DECYLUBIQUINONE

Product Name: DECYLUBIQUINONE
CAS No.: 55486-00-5
Chemical Name: DECYLUBIQUINONE
Synonyms: DECYLUBIQUINONE;6-decylubiquinone;Decylubiquinone (2,3-Dmdb);2,3-DIMETHOXY-5-METHYL-6-DECYL-1,4-BENZOQUINONE;2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione;2,5-Cyclohexadiene-1,4-dione, 2-decyl-5,6-dimethoxy-3-methyl-
CBNumber: CB0262439
Molecular Formula: C19H30O4
Formula Weight: 322.44
MOL File: 55486-00-5.mol

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DECYLUBIQUINONE Property

Boiling point:: 452.9±45.0 °C(Predicted)
Density: 1.02±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO (up to 10 mg/ml)
form: Neat yellow to orange colored oil.
color: Yellow or orange
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D7911
Product name: Decylubiquinone
Purity: ≥97% (HPLC)
Packaging: 10mg
Price: $122
Updated: 2024/03/01

Sigma-Aldrich

Product number: D7911
Product name: Decylubiquinone
Purity: ≥97% (HPLC)
Packaging: 25mg
Price: $242
Updated: 2024/03/01

Cayman Chemical

Product number: 21027
Product name: Decylubiquinone
Purity: ≥98%
Packaging: 5mg
Price: $35
Updated: 2024/03/01

Cayman Chemical

Product number: 21027
Product name: Decylubiquinone
Purity: ≥98%
Packaging: 10mg
Price: $53
Updated: 2024/03/01

Sigma-Aldrich

Product number: D7911
Product name: Decylubiquinone
Purity: ≥97% (HPLC)
Packaging: 100mg
Price: $648
Updated: 2024/03/01

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DECYLUBIQUINONE Chemical Properties,Usage,Production

Description

Decylubiquinone (55486-00-5) inhibits the Ca2+?dependent mitochondrial permeability transition pore (MPTP) without inhibiting respiration.1?Maximum effect on Ca2+?retention capacity of rat liver mitochondria at 100 μM. Inhibits etoposide-induced apoptosis in in L929 cells at 5 μM via inhibition of cytochrome C release.2?Delays rotenone-induced cardiac dysfunction in a zebrafish model of development and cardiovascular function.3?Substrate for various quinone oxidoreductases.4,5

Uses

Decylubiquinone is inhibits the Ca2+-dependent mitochondrial permeability transition pore (MPTP) and also inhibits etoposide-induced apoptosis.

Definition

ChEBI: 6-decylubiquinone is a member of the class of 1,4-benzoquinones that is 2,3-dimethoxybenzoquinone which has been substituted at positions 5 and 6 by decyl and methyl groups. It has a role as a cofactor. It is functionally related to a 6-decylubiquinol.

General Description

Ubiquinone analog.

References

1) Fontaine?et al. (1998),?A Ubiquinone-binding Site Regulates the Mitochondrial Permeability Transition Pore; J. Biol. Chem.,?273?25734 2) Karpinich?et al. (2002),?The course of Etoposide-Induced Apoptosis from Damage to DNA and p53 Activation to Mitochondrial Release of Cytochrome c; J. Biol. Chem.,?277?16547 3) Pinho?et al. (2013)?How mitochondrial dysfunction affects zebrafish development and cardiovascular function: an in vivo model for testing mitochondria-targeted drugs; Br. J. Pharmacol.,?169?1072 4) Kunow?et al.?(1994)?F420H2: quinone oxidoreductase from Archaeoglobus fulgidus. Characterization of a membrane-bound multisubunit complex containing FAD and iron-sulfur clusters; Eur. J. Biochem.,?223?503 5) Zickermann?et al?(1998)?Analysis of the pathogenic human mitochondria mutation ND1/3460 and mutations of strictly conserved residues in it’s vicinity, using the bacterium Paracoccis denitrificans; Biochemistry,?37?11792

DECYLUBIQUINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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DECYLUBIQUINONE Suppliers

China 26 Germany 1 Switzerland 2 United Kingdom 1 United States 9 Global 39

3B Pharmachem (Wuhan) International Co.,Ltd.

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Sigma-Aldrich

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Shanghai Qiao Chemical Science Co., Ltd

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Aikon International Limited

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Shanghai Hongye Biotechnology Co. Ltd

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TargetMol Chemicals Inc.

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MedBioPharmaceutical Technology Inc

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Energy Chemical

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55486-00-5, DECYLUBIQUINONERelated Search:

Probenecid COENZYME Q2 7-CHLORO-5-(2-CHLOROPHENYL)-1,5-DIHYDRO-4,1-BENZOTHIAZEPIN-2(3H)-ONE CITRININ BA, 3NH4 CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE FCCP Mirin METHOXYBENZOQUINONE p-Toluquinone Idebenone PRIMIN 2,3-Dimethoxy-5-methyl-p-benzoquinone 2,3-DIMETHOXY-5,6-DIMETHYL-P-BENZOQUINONE 3-methoxy-2,5-toluquinone 2,3-DIMETHOXY-1,4-BENZOQUINONE DECYLUBIQUINONE 2,3-dimethyl-2,5-cyclohexadiene-1,4 dione

2,3-DIMETHOXY-5-METHYL-6-DECYL-1,4-BENZOQUINONE

6-decylubiquinone

2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione

Decylubiquinone (2,3-Dmdb)

DECYLUBIQUINONE

2,5-Cyclohexadiene-1,4-dione, 2-decyl-5,6-dimethoxy-3-methyl-

55486-00-5

C19H30O4