Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)-

Product Name: Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)-
CAS No.: 148553-51-9
Chemical Name: Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)-
Synonyms: (R)-3-(AMinoMethyl)-5-Methylhexanoic acid;EOS-60963;PD 144550;ent-Pregabalin;PGL-R-isomer(IMP);Pregabalin R-Isomer;Pregaballin R-Isomer;Pregabalin IMpurity V;Pregabalin EP impurity B;(R)-Isomer of Pregabalin
CBNumber: CB02519117
Molecular Formula: C8H17NO2
Formula Weight: 159.23
MOL File: 148553-51-9.mol

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Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- Property

Boiling point:: 274.0±23.0 °C(Predicted)
Density: 0.997±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Methanol (Slightly), Water (Slightly)
form: Solid
pka: 4.23±0.10(Predicted)
color: White
Major Application: pharmaceutical
InChI: 1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m1/s1
InChIKey: AYXYPKUFHZROOJ-SSDOTTSWSA-N
SMILES: [N+H3]C[C@H](CC(C)C)CC(=O)[O-]

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Safety

WGK Germany: WGK 3
HS Code: 2922493800
Storage Class: 11 - Combustible Solids
Hazard Classifications: Repr. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR8629
Product name: Pregabalin Related Compound A
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 50 mg
Price: $757
Updated: 2026/03/19

Sigma-Aldrich

Product number: PHR8629
Product name: Pregabalin Related Compound A
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 1 unit
Price: $700
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FP27138
Product name: (R)-Pregabalin
Packaging: 10mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP27138
Product name: (R)-Pregabalin
Packaging: 25mg
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP27138
Product name: (R)-Pregabalin
Packaging: 50mg
Price: $300
Updated: 2021/12/16

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Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

(R)-Pregabalin is a GABA analogue used as an anticonvulsant, Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia (less potent than the S-Enantiomer).

Synthesis

Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- was synthesized by the resolution of racemic amide with (S)-1-phenylethylamine in chloroform and ethanol followed by Hofmann reaction^[1].

References

[1] Sripathi, S., Somesetti, N. R., Veeramalla, R., Challa, N. R., Peddi, S., Karnati, V. R. (2010). Synthesis and characterization of impurities of an anticonvulsant drug, Pregabalin. Arkivoc, 2010 1. https://doi.org/10.3998/ARK.5550190.0011.A22

Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- Preparation Products And Raw materials

Raw materials

Preparation Products

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Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- Suppliers

Canada 1 China 92 Germany 1 India 5 United Kingdom 1 United States 5 Global 105

J & K SCIENTIFIC LTD.

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View Lastest Price from Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- 148553-51-9
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2020-04-27

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: (R)-Pregabalin 148553-51-9
Price: US $28.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1 ton
Release date: 2021-12-10

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: (R)-Pregabalin 148553-51-9
Price: US $11.36/KG
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 3tons
Release date: 2021-12-23

148553-51-9, Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)-Related Search:

(S)-Pregabalin Methyl Ester 5,6-Dehydropregabalin Pregabalin Impurity 4 3-isobutylglutaric acid (3S)-3-(N-Methylaminomethyl)-5-methylhexanoic Acid 3-Cyano-5-methylhexanoic Acid Pregabalin Impurity 28 Pregabalin 3-(Aminomethyl)-5-methylhexanoic acid 4-Isobutyl-2-pyrrolidinone Pregabalin Impurity 49 Pregabalin Impurity PD0224377 Isovaleraldehyde 4,9-diisobutyl-1,6-diazecane-2,7-dione 3-((methoxycarbonyl)methyl)-5-methylhexanoic acid 2,4-Dicyano-3-(2-Methylpropyl)-pentanediaMide 2-Hexenamide, 2-cyano-5-methyl- PD 312236

Pregabalin Related Compound A Minimum Pack

EOS-60963

Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)-

(R)-3-(AMinoMethyl)-5-Methylhexanoic acid

ent-Pregabalin

PD 144550

Pregabalin IMpurity V

Pregabalin R-Isomer

Pregabalin EP impurity B

Pregabalin impurity 2/Pregabalin EP Impurity B/(R)-Pregabalin/(R)-3-(aminomethyl)-5-methylhexanoic acid

Pregabalin EP Impurity B ((R)-Pregabalin)

Pregabalin USP Related Compound A

Pregablin Impurity R-pregablin(isomer)

Pregablin R-isomer(Other isomer)

PGL-R-isomer(IMP)

Pregaballin R-Isomer

Pregabalin EP Impurity B/ Pregabalin Related Compound A (Pregabalin (R)-Isomer)

(R)-PregabalinQ: What is (R)-Pregabalin Q: What is the CAS Number of (R)-Pregabalin Q: What is the storage condition of (R)-Pregabalin Q: What are the applications of (R)-Pregabalin

Pregabalin Related Compound A (1559629)

(R)-Isomer of Pregabalin

Pregabalin (R enantiomer)

Pregabalin EP Impurity B USP Pregabalin Related Compound A

Noradrenaline Impurity 38

148553-51-9

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