Isochlorogenic acid A
- Product Name
- Isochlorogenic acid A
- CAS No.
- 2450-53-5
- Chemical Name
- Isochlorogenic acid A
- Synonyms
- 3,5-Dicaffeoylquinic acid;3,5-CQA;CJ 4-16-4;Isochloric acid A;Isochlorogenic acid A;3,5-Dicaffeylquinic acid;ISOCHLOROGENIC ACID A(SH);3',5'-Isochlorogenic acid A;3,5-Dicaffeoylquinic acid-RM;Quinic acid 3,5-di-O-caffeate
- CBNumber
- CB81040694
- Molecular Formula
- C25H24O12
- Formula Weight
- 516.46
- MOL File
- 2450-53-5.mol
Isochlorogenic acid A Property
- Melting point:
- >175°C (dec.)
- Boiling point:
- 826.2±65.0 °C(Predicted)
- Density
- 1?+-.0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Off-white to yellow/brown crystalline solid.
- pka
- 3.54±0.50(Predicted)
- color
- Off-White to Pale Yellow
- Stability:
- Hygroscopic
- InChIKey
- KRZBCHWVBQOTNZ-PSEXTPKNSA-N
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- RTECS
- GU8403966
- HS Code
- 29189900
N-Bromosuccinimide Price
- Product number
- SMB00131
- Product name
- 3,5-Di-caffeoylquinic acid
- Purity
- ≥95% (LC/MS-ELSD)
- Packaging
- 1mg
- Price
- $306
- Updated
- 2024/03/01
- Product number
- PHL80426
- Product name
- 3,5-Dicaffeoylquinic acid
- Purity
- phyproof Reference Substance
- Packaging
- 10mg
- Price
- $777
- Updated
- 2024/03/01
- Product number
- 24964
- Product name
- 3,5-Dicaffeoylquinic Acid
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $79
- Updated
- 2024/03/01
- Product number
- 24964
- Product name
- 3,5-Dicaffeoylquinic Acid
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $141
- Updated
- 2024/03/01
- Product number
- 24964
- Product name
- 3,5-Dicaffeoylquinic Acid
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $312
- Updated
- 2024/03/01
Isochlorogenic acid A Chemical Properties,Usage,Production
Description
3,5-Dicaffeoylquinic acid (3,5-DCQA) is a natural phenolic compound that has been found in L. japonica, I. kaushue, and other plants. It has antioxidant, anti-inflammatory, and antiviral biological activities. 3,5-DCQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay (IC50 = 71.8 μM) and inhibits superoxide production in human neutrophils activated by N-formyl-Met-Leu-Phe (fMLF) and cytochalasin B (IC50 = 1.92 μM). It inhibits HIV-1 integrase 3''-end processing, strand transfer, and disintegration in a cell-free assay (IC50s = 0.33, 0.34, and 0.66 μg/ml, respectively) and inhibits HIV-1-induced cytotoxicity in MT-2 cells (ED50 = 1 μg/ml). In vivo, 3,5-DCQA (25 mg/kg) protects mice from acute lung injury induced by LPS and decreases neutrophil count in bronchoalveolar lavage fluid (BALF).
Uses
Isochlorogenic Acid A is a phenolic compound shown to provide protection against oxidative stress cells. DNA protective agent.
Definition
ChEBI: 3,5-di-O-caffeoyl quinic acid is a carboxylic ester that is the diester obtained by the condensation of the hydroxy groups at positions 3 and 5 of (-)-quinic acid with the carboxy group of trans-caffeic acid. Isolated from Brazilian propolis and Suaeda glauca, it exhibits hepatoprotective and cytotoxic activities. It has a role as a metabolite, a hepatoprotective agent and an antineoplastic agent. It is a cyclitol carboxylic acid and a carboxylic ester. It is functionally related to a (-)-quinic acid and a trans-caffeic acid.
Isochlorogenic acid A Preparation Products And Raw materials
Raw materials
Preparation Products
Isochlorogenic acid A Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from Isochlorogenic acid A manufacturers
- Product
- Isochlorogenic acid A 2450-53-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 25kg
- Release date
- 2019-07-12