2-Chloro-5-iodopyrazine
Uses Application- Product Name
- 2-Chloro-5-iodopyrazine
- CAS No.
- 1057216-55-3
- Chemical Name
- 2-Chloro-5-iodopyrazine
- Synonyms
- 2-Chloro-5-iodopyrazine;2-Chloro-5-iodipyrazine;Pyrazine, 2-chloro-5-iodo-
- CBNumber
- CB02470067
- Molecular Formula
- C4H2ClIN2
- Formula Weight
- 240.43
- MOL File
- 1057216-55-3.mol
2-Chloro-5-iodopyrazine Property
- Boiling point:
- 250.2±35.0 °C(Predicted)
- Density
- 2.187±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- -4.25±0.10(Predicted)
- Appearance
- White to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- X8773
- Product name
- 2-Chloro-5-iodopyrazine
- Packaging
- 250mg
- Price
- $164
- Updated
- 2021/12/16
- Product number
- HCH0357787
- Product name
- 2-CHLORO-5-IODOPYRAZINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.17
- Updated
- 2021/12/16
- Product number
- 072342
- Product name
- 2-Chloro-5-iodopyrazine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $693
- Updated
- 2021/12/16
- Product number
- 072342
- Product name
- 2-Chloro-5-iodopyrazine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1498
- Updated
- 2021/12/16
- Product number
- A175503
- Product name
- 2-Chloro-5-iodopyrazine
- Purity
- 95%
- Packaging
- 100mg
- Price
- $56
- Updated
- 2021/12/16
2-Chloro-5-iodopyrazine Chemical Properties,Usage,Production
Uses
2-Chloro-5-iodopyrazine is a pharmaceutical intermediate that has been reported in the literature to be used in the preparation of estrogen receptor covalent antagonists and orexin receptor modulators.
Application
2-Chloro-5-iodopyrazine can be used to prepare tetrasubstituted olefin compounds having the following structure. These compounds are estrogen receptor covalent antagonists. These compounds can be used to inhibit the growth of cell cultures of MCF7ER-alpha (wild-type) and MCF7ER-alpha (Y537S mutant) cells. Other compounds known to inhibit the growth of cell cultures of MCF7ER-alpha (wild-type) cells (e.g., tamoxifen, raloxifene, and fulvestrant) are currently used to treat breast cancer in human patients. Therefore, the compounds disclosed herein can be used to treat breast cancer expressing ER-alpha in human patients, and specifically, to treat breast cancer expressing Y537S mutant ER-alpha in human patients.
2-Chloro-5-iodopyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloro-5-iodopyrazine Suppliers
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