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DOTA-mono-NHS tris(t-Bu ester)

Product Name
DOTA-mono-NHS tris(t-Bu ester)
CAS No.
819869-77-7
Chemical Name
DOTA-mono-NHS tris(t-Bu ester)
Synonyms
DOTA-(COOt-Bu)3-NHS;DOTA-tris-tBu-ester NHS;DOTA tris(tBu)ester NHS ester;DOTA-Mono-NHS-tris(t-Bu ester);DOTA-mono-NHS-tris(t-Butyl ester);DOTA-mono-NHS-tris(t-Bu ester)(B-270);2-[1, 4, 7, 10-Tetraazacyclododecane-4, 7, 10-tris(t-butyl acetate)I-pentanedioic acid-1-t-butyl ester;1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 4,7,10-tris(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester;Tri-tert-butyl 2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate;Tri-tert-butyl 2,2'',2''''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
CBNumber
CB02561015
Molecular Formula
C32H55N5O10
Formula Weight
669.81
MOL File
819869-77-7.mol
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DOTA-mono-NHS tris(t-Bu ester) Property

Boiling point:
686.8±65.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
storage temp. 
-20°C, protect from light
solubility 
DMSO, DMF, acetonitrile
pka
5.49±0.20(Predicted)
form 
Solid
color 
White to off-white
Appearance
white solid
InChIKey
XIICJKXKEDCZEE-UHFFFAOYSA-N
SMILES
N1(CC(ON2C(=O)CCC2=O)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CC1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
182428
Product name
[4,7-Bis-tert-butoxycarbonylmethyl-10-(2,5-dioxopyrrolidin-1-yloxycarbonylmethyl)-1,4,7,10-tetraazacyclododec-1-yl]-acetic acid tert-butyl ester
Purity
95%
Packaging
1g
Price
$1320
Updated
2021/12/16
Ambeed
Product number
A562779
Product name
Tri-tert-butyl2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
Purity
95%
Packaging
50mg
Price
$182
Updated
2021/12/16
Ambeed
Product number
A562779
Product name
Tri-tert-butyl2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
Purity
95%
Packaging
100mg
Price
$236
Updated
2021/12/16
Ambeed
Product number
A562779
Product name
Tri-tert-butyl2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
Purity
95%
Packaging
250mg
Price
$351
Updated
2021/12/16
A1 Biochem Labs
Product number
6571467
Product name
[4,7-Bis-tert-butoxycarbonylmethyl-10-(2,5-dioxo-pyrrolidin-1-yloxycarbonylmethyl)-1,4,7,10-tetraaza-cyclododec-1-yl]-aceticacidtert-butylester
Purity
95%
Packaging
1g
Price
$700
Updated
2021/12/16
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DOTA-mono-NHS tris(t-Bu ester) Chemical Properties,Usage,Production

Description

DOTA (dodecane tetraacetic acid, also known as tetraxetan) is a complexing agent, especially for lanthanide ions. DOTA-NHS ester is a bifunctional linker containing chelating and N-hydroxysuccinimide (NHS) ester groups for conjugation with amine-containing biomolecules.


DOTA-NHS ester can be used to label radiotherapeutic agents or imaging probes and detect labeled tumors with PET, SPECT, and CT methods.

Uses

DOTA-tris(tBu)ester NHS ester is a derivative of DOTA for the labeling of peptides and antibodies[1].

References

[1] Wngler C, et, al. Improved syntheses and applicability of different DOTA building blocks for multiply derivatized scaffolds. Bioorg Med Chem. 2008 Mar 1; 16(5): 2606-16. DOI:10.1016/j.bmc.2007.11.044

DOTA-mono-NHS tris(t-Bu ester) Preparation Products And Raw materials

Raw materials

Preparation Products

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DOTA-mono-NHS tris(t-Bu ester) Suppliers

Shanghai Minhan Pharmaceutical Technology Co., Ltd.
Tel
17612188245
Fax
QQ 2816925681
Email
2816925681@qq.com
Country
China
ProdList
9857
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58
Nanchang Tianzhen Biotechnology Co., Ltd
Tel
13758194781 13173652190
Email
522013271@qq.com
Country
China
ProdList
2444
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58
Grice Rand (Tianjin) Pharmaceutical Co., Ltd.
Tel
022-83705301 13752403750
Fax
022-83705301
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2966024760@qq.com
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China
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Xi'an Kaixin Biotechnology Co., Ltd
Tel
029-68881181 13619217766
Fax
029-68881181
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3495811982@qq.com
Country
China
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58
Henan Mengtai Pharmaceutical Technology Co., Ltd
Tel
17634413542
Email
1959525201@qq.com
Country
China
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9999
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58
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
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60
Hangzhou Sage Chemical Co., Ltd.
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+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
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Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
50266790 18317173152
Fax
QQ3382968513
Email
Hailey@shsendpharm.com
Country
China
ProdList
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55
Quzhou AMK BioTech Co., Ltd
Tel
0570-3081766 18357083060
Fax
0570-3072337
Email
sales@qzamkbio.com
Country
China
ProdList
1154
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Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9433
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View Lastest Price from DOTA-mono-NHS tris(t-Bu ester) manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
DOTA-(COOt-Bu)3-NHS 819869-77-7
Price
US $0.00/mg
Min. Order
500mg
Purity
>95.00%
Supply Ability
500mg
Release date
2024-04-01
Honest Joy Holdings Limited
Product
DOTA-tris-tBu-esterNHS 819869-77-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98.5%
Supply Ability
100 tons
Release date
2022-01-14

819869-77-7, DOTA-mono-NHS tris(t-Bu ester)Related Search:


  • DOTA-mono-NHS-tris(t-Bu ester)(B-270)
  • DOTA-Mono-NHS-tris(t-Bu ester)
  • 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-, tris(1,1-diMethylethyl) ester
  • DOTA-tris-tBu-ester NHS
  • 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 4,7,10-tris(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester
  • DOTA tris(tBu)ester NHS ester
  • 2-[1, 4, 7, 10-Tetraazacyclododecane-4, 7, 10-tris(t-butyl acetate)I-pentanedioic acid-1-t-butyl ester
  • DOTA-mono-NHS-tris(t-Butyl ester)
  • DOTA-(COOt-Bu)3-NHS
  • Tri-tert-butyl 2,2'',2''''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
  • Tri-tert-butyl 2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
  • tert-butyl 2-{4,7-bis[2-(tert-butoxy)-2-oxoethyl]-10-{2-[(2,5-dioxopyrrolidin-1-yl)oxy]-2-oxoethyl}-1,4,7,10-tetraazacyclododecan-1-yl}acetate
  • 2,2',2''-(10-(2-((2,5-dioxypyrolidine-1-yl)oxy)-2-oxyethyl)-1,4,7,10-tetrazacyclodecane-1,4,7-triyl)triacetic acidtritertbutyl ester
  • 819869-77-7
  • C32H55N5O10
  • RDC Linker
  • PDC Linker