MACULOSIN

Product Name
MACULOSIN
CAS No.
4549-02-4
Chemical Name
MACULOSIN
Synonyms
A-19C;ML-1532II;MACULOSIN;CYCLO(-PRO-TYR);Antibiotic A-19C;cyclo(L-Pro-L-Tyr);Cyclo(L-Tyr-L-Pro-);MACULOSIN USP/EP/BP;Antibiotic ML-1532II;Cyclo(L-prolinyl-L-tyrosine)
CBNumber
CB0265753
Molecular Formula
C14H16N2O3
Formula Weight
260.29
MOL File
4549-02-4.mol
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MACULOSIN Property

Melting point:
156-159 °C
Boiling point:
581.4±43.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
-15°C
pka
9.92±0.15(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25019
Product name
Maculosin
Purity
≥95%
Packaging
5mg
Price
$105
Updated
2021/03/22
Cayman Chemical
Product number
25019
Product name
Maculosin
Purity
≥95%
Packaging
25mg
Price
$341
Updated
2021/03/22
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MACULOSIN Chemical Properties,Usage,Production

Uses

Cyclo(L-Pro-L-Tyr) (maculosin) is a diketopiperazine formed by the fusion of tyrosine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Pro-L-Tyr) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Pro-L-Tyr) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of cyclo(L-Pro-L-Tyr) is not known, its activity suggests the existence of cross talk among bacterial signalling systems. Cyclo(L-Pro-L-Tyr) was identified as a host-specific toxin produced by Alternaria alternata on spotted knapweed.

Definition

ChEBI: A homodetic cyclic peptide that is a dipeptide composed of L-proline and L-tyrosine joined by peptide linkages.

MACULOSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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MACULOSIN Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452- ;21-61263452-
Fax
86-21-61263399
Email
ymbetter@glbiochem.com;ymbetter@glbiochem.com
Country
China
ProdList
9940
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15424
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-66853366-
Email
sales@chem-strong.com
Country
China
ProdList
26487
Advantage
56
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200-
Fax
028-81705658
Email
2851167785@qq.com
Country
China
ProdList
4690
Advantage
56
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9918
Advantage
58
Nanjing Leon Biological Technology Co., Ltd.
Tel
25-84523390-127
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5513
Advantage
55
Lynnchem
Tel
029-85992781-
Email
info@lynnchem.com
Country
China
ProdList
4461
Advantage
58
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805
Email
liugang@njpeptide.com
Country
China
ProdList
9924
Advantage
55
Novachemistry
Tel
44-20819178-90
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4384
Advantage
58
Aikon International Limited
Tel
025-58851090-
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15153
Advantage
58

4549-02-4, MACULOSINRelated Search:


  • MACULOSIN
  • CYCLO(-PRO-TYR)
  • A-19C
  • Antibiotic A-19C
  • Antibiotic ML-1532II
  • Cyclo(L-Tyr-L-Pro-)
  • ML-1532II
  • (3S,8aS)-3-(4-hydroxybenzyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-quinone
  • (3S,8aS)-3-[(4-hydroxyphenyl)methyl]-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • cyclo(L-Pro-L-Tyr)
  • (3S,8aS)-Hexahydro-3-[(4-hydroxyphenyl)methyl]pyrrolo[1,2-a]pyrazine-1,4-dione
  • Cyclo(L-prolinyl-L-tyrosine)
  • Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-[(4-hydroxyphenyl)methyl]-, (3S,8aS)-
  • MACULOSIN USP/EP/BP
  • 4549-02-4
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Gene Regulation and Expression
  • Reagents
  • Tools for Gene Regulation Research