ChemicalBook > CAS DataBase List > METHYL 4-FORMYL-3-HYDROXYBENZOATE

METHYL 4-FORMYL-3-HYDROXYBENZOATE

Product Name: METHYL 4-FORMYL-3-HYDROXYBENZOATE
CAS No.: 24589-98-8
Chemical Name: METHYL 4-FORMYL-3-HYDROXYBENZOATE
Synonyms: ethyl 4-forMyl-3-hydroxybenzoate;4-CarboMethoxysalicylaldehyde;methyl 4-formyl-3-hydoxybenzoate;METHYL 4-FORMYL-3-HYDROXYBENZOATE;Benzoic acid, 4-formyl-3-hydroxy-, methyl ester
CBNumber: CB02615936
Molecular Formula: C9H8O4
Formula Weight: 180.16
MOL File: 24589-98-8.mol

Less

METHYL 4-FORMYL-3-HYDROXYBENZOATE Property

Melting point:: 135-135.5 °C(Solv: ethyl acetate (141-78-6))
Boiling point:: 324.1±27.0 °C(Predicted)
Density: 1.310±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 7.36±0.10(Predicted)
Appearance: Off-white to yellow Solid
InChI: InChI=1S/C9H8O4/c1-13-9(12)6-2-3-7(5-10)8(11)4-6/h2-5,11H,1H3
InChIKey: OMCTZIDLDSYPOA-UHFFFAOYSA-N
SMILES: C(OC)(=O)C1=CC=C(C=O)C(O)=C1

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

TRC

Product number: C177725
Product name: 4-Carbomethoxysalicylaldehyde
Packaging: 1g
Price: $1320
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 55403
Product name: 4-Carbomethoxysalicylaldehyde
Packaging: 250mg
Price: $290
Updated: 2021/12/16

AK Scientific

Product number: 6190BB
Product name: Methyl4-formyl-3-hydroxybenzoate
Packaging: 5g
Price: $860
Updated: 2021/12/16

Alichem

Product number: 24589988
Product name: Methyl3-hydroxy-4-formylbenzoate
Packaging: 500mg
Price: $863.9
Updated: 2021/12/16

Ambeed

Product number: A116776
Product name: Methyl4-formyl-3-hydroxybenzoate
Purity: 95%
Packaging: 10g
Price: $965
Updated: 2021/12/16

Less

METHYL 4-FORMYL-3-HYDROXYBENZOATE Chemical Properties,Usage,Production

Uses

4-Carbomethoxysalicylaldehyde is used in the preparation of α-glucosidase inhibitors. Also used in the preparation of β-lactamase substrates.

Synthesis

67-56-1

619-12-5

24589-98-8

Step 1: Synthesis of methyl 4-formyl-3-hydroxybenzoate (239) 4-Formyl-3-hydroxybenzoic acid (1.2 g, 7.22 mmol) was dissolved in methanol (10 ml). Sulfoxide chloride (1.054 ml, 14.45 mmol) was added slowly and the reaction mixture was stirred at 60 °C for 3 h to ensure complete reaction. After completion of the reaction, the reaction mixture was concentrated under reduced pressure. The crude product was ground with hexane and subsequently filtered to afford methyl 4-formyl-3-hydroxybenzoate (1.3 g, 7.22 mmol, 100% yield) as a white solid. Mass spectrometric analysis (MS/ESI+) showed the molecular ion peak m/z 181.04 [MH]+.

References

[1] Patent: US2014/155391, 2014, A1. Location in patent: Paragraph 0617; 0618
[2] Patent: US2012/245144, 2012, A1. Location in patent: Page/Page column 105
[3] Journal of the American Chemical Society, 1955, vol. 77, p. 973,979
[4] Journal of Medicinal Chemistry, 1969, vol. 12, # 3, p. 420 - 424
[5] Bioorganic and Medicinal Chemistry, 2001, vol. 9, # 5, p. 1175 - 1183

METHYL 4-FORMYL-3-HYDROXYBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

METHYL 4-FORMYL-3-HYDROXYBENZOATE Suppliers

China 49 India 1 United States 1 Global 51

TR Pharma & Tech Co., Ltd.

Tel: 0531-88633905 15863156350
Fax: 15863156350
Email: jntryy@hotmail.com
Country: China
ProdList: 51
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Beijing Eternalchem Co,. Ltd.

Tel: 010-59484199 18611897322
Email: sales@eternalchem.com
Country: China
ProdList: 4383
Advantage: 60

Shanghai Synthfine Chemical Co.,Ltd

Tel: 15921303235
Fax: QQ489466966
Email: sales@synthfine.com
Country: China
ProdList: 1041
Advantage: 58

Shanghai Raise Chemical Technology Co.,Ltd

Tel: 15026594951
Fax: 0556-5030632
Email: rs@raise-chem.com
Country: China
ProdList: 4454
Advantage: 55

Shanghai Dano Pharmaceutical Co., LTD(China)

Tel: 0592-6266840 15750707980
Email: sales@chemsdano.com
Country: China
ProdList: 357
Advantage: 57

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai ChuangYan Chemical Technology Co., Ltd.

