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AKT Kinase Inhibitor

Product Name
AKT Kinase Inhibitor
CAS No.
842148-40-7
Chemical Name
AKT Kinase Inhibitor
Synonyms
3-[2-(4-amino-1;5-c]pyridin-4-yl]-;AKT Kinase Inhibito;AKT Kinase Inhibitor;AKT Kinase Inhibitor USP/EP/BP;AKT Kinase Inhibitor, 10 mM in DMSO;5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4;3-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-propyn-1-ol;2-Propyn-1-ol, 3-[2-(4-aMino-1,2,5-oxadiazol-3-yl)-7-(3-aMinopropoxy)-1-ethyl-1H-iMidazo[4,5-c]pyridin-4-yl]-;AKT Kinase Inhibitor (2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-)
CBNumber
CB02624073
Molecular Formula
C16H19N7O3
Formula Weight
357.37
MOL File
842148-40-7.mol
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AKT Kinase Inhibitor Property

Boiling point:
678.8±65.0 °C(Predicted)
Density 
1.50
storage temp. 
Store at -20°C
solubility 
DMSO : 16.67 mg/mL (46.65 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
Powder
pka
12.98±0.10(Predicted)
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0528
Product name
AKTKinaseInhibitor
Purity
98.37%
Packaging
5mg
Price
$420
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0292909
Product name
3-[2-(4-AMINO-1,2,5-OXADIAZOL-3-YL)-7-(3-AMINOPROPOXY)-1-ETHYL-1H-IMIDAZO-[4,5-C]PYRIDIN-4-YL]-2-PROPYN-1-OL
Purity
95.00%
Packaging
5MG
Price
$499.08
Updated
2021/12/16
ChemScene
Product number
CS-0528
Product name
AKTKinaseInhibitor
Purity
98.37%
Packaging
10mg
Price
$720
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611707
Product name
AKT Kinase Inhibitor
Packaging
10mg
Price
$734.4
Updated
2021/12/16
Crysdot
Product number
CD31000662
Product name
AKTKinaseInhibitor
Purity
98+%
Packaging
5mg
Price
$245
Updated
2021/12/16
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AKT Kinase Inhibitor Chemical Properties,Usage,Production

Uses

AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity[1].

Biological Activity

AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity.

in vivo

Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus.

target

Akt

References

[1] Saverio Alberti, et al. Use of trop-2 as predictive marker of response to anti-tumor therapy based on inhibitors of cd9, akt and molecules of the tetraspanin signalling network. WO2013171777A2.

AKT Kinase Inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from AKT Kinase Inhibitor manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
AKT Kinase Inhibitor 842148-40-7
Price
US $2.00-6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-ton
Release date
2025-07-28

842148-40-7, AKT Kinase InhibitorRelated Search:

AKTI-1/2 6-Mercaptopurine 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol HYDROXYFASUDIL MONOHYDROCHLORIDE Peficitinib hydrobromide

  • AKT Kinase Inhibitor
  • 3-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-propyn-1-ol
  • 2-Propyn-1-ol, 3-[2-(4-aMino-1,2,5-oxadiazol-3-yl)-7-(3-aMinopropoxy)-1-ethyl-1H-iMidazo[4,5-c]pyridin-4-yl]-
  • AKT Kinase Inhibitor (2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-)
  • 3-[2-(4-amino-1
  • 5-c]pyridin-4-yl]-
  • 5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4
  • AKT Kinase Inhibitor USP/EP/BP
  • AKT Kinase Inhibito
  • AKT Kinase Inhibitor, 10 mM in DMSO
  • 842148-40-7