(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine

Product Name: (2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine
CAS No.: 147116-67-4
Chemical Name: (2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine
Synonyms: CJ-11972);Maropitan;Maropitant;Horse's temple;Maropitant base;Maropitant (CJ11,972;Pafolacianine Impurity 5;Maropitant, 10 mM in DMSO;Maropitant intermediate 6;(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine
CBNumber: CB02622781
Molecular Formula: C32H40N2O
Formula Weight: 468.67
MOL File: 147116-67-4.mol

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(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Property

Boiling point:: 572.6±50.0 °C(Predicted)
Density: 1.11±0.1 g/cm3(Predicted)
vapor pressure: 0-0Pa at 20-25℃
storage temp.: Store at -20°C
solubility: DMSO : 33.33 mg/mL (71.12 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form: Solid:particulate/powder
pka: 9.99±0.70(Predicted)
color: Off-white to yellow
InChIKey: OMPCVMLFFSQFIX-CONSDPRKSA-N
SMILES: N12CCC(CC1)[C@H](NCC1=CC(C(C)(C)C)=CC=C1OC)[C@@H]2C(C1=CC=CC=C1)C1=CC=CC=C1
LogP: 3.1-7.2 at pH2-7.5
CAS DataBase Reference: 147116-67-4

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids
Hazard Classifications: Aquatic Acute 1
Aquatic Chronic 1
Skin Sens. 1
STOT RE 2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P314Get medical advice/attention if you feel unwell.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: M3606
Product name: Maropitant
Packaging: 10MG
Price: $143
Updated: 2026/03/19

ChemScene

Product number: CS-1065
Product name: Maropitant
Purity: 99.79%
Packaging: 2mg
Price: $180
Updated: 2021/12/16

AK Scientific

Product number: 2790CB
Product name: Maropitant
Packaging: 2mg
Price: $270
Updated: 2021/12/16

ChemScene

Product number: CS-1065
Product name: Maropitant
Purity: 99.79%
Packaging: 5mg
Price: $288
Updated: 2021/12/16

AK Scientific

Product number: 2790CB
Product name: Maropitant
Packaging: 5mg
Price: $432
Updated: 2021/12/16

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(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Chemical Properties,Usage,Production

Uses

Maropitant is a neurokinin type 1 (NK-1) receptor antagonist. Recent studies show that Maropitant decreased the anesthetic requirements during visceral stimulation of the ovary and ovarian ligament in dogs.

Biological Activity

Maropitant is a neurokinin-1 receptor (NK-1R) antagonist with in vivo antiemetic efficacy.

in vivo

Treatment with 1 mg/kg Maropitant citrate, significantly reduces the size of ulcerative dermatitis (UD) lesions in mice. Intravenous Maropitant decreases MAC by 16%. In contrast, epidural administration of either saline or Maropitant does not change the MAC (2.17% and 1.92 %, respectively).

IC 50

NK1

(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Suppliers

China 118 India 1 United States 8 Global 127

Tianjin Maitian Technology Co., Ltd

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Chemvon Biotechnology Co., Ltd

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ZHIWE CHEMTECH CO LTD

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View Lastest Price from (2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine manufacturers

HR Biotechnology Co.,Ltd

Product: Maropitant 147116-67-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 200000
Release date: 2023-10-25

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine 147116-67-4
Price: US $9.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-12

XI'AN TIANGUANGYUAN BIOTECH CO., LTD.

Product: Maropitant 147116-67-4
Price: US $10.00/g/Bag
Min. Order: 1g/Bag
Purity: 99%
Supply Ability: 2500g/month
Release date: 2023-06-14

147116-67-4, (2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMineRelated Search:

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(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine

(2S-cis)-N-[[5-(1,1-DiMethylethyl)-2-Methoxyphenyl]Methyl]-2-(diphenylMethyl)-1-azabicyclo[2.2.2]octan-3-aMine

Maropitant

(2S,3S)-2-(Diphenylmethyl)-N-[2-methoxy-5-(2-methyl-2-propanyl)benzyl]quinuclidin-3-amine

1-Azabicyclo[2.2.2]octan-3-amine, N-[[5-(1,1-dimethylethyl)-2-methoxyphenyl]methyl]-2-(diphenylmethyl)-, (2S,3S)-

CJ-11972)

Maropitant (CJ11,972

Maropitant-13C-d3Q: What is Maropitant-13C-d3 Q: What is the CAS Number of Maropitant-13C-d3

Maropitant base

Horse's temple

Maropitan

(2S,3S)-2-benzhydryl-N-[(5-tert-butyl-2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine

Maropitant intermediate 6

Pafolacianine Impurity 5

(2S,3S)-2-benzhydryl-N-[(5-tert-butyl-2-methoxy-phenyl)methyl]quinuclidin-3-amine

Maropitant, 10 mM in DMSO

147116-67-4

API

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals