,4beta,5alpha)]-3-[[3-(3,4-dihydroxyphenyl)-1-oxoallyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid CYCLOHEPTYL ISOTHIOCYANATE Ethoxycarbonyl Isothiocyanate

3,5-Dicaffeoylquinic acid

Isochlorogenic acid A

Isochlorogenic acid A，3,5-Dicaffeoylquinic acid

3α,5β-Bis[[1-oxo-3-(3,4-dihydroxyphenyl)-2-propenyl]oxy]-1α,4α-dihydroxycyclohexane-1-carboxylic acid

1α,4α-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)propenoyloxy]cyclohexanecarboxylic acid

1β,4β-Dihydroxy-3β,5α-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1α-cyclohexanecarboxylic acid

1β,4β-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)acryloyloxy]cyclohexane-1-carboxylic acid

1β,4β-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)propenoyloxy]cyclohexanecarboxylic acid

3β,5α-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1β,4β-dihydroxycyclohexanecarboxylic acid

3,5-Dicaffeylquinic acid

CJ 4-16-4

Quinic acid 3,5-di-O-caffeate

ISOCHLOROGENIC ACID A(SH)

Isochlorogenic acid A, froM Lonicera japonica

Isochlorogenic acid A, 98%, from Lonicera japonica Thunb.

3,5-Di-O-caffeoylquinic acid，Isochlorogenic acid A

Isochlorogenic acid A, 98%, from Lonicera japonica

3,5-CQA

Cyclohexanecarboxylic acid, 3,5-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,4-dihydroxy-, (1α,3R,4α,5R)-

3',5'-Isochlorogenic acid A

(3R,5R)-3,5-Bis{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-1,4-dihydroxycyclohexanecarboxylic acid

Isochloric acid A

(1R,3R,4S,5R)-3,5-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4-dihydroxy-3-methylcyclohexane-1-carboxylic acid

3,5-Dicaffeoylquinic acid-RM

Isochlorogenic acid A in Methanol

2450-53-5

The group of Chlorogenic acid

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Aromatic Phenols