(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL

Product Name: (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL
CAS No.: 134234-12-1
Chemical Name: (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL
Synonyms: CP-101;CP 98113;CP 101606;1-((1S,2S);Traxoprodil;propan-2-yl);(+)-CP 101,606;Traxoprodil(CP-101,606);CP-101,606 >=98% (HPLC);CP-101;606;CP 101606;CP101606
CBNumber: CB02461182
Molecular Formula: C20H25NO3
Formula Weight: 327.42
MOL File: 134234-12-1.mol

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(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Property

Boiling point:: 534.4±50.0 °C(Predicted)
Density: 1.228
storage temp.: 2-8°C
solubility: DMSO: ≥35mg/mL
pka: 9.99±0.26(Predicted)
form: powder
color: white to tan
optical activity: [α]/D +50 to +60° (c=1, MeOH)

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Safety

Hazard Codes: T,N
Risk Statements: 25-36-50
Safety Statements: 26-45-61
RIDADR: 2811
WGK Germany: 3
HazardClass: IRRITANT
PackingGroup: Ⅲ

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0053
Product name: CP-101,606
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $125
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0053
Product name: CP-101,606
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $526
Updated: 2024/03/01

Sigma-Aldrich

Product number: 5.04523
Product name: CP-101,606 - CAS 134234-12-1 - Calbiochem
Packaging: 5mg
Price: $191
Updated: 2022/05/15

Cayman Chemical

Product number: 23884
Product name: (+)-CP 101,606
Purity: ≥98%
Packaging: 5mg
Price: $72
Updated: 2024/03/01

Cayman Chemical

Product number: 23884
Product name: (+)-CP 101,606
Purity: ≥98%
Packaging: 10mg
Price: $93
Updated: 2024/03/01

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(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Chemical Properties,Usage,Production

Uses

Traxoprodil (CP101,606) is a potent and selective NMDA antagonist and protect hippocampal neurons with an IC50 of 10 nM.

Uses

CP-101,606 has been used as a N-methyl-D-aspartate (NMDA)?receptor antagonist to study its role in recovery of spinal cord injuries.

brand name

Traxoprodil is INN.

General Description

CP-101,606 (Traxoprodil) is a substituted 4-phenylpiperidine and is localized in the fore brain neurons.

Biochem/physiol Actions

Traxoprodil (CP-101,606) is a potent noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, selective for the NR2B subunit. It has been shown to be neuroprotective in animal models of brain injury and stroke.

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Suppliers

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134234-12-1, (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOLRelated Search:

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL 4,4,5,5-TetraMethyl-2-(3-triphenylen-2-yl-phenyl)-[1,3,2]dioxaborolane Butyl acetate Ethyl acetate 1-isopropylpiperidin-4-ol 1-phenethylpiperidin-4-ol (1S,2S)-(+)-N-METHYLPSEUDOEPHEDRINE CHEMBRDG-BB 4003161 1-Phenethyl-4-phenyl-4-piperidinol 1-[(1S,2S)-2-HYDROXY-1-METHYL-2-(4-TRIISOPROPYLSILANYLOXY-PHENYL)-ETHYL]-4-PHENYL-PIPERIDIN-4-OL alpha-[1-(Butylmethylamino)ethyl]-benzyl alcohol 4-HYDROXY-1-PIPERIDINEETHANOL 96 (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL

1-((1S,2S)

-1-Hydroxy-1-(4-hydroxyphenyl)

propan-2-yl)

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL

CP 101606

1-[(1S,2S)-2-Hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]-4-phenylpiperidin-4-ol

(1s,2s)-1-[4-[ hydroxylphenyl]- 2- ( 4-hydroxy-4-pheny1piperidino)-1- propanol

1-((1S,2S)-1-Hydroxy-1-(4-hydroxyphenyl)propan-2-yl)-4-phenylpiperidin-4-ol

CP-101

CP-101;606;CP 101606;CP101606

[S-(R*,R*)]-4-Hydroxy-alpha-(4-hydroxyphenyl)-beta-methyl-4-phenyl-1-piperidineethanol

CP 98113

Traxoprodil

Traxoprodil(CP-101,606)

1-Piperidineethanol, 4-hydroxy-α-(4-hydroxyphenyl)-β-methyl-4-phenyl-, (αS,βS)-

CP-101,606 >=98% (HPLC)

(+)-CP 101,606

iGluR,Ionotropic glutamate receptors,inhibit,Inhibitor,Traxoprodil

CP101606，CP101606/Traxoprodil,CO-98113(racemate)

134234-12-1