MACULOSIN
- Product Name
- MACULOSIN
- CAS No.
- 4549-02-4
- Chemical Name
- MACULOSIN
- Synonyms
- A-19C;0/4/49;ML-1532II;MACULOSIN;Maculosin TFA;CYCLO(-PRO-TYR);Antibiotic A-19C;cyclo(L-Pro-L-Tyr);Cyclo(L-Tyr-L-Pro-);MACULOSIN USP/EP/BP
- CBNumber
- CB0265753
- Molecular Formula
- C14H16N2O3
- Formula Weight
- 260.29
- MOL File
- 4549-02-4.mol
MACULOSIN Property
- Melting point:
- 156-159 °C
- Boiling point:
- 581.4±43.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- A solid
- pka
- 9.92±0.15(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H311Toxic in contact with skin
H331Toxic if inhaled
H371May cause damage to organs
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P309+P311IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P311Call a POISON CENTER or doctor/physician.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P361Remove/Take off immediately all contaminated clothing.
P363Wash contaminated clothing before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 25019
- Product name
- Maculosin
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $130
- Updated
- 2024/03/01
- Product number
- 25019
- Product name
- Maculosin
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $416
- Updated
- 2024/03/01
- Product number
- C988385
- Product name
- Cyclo(L-prolinyl-L-tyrosine)
- Packaging
- 25mg
- Price
- $385
- Updated
- 2021/12/16
- Product number
- FC108323
- Product name
- Cyclo(-Pro-Tyr)
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- FC108323
- Product name
- Cyclo(-Pro-Tyr)
- Packaging
- 1g
- Price
- $273
- Updated
- 2021/12/16
MACULOSIN Chemical Properties,Usage,Production
Description
Maculosin is a diketopiperazine metabolite produced by A. alternata, L. capsici, Streptomyces, and the Gram-negative, nonobligate predator bacterial strain 679-2. It acts as a host-specific phytotoxin, inducing formation of weeping necrotic lesions in leaves of spotted knapweed (C. maculosa) when used at a concentration of 10 μM. Maculosin reduces the growth of the plant pathogenic bacteria X. axonopodis and R. solanacearum (MICs = 31.25 μg/ml) as well as the pathogenic oomycetes P. cactorum, P. capsici, P. cinnamomi, P. infestans, and P. ultimum when used at concentrations ranging from 10 to 100 mg/ml. Maculosin also inhibits the growth of M. luteus, M. smegmatis, S. cerevisiae, C. albicans, C. neoformans, and A. niger when used in combination with pyrrolnitrin or banegasin.
Uses
Cyclo(L-prolinyl-L-tyrosine) is a diketopiperazine derivative isolated from Bacillus thuringiensis and Bacillus endophyticus.
Uses
Cyclo(L-Pro-L-Tyr) (maculosin) is a diketopiperazine formed by the fusion of tyrosine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Pro-L-Tyr) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Pro-L-Tyr) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of cyclo(L-Pro-L-Tyr) is not known, its activity suggests the existence of cross talk among bacterial signalling systems. Cyclo(L-Pro-L-Tyr) was identified as a host-specific toxin produced by Alternaria alternata on spotted knapweed.
Definition
ChEBI: A homodetic cyclic peptide that is a dipeptide composed of L-proline and L-tyrosine joined by peptide linkages.
MACULOSIN Preparation Products And Raw materials
Raw materials
Preparation Products
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- 86-(0)29-85992781 17792393971
- info@lynnchem.com
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- China
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- 44-20819178-90 02081917890
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- (0)2080432064
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- United Kingdom
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- 82387566-801
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- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com
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View Lastest Price from MACULOSIN manufacturers
- Product
- MACULOSIN 4549-02-4
- Price
- US $0.00/gram
- Min. Order
- 1gram
- Purity
- 99%
- Supply Ability
- 10kg
- Release date
- 2022-02-17