DOTA-mono-NHS tris(t-Bu ester)
- Product Name
- DOTA-mono-NHS tris(t-Bu ester)
- CAS No.
- 819869-77-7
- Chemical Name
- DOTA-mono-NHS tris(t-Bu ester)
- Synonyms
- DOTA-(COOt-Bu)3-NHS;DOTA-tris-tBu-ester NHS;DOTA tris(tBu)ester NHS ester;DOTA-Mono-NHS-tris(t-Bu ester);DOTA-mono-NHS-tris(t-Butyl ester);DOTA-mono-NHS-tris(t-Bu ester)(B-270);2-[1, 4, 7, 10-Tetraazacyclododecane-4, 7, 10-tris(t-butyl acetate)I-pentanedioic acid-1-t-butyl ester;1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 4,7,10-tris(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester;Tri-tert-butyl 2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate;Tri-tert-butyl 2,2'',2''''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
- CBNumber
- CB02561015
- Molecular Formula
- C32H55N5O10
- Formula Weight
- 669.81
- MOL File
- 819869-77-7.mol
DOTA-mono-NHS tris(t-Bu ester) Property
- Boiling point:
- 686.8±65.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- storage temp.
- -20°C, protect from light
- solubility
- DMSO, DMF, acetonitrile
- pka
- 5.49±0.20(Predicted)
- form
- Solid
- color
- White to off-white
- Appearance
- white solid
- InChIKey
- XIICJKXKEDCZEE-UHFFFAOYSA-N
- SMILES
- N1(CC(ON2C(=O)CCC2=O)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CC1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 182428
- Product name
- [4,7-Bis-tert-butoxycarbonylmethyl-10-(2,5-dioxopyrrolidin-1-yloxycarbonylmethyl)-1,4,7,10-tetraazacyclododec-1-yl]-acetic acid tert-butyl ester
- Purity
- 95%
- Packaging
- 1g
- Price
- $1320
- Updated
- 2021/12/16
- Product number
- A562779
- Product name
- Tri-tert-butyl2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
- Purity
- 95%
- Packaging
- 50mg
- Price
- $182
- Updated
- 2021/12/16
- Product number
- A562779
- Product name
- Tri-tert-butyl2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
- Purity
- 95%
- Packaging
- 100mg
- Price
- $236
- Updated
- 2021/12/16
- Product number
- A562779
- Product name
- Tri-tert-butyl2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $351
- Updated
- 2021/12/16
- Product number
- 6571467
- Product name
- [4,7-Bis-tert-butoxycarbonylmethyl-10-(2,5-dioxo-pyrrolidin-1-yloxycarbonylmethyl)-1,4,7,10-tetraaza-cyclododec-1-yl]-aceticacidtert-butylester
- Purity
- 95%
- Packaging
- 1g
- Price
- $700
- Updated
- 2021/12/16
DOTA-mono-NHS tris(t-Bu ester) Chemical Properties,Usage,Production
Description
DOTA (dodecane tetraacetic acid, also known as tetraxetan) is a complexing agent, especially for lanthanide ions. DOTA-NHS ester is a bifunctional linker containing chelating and N-hydroxysuccinimide (NHS) ester groups for conjugation with amine-containing biomolecules.
DOTA-NHS ester can be used to label radiotherapeutic agents or imaging probes and detect labeled tumors with PET, SPECT, and CT methods.
Uses
DOTA-tris(tBu)ester NHS ester is a derivative of DOTA for the labeling of peptides and antibodies[1].
References
[1] Wngler C, et, al. Improved syntheses and applicability of different DOTA building blocks for multiply derivatized scaffolds. Bioorg Med Chem. 2008 Mar 1; 16(5): 2606-16. DOI:10.1016/j.bmc.2007.11.044
DOTA-mono-NHS tris(t-Bu ester) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from DOTA-mono-NHS tris(t-Bu ester) manufacturers
- Product
- DOTA-(COOt-Bu)3-NHS 819869-77-7
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >95.00%
- Supply Ability
- 500mg
- Release date
- 2024-04-01
- Product
- DOTA-tris-tBu-esterNHS 819869-77-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.5%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14