Prostaglandin E1 Impurity 4

Product Name: Prostaglandin E1 Impurity 4
CAS No.: 21003-46-3
Chemical Name: Prostaglandin E1 Impurity 4
Synonyms: 8-Iso-PGE1;OVINONIC ACID;(-)-8-epi-PGE1;8-Epiprostaglandin E1;8-epi-Prostaglandin E1;8-ISO PROSTAGLANDIN E1;Alprostadil EP Impurity F;GMVPRGQOIOIIMI-JCPCGATGSA-N;Prostaglandin (Alprostadil) EP Impurity F;9-oxo-11α,15S-dihydroxy-(8β)-prost-13E-en-1-oic acid
CBNumber: CB0246123
Molecular Formula: C20H34O5
Formula Weight: 354.48
MOL File: 21003-46-3.mol

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Prostaglandin E1 Impurity 4 Property

Melting point:: 77-79 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling point:: 529.3±50.0 °C(Predicted)
Density: 1.131±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)
form: A light yellow crystalline solid
pka: 4.77±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 13360
Product name: 8-iso Prostaglandin E1
Purity: ≥98%
Packaging: 500μg
Price: $51
Updated: 2024/03/01

Cayman Chemical

Product number: 13360
Product name: 8-iso Prostaglandin E1
Purity: ≥98%
Packaging: 1mg
Price: $87
Updated: 2024/03/01

Cayman Chemical

Product number: 13360
Product name: 8-iso Prostaglandin E1
Purity: ≥98%
Packaging: 5mg
Price: $354
Updated: 2024/03/01

Cayman Chemical

Product number: 13360
Product name: 8-iso Prostaglandin E1
Purity: ≥98%
Packaging: 10mg
Price: $606
Updated: 2024/03/01

TRC

Product number: I918350
Product name: 8-IsoprostaglandinE1
Packaging: 25mg
Price: $1125
Updated: 2021/12/16

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Prostaglandin E1 Impurity 4 Chemical Properties,Usage,Production

Description

Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E₁ (8-iso PGE₁) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF_2α.

Uses

Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2α.[Cayman Chemical]

Uses

8-Isoprostaglandin E1 has vasodilatory and electrophysiological actions porcine coronary artery. It also inhibits acetylcholine release from parasympathetic nerves innervating guinea-pig trachea mediation by prostanoid EP3 receptors.

Definition

ChEBI: 8-Isoprostaglandin E1 is a prostanoid.

References

[1] J D MORROW. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1990, 87 23: 9383-9387. DOI: 10.1073/pnas.87.23.9383
[2] TAYLOR P L. The 8-isoprostaglandins: Evidence for eight compounds in human semen[J]. Prostaglandins, 1979, 17 2: Pages 259-267. DOI: 10.1016/0090-6980(79)90046-7
[3] J NAKANO J M K. Effects of 8-isoprostaglandin E1 on the systemic and pulmonary circulations in dogs.[J]. Proceedings of the Society for Experimental Biology and Medicine, 1970, 133 4: 1314-1317. DOI: 10.3181/00379727-133-34679
[4] CATHERINE A. OPERE. Dual Effect of Isoprostanes on the Release of [3H]D-Aspartate from Isolated Bovine Retinae: Role of Arachidonic Acid Metabolites[J]. Neurochemical Research, 2005, 30 1: 129-137. DOI: 10.1007/s11064-004-9694-3

Prostaglandin E1 Impurity 4 Preparation Products And Raw materials

Raw materials

Preparation Products

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21003-46-3, Prostaglandin E1 Impurity 4Related Search:

Prostaglandin E1 Impurity 4 Isoprostane Related Compound 1 PROSTAGLANDIN A2 8-ISOPROSTANE PROSTAGLANDIN A1 6-KETO-PROSTAGLANDIN F1ALPHA Prostaglandin E1 Impurity 2 15-KETO PROSTAGLANDIN E1 15(R)-PROSTAGLANDIN E1 15(R)-PROSTAGLANDIN E2 11BETA-PROSTAGLANDIN E2 Prostaglandin E1 PROSTAGLANDIN H2 Prostaglandin E2 Undecenoic acid 10TR-PENTADECENOIC ACID 8-ISO PROSTAGLANDIN E1 TRANS-13-OCTADECENOIC ACID

GMVPRGQOIOIIMI-JCPCGATGSA-N

9-oxo-11α,15S-dihydroxy-(8β)-prost-13E-en-1-oic acid

OVINONIC ACID

9-Oxo-11aloha,15S-dihydroxy-(8beta)-prost-13E-en-1-oic acid

7-[(1S,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid

(-)-8-epi-PGE1

(8β,13E,15S)-11α,15-Dihydroxy-9-oxoprost-13-en-1-oic acid

8-Epiprostaglandin E1

8-epi-Prostaglandin E1

8-Iso-PGE1

9-OXO-11ALPHA,15S-DIHYDROXY-(8BETA)-PROST-13E-EN-1-OIC ACID

8-ISO PROSTAGLANDIN E1

Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (8β,11α,13E,15S)-

Alprostadil EP Impurity F

f.7-[(1S,2R,3R)-3-hydroxy-2-[(1e,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoicacid(8-epiprostaglandine1),

Prostaglandin (Alprostadil) EP Impurity F

21003-46-3