Edoxaban Impurity 12 (1R,2R,4S)

Product Name: Edoxaban Impurity 12 (1R,2R,4S)
CAS No.: 500572-10-1
Chemical Name: Edoxaban Impurity 12 (1R,2R,4S)
Synonyms: HPLC>=95%;Edoxaban-16;1-epi-Edoxaban;Enantiomer(RRS);Edoxaban Isomer (RRS);Edoxaban (RRS)-Isomer;Edoxaban iMpurities 16;Yidu Saban Impurity RRS;Edoxaban (1R,2R,4S) Isomer;Edoxaban RRS Isomer Impurity
CBNumber: CB02570334
Molecular Formula: C24H30ClN7O4S
Formula Weight: 548.06
MOL File: 500572-10-1.mol

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Edoxaban Impurity 12 (1R,2R,4S) Property

Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: Store at 0-8 °C
pka: 9.46±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: E555555
Product name: 1-epi-Edoxaban
Packaging: 10mg
Price: $16225
Updated: 2021/12/16

TRC

Product number: E555555
Product name: 1-epi-Edoxaban
Packaging: 25mg
Price: $21835
Updated: 2021/12/16

Alichem

Product number: 500572101
Product name: N1-(5-Chloropyridin-2-yl)-N2-((1R,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
Packaging: 5mg
Price: $907.92
Updated: 2021/12/16

Crysdot

Product number: CD11115646
Product name: N1-(5-Chloropyridin-2-yl)-N2-((1R,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
Purity: 95+%
Packaging: 10mg
Price: $1398
Updated: 2021/12/16

Alichem

Product number: 500572101
Product name: N1-(5-Chloropyridin-2-yl)-N2-((1R,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
Packaging: 10mg
Price: $1481.88
Updated: 2021/12/16

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Edoxaban Impurity 12 (1R,2R,4S) Chemical Properties,Usage,Production

Uses

1-epi-Edoxaban is an impurity of Edoxaban (E555520) which is an anticoagulant drug which acts as a direct factor Xa inhibitor.

Edoxaban Impurity 12 (1R,2R,4S) Preparation Products And Raw materials

Raw materials

Preparation Products

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Edoxaban Impurity 12 (1R,2R,4S) Suppliers

China 53 India 4 United States 3 Global 60

Daicel Chiral Technologies (China)CO.,LTD

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500572-10-1, Edoxaban Impurity 12 (1R,2R,4S)Related Search:

Rivaroxaban edoxaban EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- EthanediaMide iMpurity D 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2S,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- 2-BroMo-5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine (1S,3R,4S)-4-(2-((5-chloropyridin- 2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylic acid tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate 2-Amino-5-chloropyridine Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- EthanediaMide, N1-(5-chlo... (1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- carbamic acid, n-[(1r,2r,5s)-5-[(dimethylamino)carbonyl]-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester (1R,3S,4R)-3-Amino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester hydrochloride Edoxaban Impurity 37

EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2R,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]-

N1-(5-chloropyridin-2-yl)-N2-((1R,2R,4S)-4-(diMethylcarbaMoyl)-2-(5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxaMido)cyclohexyl)oxalaMide

Enantiomer(RRS)

Edoxaban impurity 7/Edoxaban RRS Isomer

Edoxaban impurity 7/1-epi-Edoxaban/Edoxaban RRS Isomer/N1-(5-chloropyridin-2-yl)-N2-((1R,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide

Edoxaban iMpurities 16

Edoxaban-16

(5-chloropyridin-2-yl)-N2-((1R,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide

N1-(5-chloro-2-pyridinyl)-N2-[(1R,2R,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- EthanediaMide

Edoxaban Isomer (RRS)

N1-(5-chloropyridin-2-yl)-N2-((1R,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide

Edoxaban (RRS)-Isomer

HPLC>=95%

Edoxaban RRS Isomer Impurity

1-epi-Edoxaban

N1-(5-chloropyridin-2-yl)-N2-((1R,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamid

EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2R,4S)-4-[(...

Edoxaban (RRS)-Isomer Tosylate

Yidu Saban Impurity RRS

N-(5-chloro-2-pyridyl)-N'-[(1R,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide

Edoxaban (1R,2R,4S) Isomer

500572-10-1