Ethyl 4-Ethynylbenzoate

Product Name: Ethyl 4-Ethynylbenzoate
CAS No.: 10602-03-6
Chemical Name: Ethyl 4-Ethynylbenzoate
Synonyms: Ethyl 4-Ethynylbenzoate;Ethyl 4-Ethynylbenzoate(WX686207);4-(Ethoxycarbonyl)phenylacetylene;(p-Ethoxycarbonylphenyl)acetylene;4-Ethynyl-benzoic acid ethyl ester;Ethyl 4-ethynylbenzoate - [E54339];Benzoic acid, 4-ethynyl-, ethyl ester
CBNumber: CB02518211
Molecular Formula: C11H10O2
Formula Weight: 174.2
MOL File: 10602-03-6.mol

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Ethyl 4-Ethynylbenzoate Property

Melting point:: 28 °C
Boiling point:: 257.1±23.0 °C(Predicted)
Density: 1.08±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
Appearance: Colorless to light yellow <28 °C Solid,>28 °C Liquid

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Safety

HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical

Product number: E1501
Product name: Ethyl 4-Ethynylbenzoate
Purity: min. 98.0 %
Packaging: 1G
Price: $112
Updated: 2025/07/31

TCI Chemical

Product number: E1501
Product name: Ethyl 4-Ethynylbenzoate
Purity: min. 98.0 %
Packaging: 5G
Price: $336
Updated: 2025/07/31

Usbiological

Product number: 449259
Product name: Ethyl 4-ethynylbenzoate
Packaging: 10mg
Price: $305
Updated: 2021/12/16

TRC

Product number: E917888
Product name: Ethyl4-ethynylbenzoate
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR951484
Product name: Ethyl 4-ethynylbenzoate
Packaging: 100mg
Price: $135
Updated: 2021/12/16

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Ethyl 4-Ethynylbenzoate Chemical Properties,Usage,Production

Synthesis

150969-54-3

10602-03-6

The general procedure for the synthesis of ethyl 4-alkynylbenzoate from the compound (CAS:150969-54-3) is as follows: firstly, the desired aryl-substituted terminal acetylene (5) was prepared using the Sonogashira reaction [1] as a precursor for the synthesis of betulinic acid 1,2,3-triazole library. Some of the acetylene (5a, 5b, 5c, 5g) can be purchased directly from commercial sources. This was done as follows: under argon protection, iodide 6 (500 mg) was reacted with trimethylmethylsilylacetylene (1.5 eq.) in the presence of Pd(PPh3)2Cl2 (2 mol%), CuI (4 mol%), and triethylamine (0.5 mL) in dry DMF at room temperature to produce intermediate 7. Subsequently, intermediate 7 was formed by reaction of iodide 6 with trimethylsilylacetylene (1.5 eq.) dissolved in anhydrous methanol (4.0 mL ) in anhydrous methanol (4.0 mL), the demethylsilylation reaction was achieved by treating intermediate 7 with a solution of K2CO3 (1 equiv.) to ultimately yield terminal acetylene 5.

References

[1] Chemistry - A European Journal, 2011, vol. 17, # 34, p. 9320 - 9325
[2] European Journal of Medicinal Chemistry, 2015, vol. 102, p. 93 - 105
[3] Patent: WO2009/149381, 2009, A2. Location in patent: Page/Page column 32
[4] Journal of Polymer Science, Part A: Polymer Chemistry, 2011, vol. 49, # 1, p. 211 - 224
[5] Journal of the American Chemical Society, 2015, vol. 137, # 1, p. 413 - 419

Ethyl 4-Ethynylbenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 4-Ethynylbenzoate Suppliers

China 71 India 6 United States 5 Global 82

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View Lastest Price from Ethyl 4-Ethynylbenzoate manufacturers

Career Henan Chemical Co

Product: Ethyl 4-Ethynylbenzoate 10602-03-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-12-25

10602-03-6, Ethyl 4-EthynylbenzoateRelated Search:

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(p-Ethoxycarbonylphenyl)acetylene

4-(Ethoxycarbonyl)phenylacetylene

Ethyl 4-Ethynylbenzoate(WX686207)

Benzoic acid, 4-ethynyl-, ethyl ester

Ethyl 4-ethynylbenzoate - [E54339]

10602-03-6