Tel: 021-11111111 11111111111
Fax: qq:546919421
Email: 546919421@qq.com
Country: China
ProdList: 3526
Advantage: 55

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai silk sail pharmaceutical technology co., LTD

Tel: 18916696128
Email: service@snowpharm.com
Country: China
ProdList: 1369
Advantage: 58

Shanghai Changer Pharmaceutical Technology Co. Ltd.

Tel: 15921595598
Email: qd.yu@pharmachanger.com
Country: China
ProdList: 468
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Shanghai zhigan biotechnology co., LTD

Tel
Email: zhiqianbio@126.com
Country: China
ProdList: 19778
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

Blocksynth Pharmaceutical Technology Co.,Ltd

Tel: 0086-19817745290; +8619817745290
Email: bd@blocksynth.com
Country: China
ProdList: 5661
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

Xiamen Shindano Biotechnology Co.,ltd

Tel: 0592-6266840 15750707980
Email: sales@chemsdano.com
Country: China
ProdList: 291
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9948
Advantage: 58

Shanghai Hongju Pharmaceutical Technology Co., LTD

Tel: 18001895509
Fax: QQ2934193566;
Email: 986383309@qq.com
Country: China
ProdList: 2680
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Hubei Co-prosperity Medicine Technonlogy Co., Ltd

Tel: 2383948258 19172820304
Email: 2383948258@qq.com
Country: China
ProdList: 12987
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Wuhan HSN Pharmaresearch CO., LTD.

Tel: 027-81525288 18086100502
Fax: 027-86589137
Email: linwell@126.com
Country: China
ProdList: 233
Advantage: 50

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Jieshikai Biotechnology Co. , Ltd.

Tel: 021-57520305 13795461237
Email: zhuruyan@jskchem.com
Country: China
ProdList: 49234
Advantage: 58

Tianjin Ruide Famo Technology Co., Ltd

Tel: 13821803402
Email: RD_PHARM@163.com
Country: China
ProdList: 842
Advantage: 58

Ningbo Zhenyue Pharmaceutical Technology Co., Ltd

Tel: 19817745290
Email: bd@blocksynth.com
Country: China
ProdList: 5870
Advantage: 58

Shaoyuan Technology (Shanghai) Co., Ltd.

Tel: 021-50795510 4000665055
Email: sy-c5@accelachem.com
Country: China
ProdList: 10000
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 19355912709
Email: 690231469@qq.com
Country: China
ProdList: 7593
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: 18143011203
Email: ET-market@chemextension.com
Country: China
ProdList: 32048
Advantage: 58

BEIJINGYIWANJINGRUI

Tel: 15866847540
Email: dengyt2000@163.com
Country: China
ProdList: 4100
Advantage: 58

Shanghai Hansi Chemical Industry Co., Ltd.

Tel: 17717618050
Email: zllg@gh-reagent.com
Country: China
ProdList: 10420
Advantage: 58

Shandong Dongde New Materials Co., Ltd

Tel: 15666167041
Email: 15666167041@163.com
Country: China
ProdList: 2999
Advantage: 58

Shanghai Ken chemical Technology Co.,ltd

Tel: 02152215958
Email: 47697177@qq.com
Country: China
ProdList: 10011
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Compound Net Biotechnology Inc.

Tel: +8615303909093
Email: sales@compound-net.com
Country: China
ProdList: 2914
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

Aromsyn Co., Ltd.

Tel: +86-0571-85585865 +8613336024896
Email: CB@aromsyn.com
Country: China
ProdList: 19183
Advantage: 58

24589-98-8, METHYL 4-FORMYL-3-HYDROXYBENZOATERelated Search:

METHYL 5-CYANO-2-METHOXYBENZOATE Methyl 4-broMo-2-chloro-5-fluorobenzoate Methyl 5-bromomethyl-2-nitro-benzoate Methyl 4-(bromomethyl)-2,5-dichlorobenzoate methyl 5-bromo-2-methoxybenzoate methyl 5-chloro-2-formylbenzoate methyl 5-formyl-2-nitrobenzoate Methyl 5-broMo-2-fluoro-3-nitrobenzoate 5-BroMo-2,4-difluoro-benzoic acid Methyl ester Methyl 4-hydroxy-2-methylbenzoate METHYL 5-BROMO-2-IODOBENZOATE Methyl 5-nitro-2-(trifluoromethyl)benzoate Methyl 5-aMino-2-iodobenzoate methyl 5-amino-2-(trifluoromethyl)benzoate methyl 4-bromo-2-formylbenzoate Methyl 4-bromo-2,6-dichlorobenzoate Methyl 4-formyl-3-methylbenzoate RARECHEM AL BF 0506

METHYL 4-FORMYL-3-HYDROXYBENZOATE

ethyl 4-forMyl-3-hydroxybenzoate

4-CarboMethoxysalicylaldehyde

methyl 4-formyl-3-hydoxybenzoate

Benzoic acid, 4-formyl-3-hydroxy-, methyl ester

24589-98-8

Aromatics, Miscellaneous Reagents