Iodomethylboronic acid, pinacol ester
- Product Name
- Iodomethylboronic acid, pinacol ester
- CAS No.
- 70557-99-2
- Chemical Name
- Iodomethylboronic acid, pinacol ester
- Synonyms
- 2-(Iodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;Iodomethylboronic acid, pinacol ester;Iodomethylboronic acid, pinacol ester 98%;1,3,2-Dioxaborolane, 2-(iodoMethyl)-4,4,5,5-tetraMethyl-
- CBNumber
- CB02522373
- Molecular Formula
- C7H14BIO2
- Formula Weight
- 267.9
- MOL File
- 70557-99-2.mol
Iodomethylboronic acid, pinacol ester Property
- Boiling point:
- 64-65 °C(Press: 0.2 Torr)
- Density
- 1.47±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- form
- Chloroform, Dichloromethane
- Appearance
- Light yellow to brown Liquid
- InChIKey
- UBNNPAYFVZFWPE-UHFFFAOYSA-N
Safety
- HS Code
- 2931900090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- I1278
- Product name
- 2-(Iodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Purity
- min. 95.0 %
- Packaging
- 1G
- Price
- $74
- Updated
- 2025/07/31
- Product number
- I1278
- Product name
- 2-(Iodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Purity
- min. 95.0 %
- Packaging
- 5G
- Price
- $222
- Updated
- 2025/07/31
- Product number
- I709560
- Product name
- 2-Iodomethyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Packaging
- 500mg
- Price
- $1260
- Updated
- 2021/12/16
- Product number
- 59193
- Product name
- 2-Iodomethyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Packaging
- 500mg
- Price
- $2200
- Updated
- 2021/12/16
- Product number
- CS-W005567
- Product name
- 2-(Iodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Purity
- 99.44%
- Packaging
- 25g
- Price
- $130
- Updated
- 2021/12/16
Iodomethylboronic acid, pinacol ester Chemical Properties,Usage,Production
Chemical Properties
Chloroform, Dichloromethane
Uses
Used in the preparation of Taspase1 inhibitors and α-methylene-γ-butyrolactones. α-Methylene-γ-butyrolactones have the ability to suppress growth in pancreatic carcinoma cells.
Uses
Iodomethylboronic acid pinacol esterUsed is in the preparation of Taspase1 inhibitors and α-methylene-γ-butyrolactones. α-Methylene-γ-butyrolactones have the ability to suppress growth in pancreatic carcinoma cells.
Synthesis
166330-03-6
70557-99-2
The general procedure for the synthesis of iodomethylboronic acid pinacol ester from bromomethylboronic acid pinacol ester is as follows:[Example 22] Synthesis of 2-(iodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane. 2-(Bromomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (2.0 g, 8.3 mmol) was mixed with acetone (17 ml), sodium iodide (1.9 g, 13 mmol) was added, and the reaction mixture was stirred for 2 hours at room temperature. After completion of the reaction, the insoluble impurities were removed by filtration and the filtrate was concentrated under reduced pressure to remove the solvent. Hexane was added to the residue and filtered to remove insoluble matter. Finally, the solvent was evaporated under reduced pressure to afford the target product pinacol ester of iodomethylboronic acid (2.2 g, 97% yield). The product was characterized by 1H-NMR (CDCl3): δ 1.29 (12H, s), 2.59 (2H, s).
References
[1] Patent: EP2062901, 2009, A1. Location in patent: Page/Page column 21-22
Iodomethylboronic acid, pinacol ester Preparation Products And Raw materials
Raw materials
Preparation Products
Iodomethylboronic acid, pinacol ester Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 021-54824098, 021-37212705 021-37212706, 13391256916
- Fax
- 021-54824069
- sales@chemzq.com
- Country
- China
- ProdList
- 570
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- 0519-81096292 15312577869
- chemscaler@yahoo.com.cn
- Country
- China
- ProdList
- 311
- Advantage
- 60
- Tel
- 0411-62313318 13942603642
- Fax
- 0411-87549748
- info@allychem.com
- Country
- China
- ProdList
- 1028
- Advantage
- 65
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
View Lastest Price from Iodomethylboronic acid, pinacol ester manufacturers
- Product
- Iodomethylboronic acid, pinacol ester 70557-99-2
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-07-02
- Product
- Iodomethylboronic acid, pinacol ester 70557-99-2
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100g , 1kg, 5kg , 50kg
- Release date
- 2020-01-07